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DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer

Journal

FRONTIERS IN GENETICS
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fgene.2022.823905

Keywords

DNA methylation; gastric cancer; diagnosis; therapy; prognosis

Funding

  1. Key Technology Research and Development Program of Shandong Province [2019GSF108254]

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DNA methylation plays a significant role in the occurrence and development of gastric cancer, and research in this area is crucial for finding cancer biomarkers.
Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence and development are closely related to epigenetic modifications. Methylation of DNA before or during gastric cancer is an interesting research topic. This article reviews the studies on DNA methylation related to the cause, diagnosis, treatment, and prognosis of gastric cancer and aims to find cancer biomarkers to solve major human health problems.

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