Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library

Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions

(2016) Seymour de Picciotto et al.   JOURNAL OF MOLECULAR BIOLOGY

Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy

(2015) Andreas Plückthun   Annual Review of Pharmacology and Toxicology

Restricted Diversity of Antigen Binding Residues of Antibodies Revealed by Computational Alanine Scanning of 227 Antibody–Antigen Complexes

(2014) Gautier Robin et al.   JOURNAL OF MOLECULAR BIOLOGY

Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold

(2014) John D. Steemson et al.   PLoS One

Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins

(2013) G. Behar et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Directed evolution of proteins for increased stability and expression using yeast display

(2012) Michael W. Traxlmayr et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Design of pH Sensitive Binding Proteins from the Hyperthermophilic Sso7d Scaffold

(2012) Nimish Gera et al.   PLoS One

A Class of Human Proteins that Deliver Functional Proteins into Mammalian Cells In Vitro and In Vivo

(2011) James J. Cronican et al.   CHEMISTRY & BIOLOGY

Highly Stable Binding Proteins Derived from the Hyperthermophilic Sso7d Scaffold

(2011) Nimish Gera et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of Charge on Antibody Tissue Distribution and Pharmacokinetics

(2010) C. Andrew Boswell et al.   BIOCONJUGATE CHEMISTRY

Stability and CDR Composition Biases Enrich Binder Functionality Landscapes

(2010) Benjamin J. Hackel et al.   JOURNAL OF MOLECULAR BIOLOGY

Cystine-knot peptides engineered with specificities for αIIbβ3 or αIIbβ3 and αvβ3 integrins are potent inhibitors of platelet aggregation

(2010) Adam P. Silverman et al.   JOURNAL OF MOLECULAR RECOGNITION

The functional capacity of the natural amino acids for molecular recognition

(2010) Sara Birtalan et al.   Molecular BioSystems

Highly avid magnetic bead capture: An efficient selection method for de novo protein engineering utilizing yeast surface display

(2009) Margaret Ackerman et al.   BIOTECHNOLOGY PROGRESS

Engineered protein scaffolds as next-generation antibody therapeutics

(2009) Michaela Gebauer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

(2009) C Alejandro Velikovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins

(2009) B. R. McNaughton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins

(2009) S. Pechmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interrogating and Predicting Tolerated Sequence Diversity in Protein Folds: Application to E. elaterium Trypsin Inhibitor-II Cystine-Knot Miniprotein

(2009) Jennifer L. Lahti et al.   PLoS Computational Biology

DARPins: A new generation of protein therapeutics

(2008) Michael T. Stumpp et al.   DRUG DISCOVERY TODAY

Alternative binding proteins: Biological activity and therapeutic potential of cystine-knot miniproteins

(2008) Harald Kolmar   FEBS Journal

Alternative binding proteins: Anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities

(2008) Arne Skerra   FEBS Journal

Alternative binding proteins: Affibody binding proteins developed from a small three-helix bundle scaffold

(2008) Per-Åke Nygren   FEBS Journal

The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

(2008) Sara Birtalan et al.   JOURNAL OF MOLECULAR BIOLOGY

A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces

(2008) Ryan N. Gilbreth et al.   JOURNAL OF MOLECULAR BIOLOGY