To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity

Microplastics and human health

(2021) A. Dick Vethaak et al.   SCIENCE

Critical review on microplastics in fecal matter: research progress, analytical methods and future outlook

(2021) Fermín Pérez-Guevara et al.   SCIENCE OF THE TOTAL ENVIRONMENT

You are what you eat: Microplastics in the feces of young men living in Beijing

(2021) Na Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Endocrine disruption in Crohn’s disease: Bisphenol A enhances systemic inflammatory response in patients with gut barrier translocation of dysbiotic microbiota products

(2021) Raquel Linares et al.   FASEB JOURNAL

Plastics contamination of store-bought rice

(2021) Claudia Dessì et al.   JOURNAL OF HAZARDOUS MATERIALS

Long-term chronic exposure to di-(2-ethylhexyl)-phthalate induces obesity via disruption of host lipid metabolism and gut microbiota in mice

(2021) Henghai Su et al.   CHEMOSPHERE

Disruption of Intestinal Homeostasis Through Altered Responses of the Microbial Community, Energy Metabolites, and Immune System in Zebrafish After Chronic Exposure to DEHP

(2021) Pan-Pan Jia et al.   Frontiers in Microbiology

Activatable Molecular Probes for Second Near-Infrared Fluorescence, Chemiluminescence, and Photoacoustic Imaging

(2020) Kanyi Pu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ranking environmental degradation trends of plastic marine debris based on physical properties and molecular structure

(2020) Kyungjun Min et al.   Nature Communications

A Detailed Review Study on Potential Effects of Microplastics and Additives of Concern on Human Health

(2020) Campanale et al.   International Journal of Environmental Research and Public Health

Degradation Rates of Plastics in the Environment

(2020) Ali Chamas et al.   ACS Sustainable Chemistry & Engineering

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis in CD-1 mice

(2020) Dan Feng et al.   ENVIRONMENTAL POLLUTION

Environmental exposure to nonylphenol and cancer progression Risk–A systematic review

(2020) Zahra Noorimotlagh et al.   ENVIRONMENTAL RESEARCH

Evaluation of Microbiome-Host Relationships in the Zebrafish Gastrointestinal System Reveals Adaptive Immunity Is a Target of Bis(2-ethylhexyl) Phthalate (DEHP) Exposure

(2020) Ondrej Adamovsky et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microstructure Characterization of Oceanic Polyethylene Debris

(2020) Laura Rowenczyk et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Assessment of cancer risk of microplastics enriched with polycyclic aromatic hydrocarbons

(2020) Madhu D. Sharma et al.   JOURNAL OF HAZARDOUS MATERIALS

Microbial degradation and other environmental aspects of microplastics/plastics

(2020) Jianhua Yuan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Endocrine Disruptors in Food: Impact on Gut Microbiota and Metabolic Diseases

(2020) Yolanda Gálvez-Ontiveros et al.   Nutrients

Ionic Liquids as Extractants for Nanoplastics

(2020) Roman Elfgen et al.   ChemSusChem

Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents

(2020) Gang Wang et al.   ENVIRONMENTAL POLLUTION

Micro- and nano-plastics in edible fruit and vegetables. The first diet risks assessment for the general population

(2020) Gea Oliveri Conti et al.   ENVIRONMENTAL RESEARCH

Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients

(2020) Quentin Leyrolle et al.   CLINICAL NUTRITION

Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

(2020) Yongfeng Deng et al.   ENVIRONMENT INTERNATIONAL

Estimation of the mass of microplastics ingested – A pivotal first step towards human health risk assessment

(2020) Kala Senathirajah et al.   JOURNAL OF HAZARDOUS MATERIALS

Plasticenta: First evidence of microplastics in human placenta

(2020) Antonio Ragusa et al.   ENVIRONMENT INTERNATIONAL

Systems toxicogenomics of prenatal low-dose BPA exposure on liver metabolic pathways, gut microbiota, and metabolic health in mice

(2020) Graciel Diamante et al.   ENVIRONMENT INTERNATIONAL

Reviewing nanoplastic toxicology: It's an interface problem

(2020) Shinji Kihara et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Multisystemic alterations in humans induced by bisphenol A and phthalates: Experimental, epidemiological and clinical studies reveal the need to change health policies

(2020) A. Martínez-Ibarra et al.   ENVIRONMENTAL POLLUTION

Sex-dependent effects of bisphenol A on type 1 diabetes development in non-obese diabetic (NOD) mice

(2019) Joella Xu et al.   ARCHIVES OF TOXICOLOGY

Methods for the analysis of submicrometer- and nanoplastic particles in the environment

(2019) Christian Schwaferts et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Are the primary characteristics of polystyrene nanoplastics responsible for toxicity and ad/absorption in the marine diatom Phaeodactylum tricornutum?

(2019) Marta Sendra et al.   ENVIRONMENTAL POLLUTION

Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo

(2019) Valerie Stock et al.   ARCHIVES OF TOXICOLOGY

Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells

(2019) Bing Wu et al.   CHEMOSPHERE

Robust Automatic Identification of Microplastics in Environmental Samples Using FTIR Microscopy

(2019) Gerrit Renner et al.   ANALYTICAL CHEMISTRY

Human Consumption of Microplastics

(2019) Kieran D. Cox et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis

(2019) Gloria Fackelmann et al.   MARINE POLLUTION BULLETIN

Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro

(2019) Michelle Hesler et al.   TOXICOLOGY IN VITRO

Assessment on interactive prospectives of nanoplastics with plasma proteins and the toxicological impacts of virgin, coronated and environmentally released-nanoplastics

(2019) Ponnusamy Manogaran Gopinath et al.   Scientific Reports

Detection of Various Microplastics in Human Stool

(2019) Philipp Schwabl et al.   ANNALS OF INTERNAL MEDICINE

Can Nanoplastics Alter Cell Membranes?

(2019) Oldamur Hollóczki et al.   CHEMPHYSCHEM

Nonylphenol causes shifts in microbial communities and nitrogen mineralization in soil microcosms

(2019) Stefania Mattana et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Bisphenol A increases intestinal permeability through disrupting intestinal barrier function in mice

(2019) Ling Feng et al.   ENVIRONMENTAL POLLUTION

Phthalate exposure alters gut microbiota composition and IgM vaccine response in human newborns

(2019) Yung-Ning Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Identifying a quick and efficient method of removing organic matter without damaging microplastic samples

(2019) Joana C. Prata et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Nanoplastics can change the secondary structure of proteins

(2019) Oldamur Hollóczki et al.   Scientific Reports

Transcriptional response provides insights into the effect of chronic polystyrene nanoplastic exposure on Daphnia pulex

(2019) Wenyi Zhang et al.   CHEMOSPHERE

Effects of polystyrene microbeads on cytotoxicity and transcriptomic profiles in human Caco‐2 cells

(2019) Shijin Wu et al.   ENVIRONMENTAL TOXICOLOGY

Environmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice

(2019) Ming Lei et al.   mSystems

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

(2019) Boqing Li et al.   CHEMOSPHERE

Laser Ablation as a Versatile Tool To Mimic Polyethylene Terephthalate Nanoplastic Pollutants: Characterization and Toxicology Assessment

(2018) Davide Magrì et al.   ACS Nano

Microplastics in the environment: Challenges in analytical chemistry - A review

(2018) Ana B. Silva et al.   ANALYTICA CHIMICA ACTA

Detection of nanoplastics in food by asymmetric flow field-flow fractionation coupled to multi-angle light scattering: possibilities, challenges and analytical limitations

(2018) Manuel Correia et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Low levels of microplastics (MP) in wild mussels indicate that MP ingestion by humans is minimal compared to exposure via household fibres fallout during a meal

(2018) Ana I. Catarino et al.   ENVIRONMENTAL POLLUTION

Dysbiosis of gut microbiota by chronic coexposure to titanium dioxide nanoparticles and bisphenol A: Implications for host health in zebrafish

(2018) Lianguo Chen et al.   ENVIRONMENTAL POLLUTION

Influence of gastrointestinal tract on metabolism of bisphenol A as determined by in vitro simulated system

(2018) Yonghua Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Marine microplastic debris: An emerging issue for food security, food safety and human health

(2018) Luís Gabriel Antão Barboza et al.   MARINE POLLUTION BULLETIN

Anthropogenic contamination of tap water, beer, and sea salt

(2018) Mary Kosuth et al.   PLoS One

Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice

(2018) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Analysis of microplastics in water by micro-Raman spectroscopy: Release of plastic particles from different packaging into mineral water

(2018) Darena Schymanski et al.   WATER RESEARCH

Identification of microplastics using Raman spectroscopy: Latest developments and future prospects

(2018) Catarina F. Araujo et al.   WATER RESEARCH

Synthetic Polymer Contamination in Bottled Water

(2018) Sherri A. Mason et al.   Frontiers in Chemistry

Cloud-Point Extraction Combined with Thermal Degradation for Nanoplastic Analysis Using Pyrolysis Gas Chromatography–Mass Spectrometry

(2018) Xiao-xia Zhou et al.   ANALYTICAL CHEMISTRY

Uptake, Whole-Body Distribution, and Depuration of Nanoplastics by the Scallop Pecten maximus at Environmentally Realistic Concentrations

(2018) Maya Al-Sid-Cheikh et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Overview of known plastic packaging-associated chemicals and their hazards

(2018) Ksenia J. Groh et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Distribution, sources and consequences of nutrients, persistent organic pollutants, metals and microplastics in South American estuaries

(2018) Mário Barletta et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Abundance and characteristics of microplastics in market bivalves from South Korea

(2018) Youna Cho et al.   ENVIRONMENTAL POLLUTION

Trace metals in polyethylene debris from the North Atlantic subtropical gyre

(2018) Jonathan Prunier et al.   ENVIRONMENTAL POLLUTION

Effects of polystyrene microplastics on the composition of the microbiome and metabolism in larval zebrafish

(2018) Zhiqin Wan et al.   CHEMOSPHERE

Plastic and Human Health: A Micro Issue?

(2017) Stephanie L. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Development of a method for the detection of polystyrene microplastics in paraffin-embedded histological sections

(2017) Cátia Gonçalves et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The effect of the protein corona on the interaction between nanoparticles and lipid bilayers

(2017) Desirè Di Silvio et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Xenoestrogen regulation of ERα/ERβ balance in hormone-associated cancers

(2017) Filippo Acconcia et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Effect of nonylphenol on the regulation of cell growth in colorectal cancer cells

(2017) Xuefeng Yang et al.   Molecular Medicine Reports

Quantitative investigation of the mechanisms of microplastics and nanoplastics toward zebrafish larvae locomotor activity

(2017) Qiqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The Plasticizer Bisphenol A Perturbs the Hepatic Epigenome: A Systems Level Analysis of the miRNome

(2017) Ludivine Renaud et al.   Genes

Discovery and technology for human health

(2017)   Nature Biomedical Engineering

The presence of microplastics in commercial salts from different countries

(2017) Ali Karami et al.   Scientific Reports

Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure

(2017) Yongfeng Deng et al.   Scientific Reports

Interaction of hydrophobic polymers with model lipid bilayers

(2017) D. Bochicchio et al.   Scientific Reports

Characterisation of nanoplastics during the degradation of polystyrene

(2016) Scott Lambert et al.   CHEMOSPHERE

Microplastics in mussels along the coastal waters of China

(2016) Jiana Li et al.   ENVIRONMENTAL POLLUTION

Bisphenol A alters gut microbiome: Comparative metagenomics analysis

(2016) Keng-Po Lai et al.   ENVIRONMENTAL POLLUTION

Plastic Debris Is a Human Health Issue

(2016) A. Dick Vethaak et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Understanding the Fragmentation Pattern of Marine Plastic Debris

(2016) Alexandra ter Halle et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastic as a Vector for Chemicals in the Aquatic Environment: Critical Review and Model-Supported Reinterpretation of Empirical Studies

(2016) Albert A. Koelmans et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Release of synthetic microplastic plastic fibres from domestic washing machines: Effects of fabric type and washing conditions

(2016) Imogen E. Napper et al.   MARINE POLLUTION BULLETIN

A review of the carcinogenic potential of bisphenol A

(2016) Darcie D. Seachrist et al.   REPRODUCTIVE TOXICOLOGY

Microplastic Pollution in Table Salts from China

(2015) Dongqi Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology

(2015) Hans Bouwmeester et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics in sediments: A review of techniques, occurrence and effects

(2015) Lisbeth Van Cauwenberghe et al.   MARINE ENVIRONMENTAL RESEARCH

The redox biology network in cancer pathophysiology and therapeutics

(2015) Gina Manda et al.   Redox Biology

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

(2015) Laura Poillet-Perez et al.   Redox Biology

Estrogen Receptors and Their Implications in Colorectal Carcinogenesis

(2015) Francesco Caiazza et al.   Frontiers in Oncology

Rapid bacterial colonization of low-density polyethylene microplastics in coastal sediment microcosms

(2014) Jesse P Harrison et al.   BMC MICROBIOLOGY

Human absorption, distribution, metabolism and excretion properties of drug molecules: a plethora of approaches

(2014) Claire Beaumont et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Dose-Dependent Incidence of Hepatic Tumors in Adult Mice following Perinatal Exposure to Bisphenol A

(2014) Caren Weinhouse et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Microplastics in bivalves cultured for human consumption

(2014) Lisbeth Van Cauwenberghe et al.   ENVIRONMENTAL POLLUTION

Microplastic is an Abundant and Distinct Microbial Habitat in an Urban River

(2014) Amanda McCormick et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

SCGB2A1 is a novel prognostic marker for colorectal cancer associated with chemoresistance and radioresistance

(2014) KOJI MUNAKATA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Secondary Structure of Corona Proteins Determines the Cell Surface Receptors Used by Nanoparticles

(2014) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Quality assessment of the blue mussel (Mytilus edulis): Comparison between commercial and wild types

(2014) B. De Witte et al.   MARINE POLLUTION BULLETIN

Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity

(2014) Agata P. Walczak et al.   Nanotoxicology

Towards Whole-Body Fluorescence Imaging in Humans

(2014) Sophie K. Piper et al.   PLoS One

Long-Term Sorption of Metals Is Similar among Plastic Types: Implications for Plastic Debris in Aquatic Environments

(2014) Chelsea M. Rochman et al.   PLoS One

Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice

(2014) Marta García-Arevalo et al.   PLoS One

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

Life in the “Plastisphere”: Microbial Communities on Plastic Marine Debris

(2013) Erik R. Zettler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Polystyrene Nanoparticles Perturb Lipid Membranes

(2013) Giulia Rossi et al.   Journal of Physical Chemistry Letters

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Effects of Particle Size and Surface Modification on Cellular Uptake and Biodistribution of Polymeric Nanoparticles for Drug Delivery

(2013) Sneha A. Kulkarni et al.   PHARMACEUTICAL RESEARCH

Permeation of polystyrene nanoparticles across model lipid bilayer membranes

(2013) Thomas H. F. Thake et al.   Soft Matter

Identification of polymer types and additives in marine microplastic particles using pyrolysis-GC/MS and scanning electron microscopy

(2013) Elke Fries et al.   Environmental Science-Processes & Impacts

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells

(2012) Anna Lesniak et al.   ACS Nano

Expression of oestrogen receptor β and prognosis of colorectal cancer

(2012) A Rudolph et al.   BRITISH JOURNAL OF CANCER

Induction of oxidative stress and histological changes in liver by subacute doses of butyl cyclohexyl phthalate

(2012) N. Ülkü Karabay Yavaşoğlu et al.   ENVIRONMENTAL TOXICOLOGY

Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa—A first in vivo study in human patients

(2012) Carsten Schmidt et al.   JOURNAL OF CONTROLLED RELEASE

Are baleen whales exposed to the threat of microplastics? A case study of the Mediterranean fin whale (Balaenoptera physalus)

(2012) Maria Cristina Fossi et al.   MARINE POLLUTION BULLETIN

Interactions of Engineered Nanoparticles with Organs Protected by Internal Biological Barriers

(2012) Antonio Pietroiusti et al.   Small

Adaptive micro and nanoparticles: Temporal control over carrier properties to facilitate drug delivery

(2011) Jin-Wook Yoo et al.   ADVANCED DRUG DELIVERY REVIEWS

The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells

(2011) Hongyun Tang et al.   BMC BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Adsorption of trace metals to plastic resin pellets in the marine environment

(2011) Luke A. Holmes et al.   ENVIRONMENTAL POLLUTION

Microplastics as contaminants in the marine environment: A review

(2011) Matthew Cole et al.   MARINE POLLUTION BULLETIN

Interactions Between Microorganisms and Marine Microplastics: A Call for Research

(2011) Jesse P. Harrison et al.   MARINE TECHNOLOGY SOCIETY JOURNAL

Environmental and health hazard ranking and assessment of plastic polymers based on chemical composition

(2011) Delilah Lithner et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Bisphenol A impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth

(2010) Alessandro Bolli et al.   IUBMB LIFE

Barrier Capacity of Human Placenta for Nanosized Materials

(2009) Peter Wick et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Within-person variability in urinary bisphenol A concentrations: Measurements from specimens after long-term frozen storage

(2009) Pablo A. Nepomnaschy et al.   ENVIRONMENTAL RESEARCH

Endocrine disruptors in bottled mineral water: total estrogenic burden and migration from plastic bottles

(2009) Martin Wagner et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

International Pellet Watch: Global monitoring of persistent organic pollutants (POPs) in coastal waters. 1. Initial phase data on PCBs, DDTs, and HCHs

(2009) Yuko Ogata et al.   MARINE POLLUTION BULLETIN

Applications and societal benefits of plastics

(2009) A. L. Andrady et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Impact of oral bisphenol A at reference doses on intestinal barrier function and sex differences after perinatal exposure in rats

(2009) V. Braniste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants

(2008) Antonia M. Calafat et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Predicting Plasma Concentrations of Bisphenol A in Children Younger Than 2 Years of Age after Typical Feeding Schedules, using a Physiologically Based Toxicokinetic Model

(2008) Andrea N. Edginton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Maternal and fetal exposure to bisphenol A in Korea

(2008) Young Joo Lee et al.   REPRODUCTIVE TOXICOLOGY