Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart

The structural basis for specificity in lipoxygenase catalysis

(2015) Marcia E. Newcomer et al.   PROTEIN SCIENCE

An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis

(2014) Jana Gerstmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Arachidonic Acid Metabolome Serves as a Conserved Regulator of Cholesterol Metabolism

(2014) Egon Demetz et al.   Cell Metabolism

ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation

(2014) Sivareddy Kotla et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Structure of Human 15-Lipoxygenase-2 with a Substrate Mimic

(2014) Matthew J. Kobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of a Lipoxygenase in Complex with Substrate

(2014) David B. Neau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Site-Directed Mutagenesis of Catalytic Residues in N5-Carboxyaminoimidazole Ribonucleotide Synthetase

(2013) Mahender B. Dewal et al.   BIOCHEMISTRY

Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa

(2013) Albert Garreta et al.   FASEB JOURNAL

The Transcription Factor CREB Enhances Interleukin-17A Production and Inflammation in a Mouse Model of Atherosclerosis

(2013) S. Kotla et al.   Science Signaling

Animal Models of Atherosclerosis

(2012) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesteryl ester acyl oxidation and remodeling in murine macrophages: formation of oxidized phosphatidylcholine

(2012) Patrick M. Hutchins et al.   JOURNAL OF LIPID RESEARCH

Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis

(2012) Lisa U. Magnusson et al.   PLoS One

Crystal Structure of 12-Lipoxygenase Catalytic-Domain-Inhibitor Complex Identifies a Substrate-Binding Channel for Catalysis

(2012) Shu Xu et al.   STRUCTURE

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation

(2010) Christopher P. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipidomics reveals a remarkable diversity of lipids in human plasma,

(2010) Oswald Quehenberger et al.   JOURNAL OF LIPID RESEARCH

A new bioinformatics analysis tools framework at EMBL-EBI

(2010) M. Goujon et al.   NUCLEIC ACIDS RESEARCH