Identification of Hepatic Lysophosphatidylcholine Acyltransferase 3 as a Novel Target Gene Regulated by Peroxisome Proliferator-activated Receptor δ

SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expressionin Vivoandin Vitrothrough a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter

(2016) Amar Bahadur Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver-specific overexpression of LPCAT3 reduces postprandial hyperglycemia and improves lipoprotein metabolic profile in mice

(2016) J G Cash et al.   Nutrition & Diabetes

A novel peroxisome proliferator response element modulates hepatic low-density lipoprotein receptor gene transcription in response to PPAR  activation

(2015) V. R. Shende et al.   BIOCHEMICAL JOURNAL

PPAR-β/δ activation promotes phospholipid transfer protein expression

(2015) Khouloud Chehaibi et al.   BIOCHEMICAL PHARMACOLOGY

PPARδ activation induces hepatic long-chain acyl-CoA synthetase 4 expression in vivo and in vitro

(2015) Chin Fung Kelvin Kan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation

(2015) Xiaowei Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

(2015) Xin Rong et al.   eLife

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport

(2015) Tomomi Hashidate-Yoshida et al.   eLife

Acyl-CoA Metabolism and Partitioning

(2014) Trisha J. Grevengoed et al.   Annual Review of Nutrition

CETP inhibitors downregulate hepatic LDL receptor and PCSK9 expression in vitro and in vivo through a SREBP2 dependent mechanism

(2014) Bin Dong et al.   ATHEROSCLEROSIS

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

(2014) Laia Salvadó et al.   DIABETOLOGIA

PPARδ activation attenuates hepatic steatosis inLdlr−/−mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

(2014) Lazar A. Bojic et al.   JOURNAL OF LIPID RESEARCH

Liver X Receptor Regulates Arachidonic Acid Distribution and Eicosanoid Release in Human Macrophages

(2013) Minako Ishibashi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of long-chain acyl-coenzyme A synthetases in the regulation of arachidonic acid metabolism in interleukin 1β-stimulated rat fibroblasts

(2013) Hiroshi Kuwata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol

(2013) Eva-Maria Küch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates

(2013) Mónica Lopes-Marques et al.   BMC EVOLUTIONARY BIOLOGY

LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition

(2013) Xin Rong et al.   Cell Metabolism

High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway

(2013) Bin Dong et al.   JOURNAL OF LIPID RESEARCH

Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung

(2013) Jun Yang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use

(2013) Sihao Liu et al.   NATURE

Acyltransferases and transacylases that determine the fatty acid composition of glycerolipids and the metabolism of bioactive lipid mediators in mammalian cells and model organisms

(2013) Atsushi Yamashita et al.   PROGRESS IN LIPID RESEARCH

Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus

(2012) Laia Salvadó et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Influence of chronic stress on the compositions of hepatic cholesterol and triglyceride in male Wistar rats fed a high fat diet

(2012) Siyuan Gao et al.   HEPATOLOGY RESEARCH

Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment

(2012) Teresa Ramirez et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Role of Peroxisome Proliferator-activated Receptor δ/β in Hepatic Metabolic Regulation

(2010) Sihao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long Chain Acyl-CoA Synthetase-3 Is a Molecular Target for Peroxisome Proliferator-activated Receptor δ in HepG2 Hepatoma Cells

(2010) Aiqin Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-Activated Receptor (PPAR)β /δ: A New Potential Therapeutic Target for the Treatment of Metabolic Syndrome

(2010) Teresa Coll et al.   Current Molecular Pharmacology

Future Challenges for Microsomal Transport Protein Inhibitors

(2009) Anthony Wierzbicki et al.   Current Vascular Pharmacology

Peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) acts as regulator of metabolism linked to multiple cellular functions

(2009) Kay-Dietrich Wagner et al.   PHARMACOLOGY & THERAPEUTICS

Mammalian Long-Chain Acyl-CoA Synthetases

(2008) Eric Soupene et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Identification and Characterization of a Major Liver Lysophosphatidylcholine Acyltransferase

(2008) Yang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY