Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling

Bioanalysis of 6-diazo-5-oxo-l-norleucine in plasma and brain by ultra-performance liquid chromatography mass spectrometry

(2015) Jesse Alt et al.   ANALYTICAL BIOCHEMISTRY

CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis

(2014) Matilde Todaro et al.   Cell Stem Cell

Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis

(2014) Theerawut Chanmee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway

(2014) Christina M. Ferrer et al.   MOLECULAR CELL

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

(2013) H. M. Itkonen et al.   CANCER RESEARCH

The Warburg effect version 2.0: Metabolic reprogramming of cancer stem cells

(2013) JAVIER MENENDEZ et al.   CELL CYCLE

Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer

(2013) Faton Agani et al.   CURRENT CANCER DRUG TARGETS

Mass Isotopomer Analysis of Metabolically Labeled Nucleotide Sugars and N- and O-Glycans for Tracing Nucleotide Sugar Metabolisms

(2013) Kazuki Nakajima et al.   MOLECULAR & CELLULAR PROTEOMICS

Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells

(2012) M. Tamada et al.   CANCER RESEARCH

Role of UDP-N-Acetylglucosamine (GlcNAc) andO-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis

(2012) Davide Vigetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma

(2012) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD)

(2012) Karl E. Miletti-González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time-Dependent Stabilization of Hypoxia Inducible Factor-1α by Different Intracellular Sources of Reactive Oxygen Species

(2012) Maura Calvani et al.   PLoS One

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway

(2011) Mayumi Jijiwa et al.   PLoS One

Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

(2010) N. Kobayashi et al.   CANCER RESEARCH

Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC

(2010) Kazuki Nakajima et al.   GLYCOBIOLOGY

Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

(2010) David A. Patten et al.   MOLECULAR BIOLOGY OF THE CELL

Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

(2010) Ann H. Klopp et al.   PLoS One

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

(2009) Masahiro Sugimoto et al.   Metabolomics

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry

(2009) F Morrish et al.   ONCOGENE

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis

(2007) Hiroshi Koyama et al.   AMERICAN JOURNAL OF PATHOLOGY