Phospholipase Cγ1 (PLCγ1) Controls Osteoclast Numbers via Colony-stimulating Factor 1 (CSF-1)-dependent Diacylglycerol/β-Catenin/CyclinD1 Pathway

Diacylglycerol Kinase ζ (DGKζ) Is a Critical Regulator of Bone Homeostasis Via Modulation of c-Fos Levels in Osteoclasts

(2015) Ali Zamani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1

(2015) Yongwei Zheng et al.   PLoS One

Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass

(2015) Corinne E. Decker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunction of phospholipase Cγ in immune disorders and cancer

(2014) Hans Koss et al.   TRENDS IN BIOCHEMICAL SCIENCES

Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

(2013) Joachim Albers et al.   JOURNAL OF CELL BIOLOGY

PPARβ/δ governs Wnt signaling and bone turnover

(2013) Carina Scholtysek et al.   NATURE MEDICINE

The WNT signaling pathway from ligand secretion to gene transcription: Molecular mechanisms and pharmacological targets

(2013) Hoeke A. Baarsma et al.   PHARMACOLOGY & THERAPEUTICS

TREM2 and  -Catenin Regulate Bone Homeostasis by Controlling the Rate of Osteoclastogenesis

(2012) K. Otero et al.   JOURNAL OF IMMUNOLOGY

Roles of Wnt signals in bone resorption during physiological and pathological states

(2012) Kazuhiro Maeda et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Phospholipase Cγ-2 and Intracellular Calcium Are Required for Lipopolysaccharide-induced Toll-like Receptor 4 (TLR4) Endocytosis and Interferon Regulatory Factor 3 (IRF3) Activation

(2011) Chih-Yuan Chiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by  -Catenin

(2011) W. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

PLCγ2: where bone and immune cells find their common ground

(2010) Roberta Faccio et al.   Annals of the New York Academy of Sciences

Phospholipase Cγ1 is essential for T cell development, activation, and tolerance

(2010) Guoping Fu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phospholipase C Gamma 2 Is Critical for Development of a Murine Model of Inflammatory Arthritis by Affecting Actin Dynamics in Dendritic Cells

(2010) Viviana Cremasco et al.   PLoS One

PLC regulation: emerging pictures for molecular mechanisms

(2010) Tom D. Bunney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Osteoclast motility: Putting the brakes on bone resorption

(2009) Deborah V. Novack et al.   AGEING RESEARCH REVIEWS

Characterization of Wnt/β-catenin signalling in osteoclasts in multiple myeloma

(2009) Ya-Wei Qiang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

(2009) Karel Otero et al.   NATURE IMMUNOLOGY

Vav/Phospholipase Cγ2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis

(2008) Viviana Cremasco et al.   ARTHRITIS AND RHEUMATISM

Phospholipase C 2 is necessary for separation of blood and lymphatic vasculature in mice

(2008) H. Ichise et al.   DEVELOPMENT

Phospholipase Cγ2 Mediates RANKL-stimulated Lymph Node Organogenesis and Osteoclastogenesis

(2008) Yabing Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase C 2 Modulates Integrin Signaling in the Osteoclast by Affecting the Localization and Activation of Src Kinase

(2008) H. Epple et al.   MOLECULAR AND CELLULAR BIOLOGY