Article
Clinical Neurology
Ana Laura Hernandez-Ledesma, Adriana Jheny Rodriguez-Mendez, Lilia Susana Gallardo-Vidal, Ma. Ludivina Robles-Osorio, Maria Elena Villagran-Herrera, Ma. Guadalupe Martinez-Pena, Teresa Garcia-Gasca
Summary: This study evaluated serum vitamin D and cytokine concentrations, as well as bone density, in Mexican individuals with multiple sclerosis (MS). The majority of participants exhibited some degree of vitamin D inadequacy, and pro-inflammatory markers were detectable in the participants. However, non-significant correlations were found between vitamin D concentration, bone mineral density, and pro-inflammatory markers. Further research is needed to explore the physiological causes and effects of vitamin D deficiency in individuals with MS.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2021)
Article
Endocrinology & Metabolism
Katherine W. Reeves, Gabriela Vieyra, Nydjie P. Grimes, Jaymie Meliker, Rebecca D. Jackson, Jean Wactawski-Wende, Robert Wallace, R. Thomas Zoeller, Carol Bigelow, Susan E. Hankinson, JoAnn E. Manson, Jane A. Cauley, Antonia M. Calafat
Summary: The study found that certain phthalate biomarkers were associated with greater percentage decreases in total hip and femoral neck bone mineral density (BMD), suggesting that phthalate exposure may have clinically significant effects on BMD and potentially increase fracture risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Environmental Sciences
Huan He, Min Li, Bailing Liu, Zhan Zhang
Summary: Previous studies have found a positive association between methylparaben (Mep) and bone mineral density (BMD) in adults, but limited research has been conducted in children and adolescents. This study examined 1830 individuals aged 8-19 years and found a positive association between Mep and BMD. The association was particularly significant in females and children aged 12-19 years.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Endocrinology & Metabolism
Yu-Mei Hsueh, Ya-Li Huang, Hsi-Hsien Chen, Horng-Sheng Shiue, Ying-Chin Lin, Ru-Lan Hsieh
Summary: The study found a significant negative correlation between increasing blood lead levels and decreasing bone density, as well as a similar trend with increasing total urinary arsenic levels. High blood lead or arsenic exposure, as well as alcohol intake, were associated with an increased odds ratio for bone loss.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Immunology
Anjali Sharma, Donald R. Hoover, Qiuhu Shi, Phyllis C. Tien, Kathleen M. Weber, Jayesh G. Shah, Michael T. Yin
Summary: Among pre-, peri-, and postmenopausal women, low bone mineral density (BMD) was more common in women with HIV compared to those without HIV. HIV infection and menopausal stage were independent predictors of lower BMD and had additive effects on lumbar spine and total hip BMD.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Fernanda Guedes Rodrigues, Milene Subtil Ormanji, Igor Gouveia Pietrobom, Ana Cristina Carvalho de Matos, Martin H. H. De Borst, Ita Pfeferman Heilberg
Summary: The study investigated the association of urinary calcium with serum sclerostin, bone mineral density, and body composition in stone formers. The results showed that serum sclerostin is associated with urinary calcium levels, suggesting a potential additional role of sclerostin in calcium reabsorption in the kidneys.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Namki Hong, Jung Ho Kim, Graham Treece, Hyeon Chang Kim, Jun Yong Choi, Yumie Rhee
Summary: Middle-aged men living with human immunodeficiency virus (MLWH) have a significantly higher risk of hip fracture, almost a decade earlier than those without infection. Limited data on cortical and trabecular bone deficit in MLWH were observed. This study found that MLWH had lower hip bone density and deficits in certain bone parameters compared to age and body mass index-matched controls.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Nutrition & Dietetics
Christa Ellis, Herculina S. Kruger, Michelle Viljoen, Joel A. Dave, Marlena C. Kruger
Summary: The study found that changes in bone mineral density and bone resorption markers over two years were minimal in black postmenopausal women living with HIV. Despite a decrease in serum vitamin D, there were small or no changes in BMD and CTx over the 2-year period.
Article
Endocrinology & Metabolism
Wei Zhang, Wei Zhao, Wei Li, Qi Geng, Rui Zhao, Yungui Yang, Luyan Lv, Weiwen Chen
Summary: Osteoporosis is a debilitating disease that is often overlooked and poorly studied in elderly male patients. This study aims to investigate molecular alterations in immune cells in men with osteoporosis and identify potential immunomodulatory strategies for treatment. The results show that there are molecular changes in immune cells of male osteoporotic patients and suggest potential therapeutic value of immunomodulation.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Immunology
Johannes M. Schwenke, Christian W. Thorball, Isabella C. Schoepf, Lene Ryom, Barbara Hasse, Olivier Lamy, Alexandra Calmy, Gilles Wandeler, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Roger D. Kouyos, Huldrych F. Gunthard, Bruno Ledergerber, Jacques Fellay, Felix Burkhalter, Philip E. Tarr, Swiss HIV Cohort Study
Summary: Individual polygenic risk score is associated with osteoporosis in people living with HIV, even after adjusting for traditional and HIV-related risk factors. This study highlights the importance of a polygenic risk score in predicting low bone mineral density in HIV patients.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Semran Thamer, Mirjana Stevanovic, Jay C. Buckey
Summary: Microgravity-induced bone loss leads to increased urinary calcium excretion, increasing the risk of kidney stone formation. Not all individuals experience the same degree of increase, and certain pre-flight characteristics may help identify individuals who would benefit from in-flight monitoring.
Article
Medicine, General & Internal
Juan Luo, Mingjiang Liu, Zhong Zheng, Ya Zhang, Ruijie Xie
Summary: This study investigated the association between urine caffeine and its metabolites and bone mineral density (BMD) in people aged 8 to 19. The results showed that there were positive associations between urinary paraxanthine, theobromine, and caffeine with total BMD, while the association between urinary theophylline and total BMD was negative. Interestingly, a U-shaped association between urinary paraxanthine and urinary caffeine was found in women. The correlation between urinary caffeine and its metabolites and total BMD differed by sex and race.
Article
Environmental Sciences
Peng Tang, Qian Liao, Huishen Huang, Qian Chen, Jun Liang, Ying Tang, Yong Zhou, Xiaoyun Zeng, Xiaoqiang Qiu
Summary: Previous studies have shown that exposure to metals can affect bone health, but these studies mostly focused on a few common hazardous metals. This study found that exposure to barium (Ba) is negatively correlated with bone mineral density (BMD), and there may be joint effects between lead and barium, as well as between cadmium and barium, on BMD.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Medicine, General & Internal
Pilar Vizcarra, Juan Gallego, Cristina Sobrino, Walter A. Sifuentes, Maria J. Vivancos, Jose L. Casado
Summary: A study on bone mass in individuals with HIV in Spain showed that this population had lower bone mineral density compared to the general population in almost all age groups. This finding needs to be considered when making recommendations.
Article
Nutrition & Dietetics
Alexandra K. Calor, Dana F. J. Yumani, Mirjam M. van Weissenbruch
Summary: The research indicates that fat intake in the first postnatal weeks is positively associated with BMC and BMD at term corrected age, while protein and fat intake in the early weeks of life can predict BMD at six months corrected age. These findings suggest that early nutritional intervention is crucial for bone health in the first months of life.
Article
Nutrition & Dietetics
Ligia Moriguchi Watanabe, Ana C. Bueno, Livia F. de Lima, Rafael Ferraz-Bannitz, Renata Dessordi, Mariana P. Guimaraes, Maria C. Foss-Freitas, Fernando Barbosa, Anderson M. Navarro
Summary: The study found that SNPs in selenoproteins were associated with individual responses to Brazil nut consumption, indicating that variations in Se homeostasis may impact health outcomes.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Rheumatology
Sergio Setsuo Maeda, Barbara Santarosa Emo Peters, Ligia Araujo Martini, Hannah Karen Moreira Antunes, Maria Cristina Gonzalez, Henrique Pierotti Arantes, Carla M. Prado, Camila Lemos Pinto, Iana Mizumukai de Araujo, Francisco Jose Albuquerque de Paula, Joao Lindolfo Cunha Borges, Ben-Hur Albergaria, Marcela Ushida, Guilherme Cardenaz de Souza, Laura Maria Carvalho de Mendonca, Mirley do Prado, Marcelo de Medeiros Pinheiro
Summary: This study discusses the technical aspects of body composition assessment by dual-energy X-ray absorptiometry (DXA) and other methods based on the most recent scientific evidence. DXA is considered the gold-standard method for body composition assessment, particularly for evaluating fat mass, due to its accuracy, precision, cost-effectiveness, and ability to evaluate all three compartments. Attention to quality control procedures, preparation, removal of external artifacts, imaging acquisition, and data analysis is crucial for reliable and reproducible DXA reports.
ADVANCES IN RHEUMATOLOGY
(2022)
Article
Environmental Sciences
Igor Massari Correia, Anderson Marliere Navarro, Jessica Fernanda Correa Cordeiro, Euripedes Barsanulfo Goncalves Gomide, Lisa Fernanda Mazzonetto, Alcivandro de Sousa Oliveira, Emerson Sebastiao, Bruno Augusto Aguilar, Denise de Andrade, Dalmo Roberto Lopes Machado, Andre Pereira dos Santos
Summary: This study developed sex-specific anthropometric models to predict bone mineral content (BMC) in people living with HIV (PWH). The models showed high coefficients of determination and reduced estimation errors, providing a valid and low-cost alternative for monitoring bone health in PWH.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Barbara C. Silva, Miguel Madeira, Catarina Brasil D'Alva, Sergio Setsuo Maeda, Narriane Chaves Pereira de Holanda, Monique Nakayama Ohe, Vera Szejnfeld, Cristiano A. F. Zerbini, Francisco Jose Albuquerque de Paula, Francisco Bandeira
Summary: Previously, antiresorptive drugs were considered the first-line therapy for osteoporosis, with anabolic agents as a last resort. However, recent studies have shown that anabolic agents are more effective in reducing fractures than antiresorptive medications. It has also been found that treating patients with anabolic agents followed by antiresorptive therapy maximizes the increase in bone mineral density. International guidelines now propose an individualized approach to osteoporosis treatment based on fracture risk, with a category of patients at very high risk managed with anabolic agents as first-line therapy.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Beatriz M. Oliveira, Lucas Ferreira de Almeida, Amanda L. Deluque, Claudia S. Souza, Ana Livia D. Maciel, Heloisa D. C. Francescato, Roberto S. Costa, Cleonice Giovanini, Francisco Jose A. de Paula, Terezila M. Coimbra
Summary: Cisplatin treatment is commonly used for cancer patients, but it often leads to acute kidney injury. This study found that bioactive vitamin D can attenuate the renal injury caused by cisplatin by reducing inflammation and vascular damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Luana Leticia Capato, Luciana Mendes Cangussu-Oliveira, Jaqueline Mello Porto, Beatriz Jeronimo, Juliana dos Santos Guilherme Ribeiro, Eduardo Ferrioli, Francisco Jose Albuquerque de Paula, Daniela Cristina Carvalho de Abreu
Summary: The study found that there is an association between hip abductors muscle strength and bone mineral density of the femoral neck (BMD-FN) as well as several clinical tests. This indicates that hip abductor muscle strength not only benefits balance and gait improvement, but also plays an important role in maintaining/improving bone mass in the femoral neck in older women.
JOURNAL OF CLINICAL DENSITOMETRY
(2023)
Article
Immunology
Erika G. Marques de Menezes, Jocelyn S. Liu, Scott A. Bowler, Leila B. Giron, Michelle L. D'Antoni, Cecilia M. Shikuma, Mohamed Abdel-Mohsen, Lishomwa C. Ndhlovu, Philip J. Norris
Summary: The study found that EVs expressing markers of monocyte activation and neuronal injury were elevated in HIV-infected individuals with cognitive impairment, suggesting that specific EV subsets may serve as novel biomarkers of neuronal injury in HIV infection. Additionally, levels of circulating platelet EVs were linked to monocyte activation, indicating a potential novel interaction in the pathogenesis of HIV-related cognitive impairment.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ana Carolina Momentti, Mariana de Souza Macedo, Ana Flavia de Sousa Silva, Vanessa Cristina de Oliveira Souza, Fernando Barbosa Junior, Sylvia do Carmo Castro Franceschini, Anderson Marliere Navarro
Summary: Pregnant women in a city of Southeastern Brazil have adequate iodine nutrition. Household salt storage and seasoning consumption are risk factors for insufficient iodine status.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Correction
Biochemistry & Molecular Biology
Ana Carolina Momentti, Mariana de Souza Macedo, Ana Flavia de Sousa Silva, Vanessa Cristina de Oliveira Souza, Fernando Barbosa Jr, Sylvia do Carmo Castro Franceschini, Anderson Marliere Navarro
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Neurosciences
Carrie D. D. Johnston, Erika G. Marques de Menezes, Scott Bowler, Eugenia L. L. Siegler, Courtney Friday, Philip J. J. Norris, Michelle C. C. Rice, Mary E. E. Choi, Marshall J. J. Glesby, Lishomwa C. C. Ndhlovu
Summary: This study explored the association between extracellular vesicles, cell-free mitochondrial DNA, and cognitive dysfunction in older people with HIV. The findings suggest that plasma EVs, urine cf-mtDNA, and 4-meter walk time can predict neurocognitive impairment.
JOURNAL OF NEUROVIROLOGY
(2023)
Article
Nutrition & Dietetics
Soraya Regina Abu Jamra, Camila Gomes Komatsu, Fernando Barbosa Jr, Persio Roxo-Junior, Anderson Marliere Navarro
Summary: The increase in life expectancy can be attributed to the world's socioeconomic, sanitary, and nutritional conditions. A higher diversity score in diet has been shown to reduce the risk of malnutrition and improve health status. Zinc and selenium deficiencies can lead to immune system abnormalities and increased susceptibility to infections.
Article
Rehabilitation
Melise Jacon Peres-Ueno, Luana Leticia Capato, Jaqueline Mello Porto, Isabela Ferreira AdaO, Jamilly Maciel Gomes, Carlos Fernando Pereira da Silva Herrero, Marcello Henrique Nogueira-Barbosa, Francisco Jose Albuquerque de Paula, Eduardo Ferrioli, Daniela Cristina Carvalho de Abreu
Summary: This study investigated the association between vertebral fragility fractures and lower limb muscle strength and physical performance in women with low bone mass. The presence of vertebral fracture was found to be independently associated with decreased lower limb muscle strength and poor physical performance. Therefore, strength and power training programs for the lower limbs could improve physical performance.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Mariana Lima Mascarenhas Moreira, Iana Mizumukai de Araujo, Sandra Yasuyo Fukada, Lucas Gabriel R. Venturini, Natalia Rossin Guidorizzi, Carlos Ernesto Garrido, Clifford J. Rosen, Francisco Jose Albuquerque de Paula
Summary: This cross-sectional observational study aimed to assess adipose tissue in DS patients and define their bone phenotype. DS patients showed increased adiposity in the lumbar spine and muscle tissue, as well as impaired bone quality and lower bone mass in the 1/3 radius. The study also found associations between insulin resistance, lipids, bone turnover markers, and bone parameters in DS patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biology
J. G. Maciel, C. E. G. Salmon, B. S. Hosseini, P. M. Azevedo-Marques, F. J. A. de Paula, M. H. Nogueira-Barbosa
Summary: This study evaluated the bone texture attributes (TA) extracted from routine lumbar spine MRI and their correlation with vertebral fragility fractures (VFF) and bone mineral density (BMD). The results showed that two TA (cluster tendency and variance) were significantly lower in the fracture group. A significant correlation was also found between BMD and several texture attributes.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2022)
Review
Endocrinology & Metabolism
Iona Mizumukai de Araujo, Mariana Lima Mascarenhas Moreira, Francisco Jose Albuquerque de Paula
Summary: Diabetes mellitus and osteoporosis are common diseases that have mutual risk factors and influences. This review discusses the factors associated with increased risk of fractures in individuals with diabetes and explores the shared factors affecting the treatment of both diseases.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2022)
