Iron–sulfur cluster exchange reactions mediated by the human Nfu protein

The Human Iron–Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules

(2015) Nicholas G. Fox et al.   BIOCHEMISTRY

Glutathione-coordinated [2Fe–2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport

(2015) Jingwei Li et al.   CHEMICAL COMMUNICATIONS

NsrR fromStreptomyces coelicolorIs a Nitric Oxide-sensing [4Fe-4S] Cluster Protein with a Specialized Regulatory Function

(2015) Jason C. Crack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical, biochemical, and genetic spectrum of seven patients with NFU1 deficiency

(2015) Uwe Ahting et al.   Frontiers in Genetics

Mitochondrial iron–sulfur protein biogenesis and human disease

(2014) Oliver Stehling et al.   BIOCHIMIE

Fluorescent Probes for Tracking the Transfer of Iron–Sulfur Cluster and Other Metal Cofactors in Biosynthetic Reaction Pathways

(2014) James N. Vranish et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin

(2014) Holger Webert et al.   Nature Communications

Thermodynamic and Structural Analysis of Human NFU Conformational Chemistry

(2013) Jingwei Li et al.   BIOCHEMISTRY

Arabidopsis thaliana Nfu2 Accommodates [2Fe-2S] or [4Fe-4S] Clusters and Is Competent for in Vitro Maturation of Chloroplast [2Fe-2S] and [4Fe-4S] Cluster-Containing Proteins

(2013) Huanyao Gao et al.   BIOCHEMISTRY

Glutathione-complexed iron–sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability

(2013) Wenbin Qi et al.   CHEMICAL COMMUNICATIONS

(IscS-IscU)2Complex Structures Provide Insights into Fe2S2Biogenesis and Transfer

(2012) Elodie N. Marinoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Human ferredoxin-2 displays a unique conformational change

(2012) Wenbin Qi et al.   DALTON TRANSACTIONS

Monothiol glutaredoxins and A-type proteins: partners in Fe–S cluster trafficking

(2012) Daphne T. Mapolelo et al.   DALTON TRANSACTIONS

Protein expression profiles in patients carrying NFU1 mutations. Contribution to the pathophysiology of the disease

(2012) Xènia Ferrer-Cortès et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Separate FeS scaffold and carrier functions for SufB2C2 and SufA during in vitro maturation of [2Fe2S] Fdx

(2012) Harsimranjit K. Chahal et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Glutathione Complexed Fe–S Centers

(2012) Wenbin Qi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monothiol Glutaredoxins Function in Storing and Transporting [Fe2S2] Clusters Assembled on IscU Scaffold Proteins

(2012) Priyanka Shakamuri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular organization, biochemical function, cellular role and evolution of NfuA, an atypical Fe-S carrier

(2012) Béatrice Py et al.   MOLECULAR MICROBIOLOGY

Mutations in Iron-Sulfur Cluster Scaffold Genes NFU1 and BOLA3 Cause a Fatal Deficiency of Multiple Respiratory Chain and 2-Oxoacid Dehydrogenase Enzymes

(2011) Jessie M. Cameron et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Fatal Mitochondrial Disease Is Associated with Defective NFU1 Function in the Maturation of a Subset of Mitochondrial Fe-S Proteins

(2011) Aleix Navarro-Sastre et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease

(2010) Hong Ye et al.   BIOCHEMISTRY

Structural, mechanistic and coordination chemistry of relevance to the biosynthesis of iron–sulfur and related iron cofactors☆

(2010) Wenbin Qi et al.   COORDINATION CHEMISTRY REVIEWS

Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

(2010) A. D. Sheftel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron−Sulfur Cluster Biosynthesis: Functional Characterization of the N- and C-Terminal Domains of Human NFU†

(2009) Yushi Liu et al.   BIOCHEMISTRY

Iron−Sulfur Cluster Biosynthesis: Characterization of a Molten Globule Domain in Human NFU

(2009) Yushi Liu et al.   BIOCHEMISTRY

Characterization of [4Fe-4S]-Containing and Cluster-Free Forms ofStreptomycesWhiD

(2009) Jason C. Crack et al.   BIOCHEMISTRY

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

Chloroplast monothiol glutaredoxins as scaffold proteins for the assembly and delivery of [2Fe–2S] clusters

(2008) Sibali Bandyopadhyay et al.   EMBO JOURNAL

NfuA, a New Factor Required for Maturing Fe/S Proteins inEscherichia coliunder Oxidative Stress and Iron Starvation Conditions

(2008) Sandra Angelini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Proposed Role for theAzotobacter vinelandiiNfuA Protein as an Intermediate Iron-Sulfur Cluster Carrier

(2008) Sibali Bandyopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY