Complement Membrane Attack and Tumorigenesis

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

The role of complement in mAb-based therapies of cancer

(2013) Ronald P. Taylor et al.   METHODS

Complement inhibition in cancer therapy

(2013) Ruben Pio et al.   SEMINARS IN IMMUNOLOGY

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Sublytic C5b-9 Complexes Induce Apoptosis of Glomerular Mesangial Cells in Rats with Thy-1 Nephritis through Role of Interferon Regulatory Factor-1-dependent Caspase 8 Activation

(2012) Lisha Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix Metalloproteinase-13 (MMP-13) Directly and Indirectly Promotes Tumor Angiogenesis

(2012) Yasusei Kudo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anaphylatoxin C5a Creates a Favorable Microenvironment for Lung Cancer Progression

(2012) Leticia Corrales et al.   JOURNAL OF IMMUNOLOGY

Opposing Roles for Complement Component C5a in Tumor Progression and the Tumor Microenvironment

(2012) L. Gunn et al.   JOURNAL OF IMMUNOLOGY

The Early Growth Response Gene Egr2 (Alias Krox20) Is a Novel Transcriptional Target of Transforming Growth Factor-β that Is Up-Regulated in Systemic Sclerosis and Mediates Profibrotic Responses

(2011) Feng Fang et al.   AMERICAN JOURNAL OF PATHOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration

(2011) K Lueck et al.   EYE

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor

(2010) Christine Bolitho et al.   ENDOCRINE-RELATED CANCER

EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin

(2010) Joerg Kumbrink et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cancer and the Complement Cascade

(2010) M. J. Rutkowski et al.   MOLECULAR CANCER RESEARCH

Unwelcome Complement

(2009) M. M. Markiewski et al.   CANCER RESEARCH

Chemokine CXCL1/KC and its Receptor CXCR2 Are Responsible for Neutrophil Chemotaxis in Adenoviral Keratitis

(2009) Ashish V. Chintakuntlawar et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Is complement good or bad for cancer patients? A new perspective on an old dilemma

(2009) Maciej M. Markiewski et al.   TRENDS IN IMMUNOLOGY

ELR+ CXC chemokine expression in benign and malignant colorectal conditions

(2008) Claudia Rubie et al.   BMC CANCER

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY