Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats

MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

(2021) Wei Ying et al.   Cell Metabolism

Transient exposure to miR‐203 enhances the differentiation capacity of established pluripotent stem cells

(2020) María Salazar‐Roa et al.   EMBO JOURNAL

Impaired Bone Regenerative Effect of Exosomes Derived from Bone Marrow Mesenchymal Stem Cells in Type 1 Diabetes

(2019) Yu Zhu et al.   Stem Cells Translational Medicine

Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

(2019) Alexander Rauch et al.   NATURE GENETICS

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis

(2019) Jiangyi Wu et al.   BIOMATERIALS

MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment

(2018) Rongyao Xu et al.   AGING CELL

Feasibility and safety of treating non-unions in tibia, femur and humerus with autologous, expanded, bone marrow-derived mesenchymal stromal cells associated with biphasic calcium phosphate biomaterials in a multicentric, non-comparative trial

(2018) Enrique Gómez-Barrena et al.   BIOMATERIALS

Type 2 diabetes mellitus and bone

(2018) J. Compston   JOURNAL OF INTERNAL MEDICINE

Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma

(2018) Evangelos Terpos et al.   Blood Cancer Journal

Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine – a new paradigm for tissue repair

(2018) I. M. Bjørge et al.   Biomaterials Science

Altered expression of microRNA during fracture healing in diabetic rats

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The Impact of Type 2 Diabetes on Bone Fracture Healing

(2018) Carlos Marin et al.   Frontiers in Endocrinology

Osteoclasts in bone regeneration under type 2 diabetes mellitus

(2018) Zhiai Hu et al.   Acta Biomaterialia

Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis

(2017) Xiaolin Liu et al.   International Journal of Biological Sciences

Type 2 Diabetes and Osteoporosis: A Guide to Optimal Management

(2017) Stavroula Α Paschou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration

(2017) Xiaolin Liu et al.   Nanoscale

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels

(2017) Jagadeesh Gandla et al.   PAIN

MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment

(2017) Wei Seong Toh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis

(2017) Yuqi Guo et al.   Nature Communications

Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts

(2017) Abhijit Deb Roy et al.   Nature Communications

Stem Cell-Derived Extracellular Vesicles as a Novel Potential Therapeutic Tool for Tissue Repair

(2017) Bi Chen et al.   Stem Cells Translational Medicine

Profiling microRNA expression during fracture healing

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Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma

(2016) Ronaldo P. Panganiban et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The roles of bone-derived exosomes and exosomal microRNAs in regulating bone remodelling

(2016) Yong Xie et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

(2016) Defang Li et al.   Nature Communications

Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo

(2016) Yunhao Qin et al.   Scientific Reports

Exosomes: Vehicles of Intercellular Signaling, Biomarkers, and Vectors of Cell Therapy

(2015) Stella Kourembanas   Annual Review of Physiology

BMSCs and hematopoiesis

(2015) Andrés García-García et al.   IMMUNOLOGY LETTERS

Diabetes and Its Effect on Bone and Fracture Healing

(2015) Hongli Jiao et al.   Current Osteoporosis Reports

Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion

(2014) Masakazu Notsu et al.   ENDOCRINOLOGY

Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation

(2012) G. Xu et al.   BLOOD

The linkage between inflammation and Type 2 diabetes mellitus

(2012) Nathália G. Cruz et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

MicroRNAs in the growth plate are responsive to nutritional cues: association between miR-140 and SIRT1

(2012) Rakefet Pando et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Fracture healing under healthy and inflammatory conditions

(2012) Lutz Claes et al.   Nature Reviews Rheumatology

Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function

(2011) Christine Hamann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exosomes From Human CD34 + Stem Cells Mediate Their Proangiogenic Paracrine Activity

(2011) Susmita Sahoo et al.   CIRCULATION RESEARCH

Suppression of bone formation by osteoclastic expression of semaphorin 4D

(2011) Takako Negishi-Koga et al.   NATURE MEDICINE

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

(2011) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells

(2010) Ke Yang et al.   Cardiovascular Diabetology

High Levels of Tumor Necrosis Factor-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing

(2009) Jazia Alblowi et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNA hsa-miR-135b Regulates Mineralization in Osteogenic Differentiation of Human Unrestricted Somatic Stem Cells

(2009) Aneta M. Schaap-Oziemlak et al.   STEM CELLS AND DEVELOPMENT

A microRNA signature for a BMP2-induced osteoblast lineage commitment program

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA