QSAR analysis of nicotinamidic compounds and design of potential Bruton’s tyrosine kinase (Btk) inhibitors

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(2016)   IMMUNOLOGICAL REVIEWS

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(2016)   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Ibrutinib (PCI-32765), the First BTK (Bruton’s Tyrosine Kinase) Inhibitor in Clinical Trials

(2013) Jennifer R. Brown   Current Hematologic Malignancy Reports

Molecular Modeling Studies of Piperidine Derivatives as New Acetylcholinesterase Inhibitors against Neurodegenerative Diseases

(2013) Elaine F. F. da Cunha et al.   Journal of Chemistry

Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies

(2012) Yan Lou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rational design of small modified peptides as ACE inhibitors

(2012) Daniel G. Silva et al.   MedChemComm

Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtk 

(2011) E. Janda et al.   BLOOD

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

(2011) S. Ponader et al.   BLOOD

Molecular modeling of the Toxoplasma gondii adenosine kinase inhibitors

(2011) Elaine F. F. da Cunha et al.   MEDICINAL CHEMISTRY RESEARCH

Ligand and structure based pharmacophore modeling to facilitate novel histone deacetylase 8 inhibitor design

(2010) Sundarapandian Thangapandian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

(2010) Julie A Di Paolo et al.   Nature Chemical Biology

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basic validation procedures for regression models in QSAR and QSPR studies: theory and application

(2009) Rudolf Kiralj et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

QSAR Study of Androstenedione Analogs as Aromatase Inhibitors

(2009) Aline Oliveira et al.   Letters in Drug Design & Discovery