4.6 Article

Genetics and Sport Injuries: New Perspectives for Athletic Excellence in an Italian Court of Rugby Union Players

Journal

GENES
Volume 13, Issue 6, Pages -

Publisher

MDPI
DOI: 10.3390/genes13060995

Keywords

rugby union; ACE; ACTN3; MCT1; injuries

Funding

  1. Universita Cattolica del Sacro Cuore

Ask authors/readers for more resources

This study investigated the association between ACE, ACTN3, COL1A1, and MCT1 genotypes and injuries in rugby players, and found that the MCT1 AA genotype is associated with the incidence of total and bone injuries. The results highlight the importance of genetic research in developing personalized training and achieving optimal athletic performance.
Several genes are involved in sport performance, especially in injuries incidence. The aim of this study was to investigate the association of ACE, ACTN3, COL1A1, and MCT1 genotypes and injuries in rugby players in order to find a genotype/phenotype correlation and provide useful information improving athletic performance. One-hundred male professional and semiprofessional rugby players were selected. Analysis was performed genotyping the genes ACE, ACTN3, COL1A1, and MCT1 as candidate gene of interest involved in athletic performance. A control group of non-athletic Italian male participants was analyzed to compare the results. We found statistical significance of MCT1 rs1049434 AA for total injuries (chi(2) = 0.115; p = 0.003) and bone injuries (chi(2) = 0.603; p = 0.007) in the rugby athlete population. No statistical significance was found between injury incidence and ACE, ACTN3, COL1A1 genotypes. The MCT1 AA genotype is associated with the incidence of total and bone injuries in the rugby player population. Although environmental factors such as lifestyle, diet, training, and stress can influence athletic performance, our data demonstrated the importance of genetic study in sport aimed at developing personalized training and achieving the best possible athletic excellence.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available