Constitutive Endocytosis of VEGFR2 Protects the Receptor against Shedding

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8

(2015) Gina A. Smith et al.   TRAFFIC

Stealing VEGF from Thy Neighbor

(2014) Courtney K. Domigan et al.   CELL

News from the caves: update on the structure and function of caveolae

(2014) Elena Shvets et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

(2014) M. Y. Lee et al.   DEVELOPMENT

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

Thioredoxin-Interacting Protein Mediates Sustained VEGFR2 Signaling in Endothelial Cells Required for Angiogenesis

(2013) Shin-Young Park et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic Reduction of Vascular Endothelial Growth Factor Receptor 2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency

(2013) Kandice L. Tessneer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endocytic Rabs in membrane trafficking and signaling

(2013) Johannes Numrich et al.   BIOLOGICAL CHEMISTRY

Essential Role for Endocytosis in the Growth Factor-stimulated Activation of ERK1/2 in Endothelial Cells

(2013) Morgane Gourlaouen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of Cdc42 Enhances ADAM17-Mediated Vascular Endothelial Growth Factor Receptor 2 Shedding and Impairs Vascular Endothelial Cell Survival and Vasculogenesis

(2013) Y. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

Spatial regulation of VEGF receptor endocytosis in angiogenesis

(2013) Masanori Nakayama et al.   NATURE CELL BIOLOGY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clathrin and post-Golgi trafficking: a very complicated issue

(2013) David G. Robinson et al.   TRENDS IN PLANT SCIENCE

Endocytosis of Receptor Tyrosine Kinases

(2013) L. K. Goh et al.   Cold Spring Harbor Perspectives in Biology

Monoubiquitination of pro-amphiregulin regulates its endocytosis and ectodomain shedding

(2012) Shinji Fukuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A complete Rab screening reveals novel insights in Weibel-Palade body exocytosis

(2012) S. Zografou et al.   JOURNAL OF CELL SCIENCE

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling

(2012) Satish Pasula et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan

(2012) Sara Sigismund et al.   PHYSIOLOGICAL REVIEWS

A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair

(2012) Alexander F. Bruns et al.   PLoS One

Dynamin: Functional Design of a Membrane Fission Catalyst

(2011) Sandra L. Schmid et al.   Annual Review of Cell and Developmental Biology

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling

(2011) Helen M. Jopling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Molecular control of endothelial cell behaviour during blood vessel morphogenesis

(2011) Shane P. Herbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD39 Reveals Novel Insights into the Role of Transmembrane Domains in Protein Processing, Apical Targeting and Activity

(2011) Agathi Papanikolaou et al.   TRAFFIC

A Disintegrin and Metalloprotease 10 Is a Novel Mediator of Vascular Endothelial Growth Factor–Induced Endothelial Cell Function in Angiogenesis and Is Associated With Atherosclerosis

(2010) Marjo M.P.C. Donners et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

(2010) Suphansa Sawamiphak et al.   NATURE

Proteolytic processing of protocadherin proteins requires endocytosis

(2010) Sean M. Buchanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive Endocytosis of the Chemokine CX3CL1 Prevents Its Degradation by Cell Surface Metalloproteases

(2009) Yi-Wei Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth

(2009) Romulo J C Albuquerque et al.   NATURE MEDICINE

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis

(2009) Alexander F. Bruns et al.   TRAFFIC

VEGF-A Stimulates ADAM17-Dependent Shedding of VEGFR2 and Crosstalk Between VEGFR2 and ERK Signaling

(2008) Steven Swendeman et al.   CIRCULATION RESEARCH