Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis

Complexes of Amyloid-β and Cystatin C in the Human Central Nervous System

(2017) Weiqian Mi et al.   JOURNAL OF ALZHEIMERS DISEASE

Accumulated Amyloid-β Peptide and Hyperphosphorylated Tau Protein: Relationship and Links in Alzheimer's Disease

(2017) Han-Chang Huang et al.   JOURNAL OF ALZHEIMERS DISEASE

Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-β Production

(2017) Emma H. Gray et al.   JOURNAL OF ALZHEIMERS DISEASE

Prion Protein is Reduced in Aging and in Sporadic but not in Familial Alzheimer's Disease

(2017) Isobel J. Whitehouse et al.   JOURNAL OF ALZHEIMERS DISEASE

Cystatin C Protects Neuronal Cells from Amyloid-β-induced Toxicity

(2017) Belen Tizon et al.   JOURNAL OF ALZHEIMERS DISEASE

Reciprocal Molecular Interactions between the Aβ Peptide Linked to Alzheimer’s Disease and Insulin Linked to Diabetes Mellitus Type II

(2016) Jinghui Luo et al.   ACS Chemical Neuroscience

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer⿿s disease

(2016) Cecilia Wallin et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Amyloid and tau pathology of familial Alzheimer’s disease APP/PS1 mouse model in a senescence phenotype background (SAMP8)

(2015) D. Porquet et al.   AGE

Antibody drugs for Alzheimer’s show glimmers of promise

(2015) Sara Reardon   NATURE

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

(2015) Zane Jaunmuktane et al.   NATURE

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease

(2015) Linda Helmfors et al.   NEUROBIOLOGY OF DISEASE

Alzheimer Peptides Aggregate into Transient Nanoglobules That Nucleate Fibrils

(2014) Jinghui Luo et al.   BIOCHEMISTRY

Endogenous Polyamines Reduce the Toxicity of Soluble Aβ Peptide Aggregates Associated with Alzheimer’s Disease

(2014) Jinghui Luo et al.   BIOMACROMOLECULES

Cyclic Peptides as Inhibitors of Amyloid Fibrillation

(2014) Jinghui Luo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Non-chaperone Proteins Can Inhibit Aggregation and Cytotoxicity of Alzheimer Amyloid β Peptide

(2014) Jinghui Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway

(2014) Axel Abelein et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells

(2014) Benjamin Ettle et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Aβ peptide forms non-amyloid fibrils in the presence of carbon nanotubes

(2014) Jinghui Luo et al.   Nanoscale

Extracellular α-synuclein—a novel and crucial factor in Lewy body diseases

(2014) He-Jin Lee et al.   Nature Reviews Neurology

Cellular Polyamines Promote Amyloid-Beta (Aβ) Peptide Fibrillation and Modulate the Aggregation Pathways

(2013) Jinghui Luo et al.   ACS Chemical Neuroscience

Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40

(2013) Li-Mei Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Biophysical Studies of the Amyloid β-Peptide: Interactions with Metal Ions and Small Molecules

(2013) Sebastian Wärmländer et al.   CHEMBIOCHEM

Human lysozyme inhibits the in vitro aggregation of Aβ peptides, which in vivo are associated with Alzheimer's disease

(2013) Jinghui Luo et al.   CHEMICAL COMMUNICATIONS

Inhibiting and Reversing Amyloid-β Peptide (1-40) Fibril Formation with Gramicidin S and Engineered Analogues

(2013) Jinghui Luo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity

(2013) Ping Cao et al.   FEBS LETTERS

An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicityin Vivo

(2013) Brian R. Fluharty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cu2+ Affects Amyloid-β (1–42) Aggregation by Increasing Peptide-Peptide Binding Forces

(2013) Francis Hane et al.   PLoS One

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

(2013) Andrew J. Nicoll et al.   Nature Communications

Proteolytic Degradation of Amyloid  -Protein

(2013) T. Saido et al.   Cold Spring Harbor Perspectives in Medicine

Familial Alzheimer’s Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization

(2012) Megan Murray Gessel et al.   ACS Chemical Neuroscience

Pathologic Accumulation of α-Synuclein and Aβ in Parkinson Disease Patients With Dementia

(2012) Paul T. Kotzbauer et al.   ARCHIVES OF NEUROLOGY

Transthyretin (TTR) Cardiac Amyloidosis

(2012) Frederick L. Ruberg et al.   CIRCULATION

Cathepsin B Degrades Amyloid-β in Mice Expressing Wild-type Human Amyloid Precursor Protein

(2012) Chao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Prion Protein Inhibits Amyloid-β (Aβ) Fibrillization and Toxicity

(2012) Krzysztof Nieznanski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons

(2012) Gui-Zhi Yang et al.   JOURNAL OF NEUROCHEMISTRY

Cross-seeding effects of amyloid β-protein and α-synuclein

(2012) Kenjiro Ono et al.   JOURNAL OF NEUROCHEMISTRY

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria

(2012) Lihi Adler-Abramovich et al.   Nature Chemical Biology

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

(2012) Pin-Nan Cheng et al.   Nature Chemistry

Identification of beta-amyloid-binding sites on transthyretin

(2012) J. Du et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Cystatin C in Alzheimer's disease

(2012) Gurjinder Kaur et al.   Frontiers in Molecular Neuroscience

Amyloid-β42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain

(2011) Wen-Quan Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?

(2011) Xinyi Li et al.   Molecular Neurodegeneration

AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation

(2011) Xiao-Hong Li et al.   NEUROBIOLOGY OF AGING

Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association

(2010) Erika Andreetto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overexpression of Human Apolipoprotein A-I Preserves Cognitive Function and Attenuates Neuroinflammation and Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer Disease

(2010) Terry L. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer's and Prion Diseases

(2010) R. Morales et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Alzheimer's disease peptide  -amyloid interacts with fibrinogen and induces its oligomerization

(2010) H. J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

(2008) Dick Terwel et al.   AMERICAN JOURNAL OF PATHOLOGY

Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity

(2008) R. Costa et al.   FEBS LETTERS

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL