Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis

Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega-oxidation.

(2021) Marta G. Novelle et al.   iScience

Tetraspanin TM4SF5 in hepatocytes negatively modulates SLC27A transporters during acute fatty acid supply

(2021) Dasomi Park et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment

(2021) Eunmi Kim et al.   Cell Reports

Amino acid transporters as tetraspanin TM4SF5 binding partners

(2020) Jae Woo Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Integrated metabolomics and lipidomics reveals high accumulation of polyunsaturated lysoglycerophospholipids in human lung fibroblasts exposed to fine particulate matter

(2020) Jong Cheol Shon et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Differential TM4SF5 ‐mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progression

(2020) Jihye Ryu et al.   JOURNAL OF PATHOLOGY

Organismal Fructose Metabolism in Health and Non-Alcoholic Fatty Liver Disease

(2020) Shea Skenderian et al.   Biology-Basel

Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

(2019) Jae Woo Jung et al.   Cell Metabolism

Recent Insight into the Role of Fibrosis in Nonalcoholic Steatohepatitis-Related Hepatocellular Carcinoma

(2019) Antonio Sircana et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TM4SF5-mediated CD44v8-10 splicing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis

(2019) Ji Eon Kim et al.   Cell Death & Disease

Dietary Fructose Metabolism By Splanchnic Organs: Size Matters

(2018) Javier T. Gonzalez et al.   Cell Metabolism

Fructose metabolism and metabolic disease

(2018) Sarah A. Hannou et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation and fibrosis

(2018) Matthias Mack   MATRIX BIOLOGY

CD133-induced TM4SF5 expression promotes sphere growth via recruitment and blocking of protein tyrosine phosphatase receptor type F (PTPRF)

(2018) Somi Kim et al.   CANCER LETTERS

Advancing the understanding of NAFLD to hepatocellular carcinoma development: From experimental models to humans

(2018) Kan Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments

(2017) Hye-Jin Kim et al.   FASEB JOURNAL

Fructose and NAFLD: The Multifaceted Aspects of  Fructose Metabolism

(2017) Prasanthi Jegatheesan et al.   Nutrients

Effect of fructose consumption on insulin sensitivity in nondiabetic subjects: a systematic review and meta-analysis of diet-intervention trials

(2016) Kasper W ter Horst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

ChREBP regulates fructose-induced glucose production independently of insulin signaling

(2016) Mi-Sung Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis

(2016) Mark A. Herman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Interaction of tetraspan(in) TM4SF5 with CD44 promotes self-renewal and circulating capacities of hepatocarcinoma cells

(2015) Doohyung Lee et al.   HEPATOLOGY

Hepatocytes in liver injury: Victim, bystander, or accomplice in progressive fibrosis?

(2015) Thomas Tu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

TM4SF5-mediated protein-protein networks and tumorigenic roles

(2014) Jung Weon Lee   BMB Reports

Glucose Transporter 8 (GLUT8) Mediates Fructose-inducedde NovoLipogenesis and Macrosteatosis

(2014) Brian J. DeBosch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlations between Transmembrane 4 L6 Family Member 5 (TM4SF5), CD151, and CD63 in Liver Fibrotic Phenotypes and Hepatic Migration and Invasive Capacities

(2014) Minkyung Kang et al.   PLoS One

Fructose metabolism in humans – what isotopic tracer studies tell us

(2012) Sam Z Sun et al.   Nutrition & Metabolism

Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl4-treated mice

(2011) Minkyung Kang et al.   FEBS Journal

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

Modulation of signaling between TM4SF5 and integrins in tumor microenvironment

(2010) Sin-Ae Lee   Frontiers in Bioscience-Landmark

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

GLUT8, the enigmatic intracellular hexose transporter

(2009) Stefan Schmidt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lysosomal localization of GLUT8 in the testis - the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction

(2009) Muhammed Kasim Diril et al.   FEBS Journal

Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes

(2009) María Yáñez-Mó et al.   TRENDS IN CELL BIOLOGY

Cooperation between integrin  5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity

(2008) S. Choi et al.   BLOOD

Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

(2008) Sin-Ae Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

(2008) Vitali Matyash et al.   JOURNAL OF LIPID RESEARCH