Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

(2016) Ruhma Syeda et al.   CELL

VRACs and other ion channels and transporters in the regulation of cell volume and beyond

(2016) Thomas J. Jentsch   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The identification of a volume-regulated anion channel: an amazing Odyssey

(2015) S. F. Pedersen et al.   Acta Physiologica

VRACs swallow platinum drugs

(2015) T. Voets et al.   EMBO JOURNAL

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs

(2015) R. Planells-Cases et al.   EMBO JOURNAL

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel

(2014) Zhaozhu Qiu et al.   CELL

The Protein Synthesis Inhibitor Blasticidin S Enters Mammalian Cells via Leucine-rich Repeat-containing Protein 8D

(2014) Clarissa C. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function

(2014) Lalit Kumar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC

(2014) F. K. Voss et al.   SCIENCE

LRRC8 proteins share a common ancestor with pannexins, and may form hexameric channels involved in cell-cell communication

(2012) Federico Abascal et al.   BIOESSAYS

Alanine substitution scanning of pannexin1 reveals amino acid residues mediating ATP sensitivity

(2011) Feng Qiu et al.   Purinergic Signalling

SCAM analysis of Panx1 suggests a peculiar pore structure

(2010) Junjie Wang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Structural mechanism of C-type inactivation in K+ channels

(2010) Luis G. Cuello et al.   NATURE

Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel

(2009) Yasunobu Okada et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

(2009) Shoji Maeda et al.   NATURE

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS