Heat Shock Protein 90 Modulates Lipid Homeostasis by Regulating the Stability and Function of Sterol Regulatory Element-binding Protein (SREBP) and SREBP Cleavage-activating Protein

Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization

(2016) Xin Gong et al.   CELL RESEARCH

Direct Demonstration That Loop1 of Scap Binds to Loop7

(2016) Yinxin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth

(2016) Peng Ru et al.   Cell Reports

Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth

(2015) Chunming Cheng et al.   CANCER CELL

Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation

(2015) Shingo Miyata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Hsp90 in urothelial carcinoma

(2015) Mahmoud Chehab et al.   Oncotarget

Targeting Heat-Shock Protein 90 (HSP90) as a Complementary Strategy to Immune Checkpoint Blockade for Cancer Therapy

(2015) D. A. Proia et al.   Cancer Immunology Research

Heat shock proteins in multiple myeloma

(2015) Lei Zhang et al.   Oncotarget

Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)

(2014) Wei Shao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury

(2014) Aditya Ambade et al.   JOURNAL OF HEPATOLOGY

Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease

(2014) Matthew C. Wheeler et al.   JOURNAL OF LIPID RESEARCH

Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors

(2014) Rohit Bhat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hsp90 chaperones PPARγ and regulates differentiation and survival of 3T3-L1 adipocytes

(2013) M T Nguyen et al.   CELL DEATH AND DIFFERENTIATION

Point Mutation in Luminal Loop 7 of Scap Protein Blocks Interaction with Loop 1 and Abolishes Movement to Golgi

(2013) Yinxin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp70 and Hsp90 Multichaperone Complexes Sequentially Regulate Thiazide-sensitive Cotransporter Endoplasmic Reticulum-associated Degradation and Biogenesis

(2013) Bridget F. Donnelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

(2012) Mikko Taipale et al.   CELL

Evolution and function of diverse Hsp90 homologs and cochaperone proteins

(2011) Jill L. Johnson   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of Cholesterol and Fatty Acid Synthesis

(2011) J. Ye et al.   Cold Spring Harbor Perspectives in Biology

The Hop/Sti1-Hsp90 Chaperone Complex Facilitates the Maturation and Transport of a PAMP Receptor in Rice Innate Immunity

(2010) Letian Chen et al.   Cell Host & Microbe

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Coordination of Lipid Metabolism in Membrane Biogenesis

(2009) Axel Nohturfft et al.   Annual Review of Cell and Developmental Biology

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY