Destination and Specific Impact of Different Bile Acids in the Intestinal Pathogen Clostridioides difficile

A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δerm

(2021) Daniel Troitzsch et al.   mSphere

Non-invasive and label-free 3D-visualization shows in vivo oligomerization of the staphylococcal alkaline shock protein 23 (Asp23)

(2020) Inga Petersen et al.   Scientific Reports

Differential View on the Bile Acid Stress Response of Clostridioides difficile

(2019) Susanne Sievers et al.   Frontiers in Microbiology

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile

(2019) Thomas Dubois et al.   npj Biofilms and Microbiomes

Comprehensive Redox Profiling of the Thiol Proteome ofClostridium difficile

(2018) Susanne Sievers et al.   MOLECULAR & CELLULAR PROTEOMICS

A genetic switch controls the production of flagella and toxins in Clostridium difficile

(2017) Brandon R. Anjuwon-Foster et al.   PLoS Genetics

Bile acid sensitivity and in vivo virulence of clinical Clostridium difficile isolates

(2016) Brittany B. Lewis et al.   ANAEROBE

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

(2016) Jenessa A. Winston et al.   ANAEROBE

The Regulatory Networks That Control Clostridium difficile Toxin Synthesis

(2016) Isabelle Martin-Verstraete et al.   Toxins

MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

(2016) Ernesto S. Nakayasu et al.   mSystems

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth

(2016) Alexa R. Weingarden et al.   PLoS One

Interactions Between the Gastrointestinal Microbiome and Clostridium difficile

(2015) Casey M. Theriot et al.   Annual Review of Microbiology

Integration of metabolism and virulence in Clostridium difficile

(2015) Laurent Bouillaut et al.   RESEARCH IN MICROBIOLOGY

The role of flagella in Clostridium difficile pathogenicity

(2015) Emma Stevenson et al.   TRENDS IN MICROBIOLOGY

Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders

(2015) Stefano Fiorucci et al.   TRENDS IN MOLECULAR MEDICINE

Clostridium difficile contains plasmalogen species of phospholipids and glycolipids

(2014) Ziqiang Guan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fecal Microbiota Transplantation for the Treatment of Clostridium difficile Infection

(2014) Giovanni Cammarota et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Bile Acids Modulate Signaling by Functional Perturbation of Plasma Membrane Domains

(2013) Yong Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Flagella in Clostridium difficile Pathogenesis: Comparison between a Non-Epidemic and an Epidemic Strain

(2013) Soza T. Baban et al.   PLoS One

Bile Salt Inhibition of Host Cell Damage by Clostridium Difficile Toxins

(2013) Charles Darkoh et al.   PLoS One

Characterization of the SigD Regulon of C. difficile and Its Positive Control of Toxin Production through the Regulation of tcdR

(2013) Imane El Meouche et al.   PLoS One

Genome-Wide Identification of Regulatory RNAs in the Human Pathogen Clostridium difficile

(2013) Olga A. Soutourina et al.   PLoS Genetics

Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

(2013) Michael B. Francis et al.   PLoS Pathogens

Modulation of Toxin Production by the Flagellar Regulon in Clostridium difficile

(2012) Annie Aubry et al.   INFECTION AND IMMUNITY

Clostridium difficile flagellin stimulates toll-like receptor 5, and toxin B promotes flagellin-induced chemokine production via TLR5

(2012) Yusuke Yoshino et al.   LIFE SCIENCES

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis

(2012) P. Nicolas et al.   SCIENCE

Good Caco-2 cell culture practices

(2012) Manuela Natoli et al.   TOXICOLOGY IN VITRO

Protection from Clostridium difficile toxin B-catalysed Rac1/Cdc42 glucosylation by tauroursodeoxycholic acid-induced Rac1/Cdc42 phosphorylation

(2011) Vanessa Brandes et al.   BIOLOGICAL CHEMISTRY

Mutagenic Analysis of the Clostridium difficile Flagellar Proteins, FliC and FliD, and Their Contribution to Virulence in Hamsters

(2011) Tanis C. Dingle et al.   INFECTION AND IMMUNITY

Functional microdomains in bacterial membranes

(2010) D. Lopez et al.   GENES & DEVELOPMENT

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

The enterohepatic circulation of bile acids in mammals: form and functions

(2009) Alan et al.   Frontiers in Bioscience-Landmark

Motility and Flagellar Glycosylation in Clostridium difficile

(2009) S. M. Twine et al.   JOURNAL OF BACTERIOLOGY

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

(2008) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY