The Circadian Gene Clock Regulates Bone Formation Via PDIA3

Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype

(2016) William E. Samsa et al.   BONE

Clock GeneBmal1Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1

(2016) Wei Yang et al.   ENDOCRINOLOGY

Circadian Clock Regulates Bone Resorption in Mice

(2016) Cheng Xu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation

(2015) Jonathan O. Lipton et al.   CELL

ER Stress During the Pubertal Growth Spurt Results in Impaired Long-Bone Growth in Chondrocyte-Specific ERp57 Knockout Mice

(2015) Andrea Linz et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

(2015) Michal Dudek et al.   JOURNAL OF CLINICAL INVESTIGATION

An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation

(2015) Chao Lu et al.   Cell Reports

Signaling components of the 1α,25(OH)2D3-dependent Pdia3 receptor complex are required for Wnt5a calcium-dependent signaling

(2014) Maryam Doroudi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glucocorticoids mediate circadian timing in peripheral osteoclasts resulting in the circadian expression rhythm of osteoclast-related genes

(2014) Yuko Fujihara et al.   BONE

The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock

(2014) Jana Husse et al.   FASEB JOURNAL

Impaired Bone Formation in Pdia3 Deficient Mice

(2014) Yun Wang et al.   PLoS One

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1α,25(OH)2D3

(2013) Jiaxuan Chen et al.   CELLULAR SIGNALLING

A Transcriptome-proteome Integrated Network Identifies Endoplasmic Reticulum thiol oxidoreductase (ERp57) as a Hub that Mediates Bone Metastasis

(2013) Naiara Santana-Codina et al.   MOLECULAR & CELLULAR PROTEOMICS

New insights on membrane mediated effects of 1α,25-dihydroxy vitamin D3 signaling in the musculoskeletal system

(2013) Maryam Doroudi et al.   STEROIDS

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

(2013) Kazuhiro Shimomura et al.   eLife

Comparison of β-Adrenergic and Glucocorticoid Signaling on Clock Gene and Osteoblast-Related Gene Expressions in Human Osteoblast

(2012) Shintaro Komoto et al.   CHRONOBIOLOGY INTERNATIONAL

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Phospholipase A2 activating protein is required for 1α,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3

(2012) Maryam Doroudi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The contribution of bone to whole-organism physiology

(2012) Gérard Karsenty et al.   NATURE

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Disruption of the circadian clock due to theClockmutation has discrete effects on aging and carcinogenesis

(2011) Marina P. Antoch et al.   CELL CYCLE

The circadian molecular clock creates epidermal stem cell heterogeneity

(2011) Peggy Janich et al.   NATURE

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

ERp57 Modulates STAT3 Signaling from the Lumen of the Endoplasmic Reticulum

(2009) Helen Coe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS