Molecular Architecture of Contactin-associated Protein-like 2 (CNTNAP2) and Its Interaction with Contactin 2 (CNTN2)

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes

(2015) Ning Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1

(2015) Eva N. Rubio-Marrero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains

(2015) Karen Perez de Arce et al.   NEURON

The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study

(2015) Amos Gdalyahu et al.   PLoS One

Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2knockout neurons

(2015) Olga Varea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis

(2015) Delphine Pinatel et al.   Frontiers in Cellular Neuroscience

3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography

(2015) Xing Zhang et al.   Scientific Reports

No Evidence for Association of Autism with Rare Heterozygous Point Mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins

(2015) John D. Murdoch et al.   PLoS Genetics

Shining a light on CNTNAP2: complex functions to complex disorders

(2013) Pedro Rodenas-Cuadrado et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Electron tomography on γ-aminobutyric acid-ergic synapses reveals a discontinuous postsynaptic network of filaments

(2013) Alexander E. Linsalata et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Defining the Contribution of CNTNAP2 to Autism Susceptibility

(2013) Srirangan Sampath et al.   PLoS One

Neuro-glial interactions at the nodes of Ranvier: implication in health and diseases

(2013) Catherine Faivre-Sarrailh et al.   Frontiers in Cellular Neuroscience

Morvan syndrome: Clinical and serological observations in 29 cases

(2012) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies

(2012) Sarosh R Irani et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation

(2012) G. Falivelli et al.   HUMAN MOLECULAR GENETICS

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies

(2012) Nico Melzer et al.   Journal of Neuroinflammation

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia

(2012) Esther B E Becker et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity

(2012) David A. Buchner et al.   MAMMALIAN GENOME

Neuronal autoantigens—pathogenesis, associated disorders and antibody testing

(2012) Eric Lancaster et al.   Nature Reviews Neurology

IPET and FETR: Experimental Approach for Studying Molecular Structure Dynamics by Cryo-Electron Tomography of a Single-Molecule Structure

(2012) Lei Zhang et al.   PLoS One

Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development

(2012) G. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastructure of Synapses in the Mammalian Brain

(2012) K. M. Harris et al.   Cold Spring Harbor Perspectives in Biology

Expanding the clinical spectrum associated with defects in CNTNAP2 and NRXN1

(2011) Anne Gregor et al.   BMC Medical Genetics

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

(2011) Brian J O'Roak et al.   NATURE GENETICS

A Laminin G-EGF-Laminin G Module in Neurexin IV Is Essential for the Apico-Lateral Localization of Contactin and Organization of Septate Junctions

(2011) Swati Banerjee et al.   PLoS One

The Crystal Structure of the α-Neurexin-1 Extracellular Region Reveals a Hinge Point for Mediating Synaptic Adhesion and Function

(2011) Meghan T. Miller et al.   STRUCTURE

The Structure of Neurexin 1α Reveals Features Promoting a Role as Synaptic Organizer

(2011) Fang Chen et al.   STRUCTURE

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

(2010) Eric Lancaster et al.   ANNALS OF NEUROLOGY

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy

(2010) Lei Zhang et al.   JOURNAL OF LIPID RESEARCH

The Expression of TAG-1 in Glial Cells Is Sufficient for the Formation of the Juxtaparanodal Complex and the Phenotypic Rescue of Tag-1 Homozygous Mutants in the CNS

(2010) M. Savvaki et al.   JOURNAL OF NEUROSCIENCE

Electron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system

(2010) Andrea Nans et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON

Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2

(2010) A. A. Scott-Van Zeeland et al.   Science Translational Medicine

The Macromolecular Architecture of Extracellular Domain of αNRXN1: Domain Organization, Flexibility, and Insights into Trans-Synaptic Disposition

(2010) Davide Comoletti et al.   STRUCTURE

Genome-Wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies

(2010) Heather C. Mefford et al.   PLoS Genetics

CNTNAP2 and NRXN1 Are Mutated in Autosomal-Recessive Pitt-Hopkins-like Mental Retardation and Determine the Level of a Common Synaptic Protein in Drosophila

(2009) Christiane Zweier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

An optimized negative-staining protocol of electron microscopy for apoE4•POPC lipoprotein

(2009) Lei Zhang et al.   JOURNAL OF LIPID RESEARCH

Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

(2008) Maricela Alarcón et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Cytogenetic Analysis and Resequencing of Contactin Associated Protein-Like 2 in Autism Spectrum Disorders

(2008) Betul Bakkaloglu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular domains of myelinated axons in the peripheral nervous system

(2008) James L. Salzer et al.   GLIA