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A Review on the Synthesis and Applications of α-Alkylidene Succinimides

Journal

ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 11, Issue 4, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.202200041

Keywords

allylic activation; alpha-alkylidene succinimides; cycloaddition; itaconimides; Michael reaction

Funding

  1. Centurion University of Technology and Management, Odisha, India

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This review summarizes the biological activity, synthesis, and use of itaconimides/alpha-alkylidene succinimide in numerous useful transformations under various reacting environments.
The widespread biological activity and manifestation of multiple reactive centers in itaconimides/alpha-alkylidene succinimides have made them as one of the valuable synthetic targets. In this domain, various strategies have been developed to portray the proficiency of these N-bearing heterocycles. The current review summarizes the biological activity, synthesis, and use of itaconimides/alpha-alkylidene succinimide in numerous useful transformations under many reacting environments.

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