Fixed Airflow Obstruction in Asthma: A Problem of the Whole Lung Not of Just the Airways

Effect of combination inhaled therapy on ventilation distribution measured by SPECT/CT imaging in uncontrolled asthma

(2021) Sandra Rutting et al.   JOURNAL OF APPLIED PHYSIOLOGY

Low FVC/TLC in Preserved Ratio Impaired Spirometry (PRISm) is associated with features of and progression to obstructive lung disease

(2020) Spyridon Fortis et al.   Scientific Reports

Asthma and fixed airflow obstruction: Long‐term trajectories suggest distinct endotypes

(2020) Benjamin M Smith et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults

(2020) Benjamin M. Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Small airway loss in the physiologically ageing lung: a cross-sectional study in unused donor lungs

(2020) Stijn E Verleden et al.   Lancet Respiratory Medicine

Inflammatory patterns in fixed airflow obstruction are dependent on the presence of asthma

(2020) Ida Mogensen et al.   PLoS One

Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP-10 and MET

(2019) Chih-Hsi S. Kuo et al.   ALLERGY

Lung function trajectories in health and disease

(2019) Alvar Agusti et al.   Lancet Respiratory Medicine

Reduced lung elastic recoil and fixed airflow obstruction in asthma

(2019) Katrina O. Tonga et al.   RESPIROLOGY

Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

(2019) Brian L. Graham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Benralizumab efficacy for patients with fixed airflow obstruction and severe, uncontrolled eosinophilic asthma

(2019) Bradley E. Chipps et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study

(2018) Emily S Wan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction

(2018) Arthur F. Gelb et al.   CHEST

Lung elastic recoil and ventilation heterogeneity of diffusion-dependent airways in older people with asthma and fixed airflow obstruction

(2018) Katrina O. Tonga et al.   EUROPEAN RESPIRATORY JOURNAL

Short-term air pollution exposure decreases lung function: a repeated measures study in healthy adults

(2017) Luc Int Panis et al.   Environmental Health

Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial

(2016) J Mark FitzGerald et al.   LANCET

Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma

(2016) Michael J. McGeachie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unsuspected mild emphysema in nonsmoking patients with chronic asthma with persistent airway obstruction

(2013) Arthur F. Gelb et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Respiratory system reactance is an independent determinant of asthma control

(2013) Vanessa J. Kelly et al.   JOURNAL OF APPLIED PHYSIOLOGY

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma

(2012) Catherine E. Farrow et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

Mast cell–associated alveolar inflammation in patients with atopic uncontrolled asthma

(2011) Cecilia K. Andersson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The outer wall of small airways is a major site of remodeling in fatal asthma

(2009) Marisa Dolhnikoff et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Multivariate Analysis of Risk Factors for the Air-Trapping Asthmatic Phenotype as Measured by Quantitative CT Analysis

(2008) Ashley Busacker et al.   CHEST