Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice

Chronic Exposure to Nanoparticulate TiO2 Causes Renal Fibrosis Involving Activation of the Wnt Pathway in Mouse Kidney

(2015) Fashui Hong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Titanium Nanoparticle Inhalation Induces Renal Fibrosis in Mice via an Oxidative Stress Upregulated Transforming Growth Factor-β Pathway

(2014) Kuo-Tong Huang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Renal Injury and Nrf2 Modulation in Mouse Kidney Following Chronic Exposure to TiO2 Nanoparticles

(2013) Suxin Gui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis

(2013) Benjamin D. Humphreys et al.   JOURNAL OF CLINICAL INVESTIGATION

Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats

(2013) Guangyan Yan et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation

(2012) Hui Yao Lan   International Journal of Biological Sciences

α-SMA Overexpression Associated With Increased Liver Fibrosis in Infants With Biliary Atresia

(2012) Rui Dong et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

TGF-β/Smad Signaling in Kidney Disease

(2012) Hui Y. Lan et al.   SEMINARS IN NEPHROLOGY

Cellular and Molecular Mechanisms of Chronic Inflammation-Associated Organ Fibrosis

(2012) Satoshi Ueha et al.   Frontiers in Immunology

Molecular mechanism of kidney injury of mice caused by exposure to titanium dioxide nanoparticles

(2011) Suxing Gui et al.   JOURNAL OF HAZARDOUS MATERIALS

Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles

(2011) Renping Hu et al.   JOURNAL OF HAZARDOUS MATERIALS

Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model

(2011) Noriyuki Sugiyama et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Vanin-1; a potential biomarker for nephrotoxicant-induced renal injury

(2011) Keiko Hosohata et al.   TOXICOLOGY

Nano-copper induces oxidative stress and apoptosis in kidney via both extrinsic and intrinsic pathways

(2011) Abhijit Sarkar et al.   TOXICOLOGY

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

The mechanism of oxidative damage in the nephrotoxicity of mice caused by nano-anatase TiO2

(2010) Jingfang Zhao et al.   Journal of Experimental Nanoscience

HSP72 Inhibits Smad3 Activation and Nuclear Translocation in Renal Epithelial-to-Mesenchymal Transition

(2010) Y. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanistic connection between inflammation and fibrosis

(2010) Soo Bong Lee et al.   KIDNEY INTERNATIONAL

Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells

(2010) Jie Wu et al.   TOXICOLOGY LETTERS

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Characterizing Manufactured Nanoparticles in the Environment: Multimethod Determination of Particle Sizes

(2009) Rute F. Domingos et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Angiotensin II Induces Connective Tissue Growth Factor and Collagen I Expression via Transforming Growth Factor–β–Dependent and –Independent Smad Pathways

(2009) Fuye Yang et al.   HYPERTENSION

In vivoacute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection

(2009) Jinyuan Chen et al.   JOURNAL OF APPLIED TOXICOLOGY

Advanced Glycation End-Products Induce Tubular CTGF via TGF- -Independent Smad3 Signaling

(2009) A. C.K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

High Doses of Intravenously Administered Titanium Dioxide Nanoparticles Accumulate in the Kidneys of Rainbow Trout but with no Observable Impairment of Renal Function

(2009) Tessa M. Scown et al.   TOXICOLOGICAL SCIENCES

Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells

(2009) Shichang Liu et al.   TOXICOLOGY

Pentoxifylline Inhibits Transforming Growth Factor-Beta Signaling and Renal Fibrosis in Experimental Crescentic Glomerulonephritis in Rats

(2008) Yee-Yung Ng et al.   AMERICAN JOURNAL OF NEPHROLOGY

The Transport of Nanoparticles in Blood Vessels: The Effect of Vessel Permeability and Blood Rheology

(2008) Francesco Gentile et al.   ANNALS OF BIOMEDICAL ENGINEERING

Biochemical Toxicity of Nano-anatase TiO2 Particles in Mice

(2008) Huiting Liu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi

(2008) Enrique Navarro et al.   ECOTOXICOLOGY

Nanotoxicity of TiO2 nanoparticles to erythrocyte in vitro

(2008) Shi-Qiang Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice

(2008) A. C. K. Chung et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Arkadia regulates TGF-β signaling during renal tubular epithelial to mesenchymal cell transition

(2007) F.-Y. Liu et al.   KIDNEY INTERNATIONAL