Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growthin Vivo

Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion

(2015) Kenneth A. Stapleford et al.   JOURNAL OF VIROLOGY

Viral quasispecies

(2015) Raul Andino et al.   VIROLOGY

RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

(2015) Cristina Ferrer-Orta et al.   Viruses-Basel

RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence

(2014) Victoria K. Korboukh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase

(2014) Ibrahim M. Moustafa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases

(2014) Grace Campagnola et al.   JOURNAL OF VIROLOGY

The role of mutational robustness in RNA virus evolution

(2013) Adam S. Lauring et al.   NATURE REVIEWS MICROBIOLOGY

Structures of Coxsackievirus, Rhinovirus, and Poliovirus Polymerase Elongation Complexes Solved by Engineering RNA Mediated Crystal Contacts

(2013) Peng Gong et al.   PLoS One

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development

(2012) Spencer A. Weeks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coxsackievirus B3 mutator strains are attenuated in vivo

(2012) N. F. Gnadig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

(2012) Xiaorong Yang et al.   STRUCTURE

What Is the Role of Motif D in the Nucleotide Incorporation Catalyzed by the RNA-dependent RNA Polymerase from Poliovirus?

(2012) Hujun Shen et al.   PLoS Computational Biology

Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity

(2011) Ibrahim M. Moustafa et al.   JOURNAL OF MOLECULAR BIOLOGY

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

(2011) Stéphanie Beaucourt et al.   Jove-Journal of Visualized Experiments

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ribonucleoside Triphosphates as Substrate of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Human Macrophages

(2010) Edward M. Kennedy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated minimization of steric clashes in protein structures

(2010) Srinivas Ramachandran et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A quantitative stopped-flow fluorescence assay for measuring polymerase elongation rates

(2009) Peng Gong et al.   ANALYTICAL BIOCHEMISTRY

The structural changes of T7 RNA polymerase from transcription initiation to elongation

(2009) Thomas A Steitz   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nucleic acid polymerases use a general acid for nucleotidyl transfer

(2009) Christian Castro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accurate Structural Correlations from Maximum Likelihood Superpositions

(2008) Douglas L. Theobald et al.   PLoS Computational Biology