Associative learning drives longitudinally graded presynaptic plasticity of neurotransmitter release along axonal compartments

Mushroom body output differentiates memory processes and distinct memory-guided behaviors

(2021) Toshiharu Ichinose et al.   CURRENT BIOLOGY

Transsynaptic mapping of Drosophila mushroom body output neurons

(2021) Kristin M Scaplen et al.   eLife

The Drosophila ortholog of the schizophrenia-associated CACNA1A and CACNA1B voltage-gated calcium channels regulate memory, sleep and circadian rhythms

(2021) Sergio Hidalgo et al.   NEUROBIOLOGY OF DISEASE

Learning with reinforcement prediction errors in a model of the Drosophila mushroom body

(2021) James E. M. Bennett et al.   Nature Communications

A mechanistic model for reward prediction and extinction learning in the fruit fly

(2021) Magdalena Springer et al.   eNeuro

Models of heterogeneous dopamine signaling in an insect learning and memory center

(2021) Linnie Jiang et al.   PLoS Computational Biology

Compensatory variability in network parameters enhances memory performance in the Drosophila mushroom body

(2021) Nada Y. Abdelrahman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit

(2020) Mehrab N. Modi et al.   Annual Review of Neuroscience

Spaced Training Forms Complementary Long-Term Memories of Opposite Valence in Drosophila

(2020) Pedro F. Jacob et al.   NEURON

Visualization of a Distributed Synaptic Memory Code in the Drosophila Brain

(2020) Florian Bilz et al.   NEURON

Input Connectivity Reveals Additional Heterogeneity of Dopaminergic Reinforcement in Drosophila

(2020) Nils Otto et al.   CURRENT BIOLOGY

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

(2020) Miao Jing et al.   NATURE METHODS

A connectome and analysis of the adult Drosophila central brain

(2020) Louis K Scheffer et al.   eLife

The connectome of the adult Drosophila mushroom body provides insights into function

(2020) Feng Li et al.   eLife

Suppression of GABAergic neurons through D2-like receptor secures efficient conditioning in Drosophila aversive olfactory learning

(2019) Mingmin Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous tagging reveals differential regulation of Ca2+ channels at single AZs during presynaptic homeostatic potentiation and depression

(2019) Scott J. Gratz et al.   JOURNAL OF NEUROSCIENCE

Independent Contributions of Discrete Dopaminergic Circuits to Cellular Plasticity, Memory Strength, and Valence in Drosophila

(2019) Tamara Boto et al.   Cell Reports

Distinct Dopamine Receptor Pathways Underlie the Temporal Sensitivity of Associative Learning

(2019) Annie Handler et al.   CELL

Maintenance of homeostatic plasticity at the Drosophila neuromuscular synapse requires continuous IP3-directed signaling

(2019) Thomas D James et al.   eLife

Inhibitory muscarinic acetylcholine receptors enhance aversive olfactory learning in adult Drosophila

(2019) Noa Bielopolski et al.   eLife

Aversive Training Induces Both Pre- and Postsynaptic Suppression in Drosophila

(2019) Xiaofan Zhang et al.   JOURNAL OF NEUROSCIENCE

A Neural Circuit Arbitrates between Persistence and Withdrawal in Hungry Drosophila

(2019) Sercan Sayin et al.   NEURON

Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

(2019) Yoshinori Aso et al.   eLife

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies

(2018) Miao Jing et al.   NATURE BIOTECHNOLOGY

Persistent activity in a recurrent circuit underlies courtship memory in Drosophila

(2018) Xiaoliang Zhao et al.   eLife

CaV2.1 α1 Subunit Expression Regulates Presynaptic CaV2.1 Abundance and Synaptic Strength at a Central Synapse

(2018) Matthias Lübbert et al.   NEURON

Dopamine Neurons Mediate Learning and Forgetting through Bidirectional Modulation of a Memory Trace

(2018) Jacob A. Berry et al.   Cell Reports

Cyclic AMP-dependent plasticity underlies rapid changes in odor coding associated with reward learning

(2017) Thierry Louis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reciprocal synapses between mushroom body and dopamine neurons form a positive feedback loop required for learning

(2017) Isaac Cervantes-Sandoval et al.   eLife

A connectome of a learning and memory center in the adult Drosophila brain

(2017) Shin-ya Takemura et al.   eLife

Long-term memory requires sequential protein synthesis in three subsets of mushroom body output neurons in Drosophila

(2017) Jie-Kai Wu et al.   Scientific Reports

Synapse-Level Determination of Action Potential Duration by K + Channel Clustering in Axons

(2016) Matthew J.M. Rowan et al.   NEURON

Aversive Learning and Appetitive Motivation Toggle Feed-Forward Inhibition in the Drosophila Mushroom Body

(2016) Emmanuel Perisse et al.   NEURON

Memory-Relevant Mushroom Body Output Synapses Are Cholinergic

(2016) Oliver Barnstedt et al.   NEURON

Calcium sensor regulation of the CaV2.1 Ca2+channel contributes to long-term potentiation and spatial learning

(2016) Evanthia Nanou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Dopamine Neurons Mediates Reward

(2016) Nobuhiro Yamagata et al.   PLOS BIOLOGY

Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila

(2015) Raphael Cohn et al.   CELL

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation

(2015) L. A. Perkins et al.   GENETICS

Plasticity-driven individualization of olfactory coding in mushroom body output neurons

(2015) Toshihide Hige et al.   NATURE

Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila

(2015) David Owald et al.   NEURON

Heterosynaptic Plasticity Underlies Aversive Olfactory Learning in Drosophila

(2015) Toshihide Hige et al.   NEURON

A single-cross, RNA interference-based genetic tool for examining the long-term maintenance of homeostatic plasticity

(2015) Douglas J. Brusich et al.   Frontiers in Cellular Neuroscience

A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster

(2015) Paula R Haynes et al.   eLife

Reward signal in a recurrent circuit drives appetitive long-term memory formation

(2015) Toshiharu Ichinose et al.   eLife

Muscarinic ACh Receptors Contribute to Aversive Olfactory Learning inDrosophila

(2015) Bryon Silva et al.   NEURAL PLASTICITY

Dopaminergic Modulation of cAMP Drives Nonlinear Plasticity across the Drosophila Mushroom Body Lobes

(2014) Tamara Boto et al.   CURRENT BIOLOGY

Distinct dopamine neurons mediate reward signals for short- and long-term memories

(2014) Nobuhiro Yamagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Octopamine-Mushroom Body Circuit Modulates the Formation of Anesthesia-Resistant Memory in Drosophila

(2013) Chia-Lin Wu et al.   CURRENT BIOLOGY

Presynaptic Inhibition of Gamma Lobe Neurons Is Required for Olfactory Learning in Drosophila

(2013) Shixing Zhang et al.   CURRENT BIOLOGY

Dopaminergic Neurons Encode a Distributed, Asymmetric Representation of Temperature in Drosophila

(2013) S. M. Tomchik   JOURNAL OF NEUROSCIENCE

Two Pairs of Mushroom Body Efferent Neurons Are Required for Appetitive Long-Term Memory Retrieval in Drosophila

(2013) Pierre-Yves Plaçais et al.   Cell Reports

Regulation of CaV2 calcium channels by G protein coupled receptors

(2012) Gerald W. Zamponi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transsynaptic Control of Presynaptic Ca2+ Influx Achieves Homeostatic Potentiation of Neurotransmitter Release

(2012) Martin Müller et al.   CURRENT BIOLOGY

A subset of dopamine neurons signals reward for odour memory in Drosophila

(2012) Chang Liu et al.   NATURE

Compartmentalized calcium dynamics in a C. elegans interneuron encode head movement

(2012) Michael Hendricks et al.   NATURE

Dopamine Is Required for Learning and Forgetting in Drosophila

(2012) Jacob A. Berry et al.   NEURON

Imaging Calcium in Neurons

(2012) Christine Grienberger et al.   NEURON

A GAL4-Driver Line Resource for Drosophila Neurobiology

(2012) Arnim Jenett et al.   Cell Reports

Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila

(2011) Julien Séjourné et al.   NATURE NEUROSCIENCE

Refinement of Tools for Targeted Gene Expression in Drosophila

(2010) B. D. Pfeiffer et al.   GENETICS

The Mushroom Body of AdultDrosophilaCharacterized by GAL4 Drivers

(2009) Yoshinori Aso et al.   JOURNAL OF NEUROGENETICS

Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: anatomical and physiological heterogeneity

(2009) Zhengmei Mao   Frontiers in Neural Circuits

Neuronal assemblies of theDrosophila mushroom body

(2008) Nobuaki K. Tanaka et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Imaging of an Early Memory Trace in the Drosophila Mushroom Body

(2008) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning

(2008) Xu Liu et al.   NATURE NEUROSCIENCE