Protein-Protein Interactions, Not Substrate Recognition, Dominate the Turnover of Chimeric Assembly Line Polyketide Synthases

Structure and mechanism of assembly line polyketide synthases

(2016) Thomas Robbins et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases

(2016) Matthew P Ostrowski et al.   JOURNAL OF ANTIBIOTICS

A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases

(2016) Brian Lowry et al.   ACS Central Science

Assembly Line Polyketide Synthases: Mechanistic Insights and Unsolved Problems

(2014) Chaitan Khosla et al.   BIOCHEMISTRY

Stereochemistry of Reductions Catalyzed by Methyl-Epimerizing Ketoreductase Domains of Polyketide Synthases

(2013) Young-Ok You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vitro Reconstitution and Analysis of the 6-Deoxyerythronolide B Synthase

(2013) Brian Lowry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation

(2012) S. Kapur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymatic Extender Unit Generation for In Vitro Polyketide Synthase Reactions: Structural and Func-tional Showcasing of Streptomyces coelicolor MatB

(2011) Amanda J. Hughes et al.   CHEMISTRY & BIOLOGY

Biosynthesis of rapamycin and its regulation: past achievements and recent progress

(2010) Sung Ryeol Park et al.   JOURNAL OF ANTIBIOTICS

Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

(2010) S. Kapur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking Domains

(2009) Tonia J. Buchholz et al.   ACS Chemical Biology