Review
Biochemistry & Molecular Biology
Fatima Ijaz, Hafiz Muhammad Tahir, Shaukat Ali, Aamir Ali, Hooria Ashraf Khan, Ayesha Muzamil, Hafiz Hamid Manzoor, Kunza Abdul Qayyum
Summary: The need for biocompatible drug carriers has increased, and researchers are interested in developing diverse and complex biomaterial-based carriers. Hydrogels are beneficial drug carriers due to their tunable structure and ability to release drugs at target sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Polymer Science
Anupama Devi V. K, Rohin Shyam, Arunkumar Palaniappan, Amit Kumar Jaiswal, Tae-Hwan Oh, Arputharaj Joseph Nathanael
Summary: The review highlights the importance of smart self-healing hydrogels, their self-healing mechanisms, evaluation methods, and applications. It also discusses the use of composite materials to enhance mechanical properties, as well as methods for evaluating self-healing properties and recent advancements in 3D bioprinting. Finally, it presents current challenges and future perspectives in the field.
Review
Engineering, Environmental
Akbar Mirzaei, Maryam Esmkhani, Mahsa Zallaghi, Zahra Nezafat, Shahrzad Javanshir
Summary: Carrageenan, a renewable polymer derived from red algae, has valuable properties such as water absorption, gel formation, and antibacterial effects. It shows great potential in biomedical and environmental applications.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Liling Chen, Run Meng, Rui Qing, Wenfeng Li, Ziwei Wang, Yao Hou, Jia Deng, Wei Pu, Zibin Gao, Bochu Wang, Shilei Hao
Summary: We have successfully developed robust keratin hydrogels based on mechanism study through recombinant proteins, which outperform combinations of native proteins in mechanical properties and in biomedical applications.
Review
Polymer Science
Sher Ali Khan, Luqman Ali Shah, Mehwish Shah, Ishrat Jamil
Summary: Hydrogels are important in biomedical field due to their unique characteristics such as high water content, soft and flexible nature, biodegradability, and biocompatibility. Their resemblance to living body tissues allows for extensive application in various biomedical purposes. This review provides a detailed overview of polymer hydrogel-based inventions and products, as well as insights into potential future developments.
Article
Polymer Science
Ana P. C. Almeida, Joao N. Saraiva, Goncalo Cavaco, Raquel P. Portela, Catarina R. Leal, Rita G. Sobral, Pedro L. Almeida
Summary: Bacterial cellulose-based membranes have gained increasing attention as dressings for healing purposes. This study produced, modified, and characterized hydrated and dehydrated BC membranes for biomedical applications. The results showed that the cross-linked bacterial cellulose membranes exhibit suitable physical properties for use as wound dressings.
EUROPEAN POLYMER JOURNAL
(2022)
Review
Polymer Science
Mohammad Javed Ansari, Rahul R. Rajendran, Sourav Mohanto, Unnati Agarwal, Kingshuk Panda, Kishore Dhotre, Ravi Manne, A. Deepak, Ameeduzzafar Zafar, Mohd Yasir, Sheersha Pramanik
Summary: This review presents the wide range of applications and development status of smart hydrogels based on PNIPAM in the field of biomedical science, and summarizes the challenges and opportunities that lie ahead.
Review
Polymer Science
Yaxin Xie, Qiuyue Guan, Jiusi Guo, Yilin Chen, Yijia Yin, Xianglong Han
Summary: Hydrogels, as hydrophilic polymer networks, have shown significant potential in biomedical applications. Recent studies have focused on embedding exosomes into hydrogels to maintain their biological activity and achieve controlled release.
Review
Biochemistry & Molecular Biology
Samira Malekmohammadi, Negar Sedghi Aminabad, Amin Sabzi, Amir Zarebkohan, Mehdi Razavi, Massoud Vosough, Mahdi Bodaghi, Hajar Maleki
Summary: Smart/stimuli-responsive hydrogels have diverse applications in the biomedical field, with the ability to change behavior in response to external stimuli; technologies like 4D bioprinting have expanded the possibilities of using smart hydrogels in various biomedical applications, driving innovation and development in the field.
Review
Biochemistry & Molecular Biology
Wei Liu, Haishun Du, Ting Zheng, Chuanling Si
Summary: Bacterial cellulose (BC) and its derivatives are valuable natural ingredients for biomedical and medical applications. BC-based composite hydrogels have broad application prospects in the biomedical field, with good biocompatibility and excellent properties.
CURRENT MEDICINAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Pedro Lavrador, Marco R. Esteves, Vitor M. Gaspar, Joao F. Mano
Summary: Recent advances in the design of stimuli-responsive nanocomposite hydrogels have expanded their potential for operating as advanced systems in various biomedical applications, benefitting from tailored single or multi-responsiveness. The combination of hydrogels and nanoparticles showcases an intrinsic ability to react to external or internal/physiological stimuli, developing intelligent systems with application-oriented features.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Biomedical
Qinghe Wang, Yan Zhang, Yue Ma, Miao Wang, Guoqing Pan
Summary: Nano-crosslinked dynamic hydrogels, which combine the properties of dynamic hydrogels and nanomaterials, have been extensively studied in biomedical applications. By incorporating nanomaterials as crosslinkers, the mechanical properties of hydrogels can be improved and additional functionalities can be achieved. These hydrogels show excellent biocompatibility and can promote cell proliferation and differentiation.
MATERIALS TODAY BIO
(2023)
Review
Engineering, Biomedical
Mohammad Hadi Norahan, Sara Cristina Pedroza-Gonz, Monica Gabriela Sanchez-Salazar, Mario Moises Alvarez, Grissel Trujillo de Santiago
Summary: Chronic wounds have become a major problem in healthcare systems, leading to death worldwide. Engineering wound dressings with hydrogels can significantly improve healing time, reduce infections, and lower costs. Hydrogels provide a protective barrier, mimic the extracellular matrix, and create a moist environment. Different fabrication methods and properties of hydrogels have been extensively studied for wound healing applications, including the use of additives to enhance tissue regeneration. Hydrogel engineering offers smart solutions for effective wound healing, with capabilities such as inhibiting bacterial growth, promoting re-epithelialization, and improving tissue functionality.
BIOACTIVE MATERIALS
(2023)
Review
Chemistry, Physical
Lori M. Estes Bright, Yi Wu, Elizabeth J. Brisbois, Hitesh Handa
Summary: Hydrogels, with their hydrophilic properties and tissue-like mechanical properties, have a wide range of advantages in biomedical treatments. Nitric oxide's roles in the body have sparked research into biomimetic solutions, and hydrogels as nitric oxide delivery vehicles show promise in many applications.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2023)
Article
Polymer Science
Sophie Au-Yong, Melike Firlak, Emily R. Draper, Sofia Municoy, Mark D. Ashton, Geoffrey R. Akien, Nathan R. Halcovitch, Sara J. Baldock, Pierre Martin-Hirsch, Martin F. Desimone, John G. Hardy
Summary: Electroactive hydrogels based on derivatives of polyethyleneglycol (PEG), chitosan and polypyrrole were prepared using photopolymerization and oxidative chemical polymerization methods. The conductive gels showed lower swelling and higher mechanical strength compared to non-conductive gels. In vitro studies demonstrated the potential of these hydrogels for biomedical applications, including cell adhesion and proliferation assessment, and drug delivery studies.
Review
Chemistry, Analytical
Sonia M. Rodrigues M. Oliveira, Antonio Rebocho, Ehsan Ahmadpour, Veeranoot Nissapatorn, Maria de Lourdes Pereira
Summary: Type 1 diabetes mellitus is a common autoimmune disease in young patients, characterized by the destruction of pancreatic beta-cells and insulin deficiency. Current treatment options, such as islet transplantation and stem cell therapy, show promise but face various challenges.
Review
Immunology
Suthinee Sangkanu, Alok K. K. Paul, Julalak Chuprom, Watcharapong Mitsuwan, Rachasak Boonhok, Maria de Lourdes Pereira, Sonia Marlene Rodrigues Oliveira, Polrat Wilairatana, Mohammed Rahmatullah, Christophe Wiart, Muhammad Nawaz, Chea Sin, Sunil Kayesth, Veeranoot Nissapatorn
Summary: Giardia infection can cause diarrhea and is the third most common cause of diarrhea and death in children under five. Antimicrobial drugs are commonly used to treat giardiasis, but vaccination may be a potential means of control and protection against this parasitic disease outbreak.
Editorial Material
Chemistry, Medicinal
Srushti Tambe, Rohit Kumar, Purnima Amin, Monalisa Mishra, Madhu Gupta, Kavitha Govarthanan, Ashwin Kumar Narasimhan, Piyush Kumar Gupta
Summary: Organoids offer an opportunity to study the effects of diseases on cellular physiology, human tissues, and organs. They are crucial tools for analyzing biomaterial toxicity, discovering new drugs, and advancing regenerative medicine.
FUTURE MEDICINAL CHEMISTRY
(2023)
Article
Veterinary Sciences
Kareem Hatam-Nahavandi, David Carmena, Mostafa Rezaeian, Hamed Mirjalali, Hanieh Mohammad Rahimi, Milad Badri, Aida Vafae Eslahi, Farzaneh Faraji Shahrivar, Sonia Rodrigues M. Oliveira, Maria de Lourdes Pereira, Ehsan Ahmadpour
Summary: This study investigated the prevalence of intestinal parasites in livestock in Iranshahr County, Southeastern Iran. Most animals studied were infected with at least one species of intestinal parasite. It is important to conduct parasitological monitoring in livestock and take preventive measures to prevent the spread of parasites to humans.
VETERINARY SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
Watcharapong Mitsuwan, Phirabhat Saengsawang, Juthatip Jeenkeawpieam, Veeranoot Nissapatorn, Maria de Lourdes Pereira, Warangkana Kitpipit, Thotsapol Thomrongsuwannakij, Saranporn Poothong, Sasi Vimon
Summary: Microencapsulated probiotic with antibacterial activity against avian pathogenic Escherichia coli (APEC) was developed in this study. Pediococcus acidilactici was identified as the probiotic based on its tolerance toward in vitro gastrointestinal tract conditions, hydrophobicity, and auto-aggregation. The probiotic's culture supernatant exhibited strong antibacterial activity against clinical APEC isolates.
Article
Biochemistry & Molecular Biology
Jovita Kanoujia, Anjali Das, Neha Raina, Ginpreet Kaur, Sandeep K. Singh, Hardeep S. Tuli, Ashish Garg, Madhu Gupta
Summary: Breast cancer is the leading cause of cancer-related death in women worldwide, and drug resistance, especially mediated by breast cancer resistance protein (BCRP), is a major challenge faced by researchers. It is crucial to choose drugs based on the tumor's clinical and molecular attributes to improve treatment efficacy and minimize harm. The use of marine flora and marine-derived products in breast cancer treatment is vital in preventing drug resistance.
Editorial Material
Biotechnology & Applied Microbiology
Vaishali Sunil Mishra, Preeti Tiwari, Madhu Gupta, Piyush Kumar Gupta
Summary: Lipid-based nanodrug delivery systems have great potential in the therapeutic intervention for leishmaniasis by improving drug solubility and targeted delivery.
Review
Medicine, General & Internal
Filipa G. Mateus, Silvia Moreira, Ana D. Martins, Pedro F. Oliveira, Marco G. Alves, Maria de Lourdes Pereira
Summary: L-Carnitine, a natural antioxidant, supports male reproductive health by improving sperm quality and fertility.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Ruben Moreira, Ana D. Martins, Marco G. Alves, Maria de Lourdes Pereira, Pedro F. Oliveira
Summary: Low testosterone levels are a major cause of male infertility, and endocrine-disrupting chemicals such as chromium (Cr) can affect testicular steroidogenesis and male fertility. In particular, Cr(III) picolinate (CrPic(3)) has been found to inhibit enzymes involved in steroidogenesis and impact reactive oxygen species (ROS) levels, testosterone levels, and sperm motility and count. However, further research is needed to fully understand the effects of CrPic(3) on male fertility and ensure its safety for use by men.
Article
Agriculture, Dairy & Animal Science
Paparwee Sungkatavat, Haemarat Khongkhai, Wilasinee Kanchana, Phirabhat Saengsawarng, Suthinee Sangkanu, Veeranoot Nissapatorn, Maria de Lourdes Pereira, Julalak Chorachoo Ontong, Watcharapong Mitsuwan
Summary: The extract and teat dipping solution containing Piper betle extract showed potent antibacterial activity against mastitis-causing staphylococci and significantly inhibited biofilm formation.
Article
Education & Educational Research
Patricia Pinto-Pinho, Ana Ferreira, Barbara Matos, Joana Santiago, Magda Carvalho Henriques, Pedro Oliveira Corda, Tania Lima, Mario Rodrigues, Maria de Lourdes Pereira, Margarida Fardilha
Summary: The World Cafe method can enhance student engagement, foster knowledge-sharing, and improve collaborative work skills in biomedical education. Students prefer this method over traditional lectures, and the availability of modern facilities can increase their motivation to learn.
INNOVATIONS IN EDUCATION AND TEACHING INTERNATIONAL
(2023)
