Journal
JOURNAL OF BIOPHOTONICS
Volume 10, Issue 2, Pages 217-223Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201600210
Keywords
photoacoustic microscopy; brain imaging; acupuncture
Categories
Funding
- Chinese Government's 1000-Talent Plan via the University of Electronic Science and Technology of China
Ask authors/readers for more resources
Acupuncture has been an effective treatment for various pain in China for several thousand years. However, the mechanisms underlying this mysterious ancient healing are still largely unknown. Here we applied photoacoustic microscopy (PAM) to investigate brain hemodynamic changes in response to electronic acupuncture (EA) at ST36 (Zusanli). Due to the high optical absorption of blood at 532nm, PAM could sensitively probe changes in hemoglobin concentration (HbT, i.e., cerebral blood volume [CBV]) of cortical regions in high resolution. Six healthy mice were stimulated at the acupoint and three healthy mice were stimulated at sham points. Remarkable CBV changes in sensorimotor and retrosplenial agranular cortex were observed. Results showed the potential of PAM as a visualization tool to study the acupuncture effect on brain hemodynamics in animal models.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available