A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects

VARS2andTARS2Mutations in Patients with Mitochondrial Encephalomyopathies

(2014) Daria Diodato et al.   HUMAN MUTATION

Identification of Lethal Mutations in Yeast Threonyl-tRNA Synthetase Revealing Critical Residues in Its Human Homolog

(2014) Zhi-Rong Ruan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading

(2014) Xiao-Long Zhou et al.   NUCLEIC ACIDS RESEARCH

Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy

(2014) Ye Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human tRNA synthetase catalytic nulls with diverse functions

(2014) W.-S. Lo et al.   SCIENCE

Transfer RNA: A dancer between charging and mis-charging for protein biosynthesis

(2013) Zhou XiaoLong et al.   Science China-Life Sciences

Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote

(2012) Xiao-Long Zhou et al.   NUCLEIC ACIDS RESEARCH

Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment

(2012) J. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of tRNA amino acid-accepting end in aminoacylation and its quality control

(2011) Xiao-Long Zhou et al.   NUCLEIC ACIDS RESEARCH

Aminoacyl Transfer Rate Dictates Choice of Editing Pathway in Threonyl-tRNA Synthetase

(2010) Anand Minajigi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Aminoacyl-tRNA Synthetase-like Protein in Insecta with an Essential Mitochondrial Function

(2010) Tanit Guitart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-specific differences in the requirements for translation quality control

(2010) N. M. Reynolds et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional expansion of human tRNA synthetases achieved by structural inventions

(2009) Min Guo et al.   FEBS LETTERS

The mitochondrial pool of free amino acids reflects the composition of mitochondrial DNA-encoded proteins: indication of a post- translational quality control for protein synthesis

(2008) Catherine Ross-Inta et al.   BIOSCIENCE REPORTS

The CP2 Domain of Leucyl-tRNA Synthetase Is Crucial for Amino Acid Activation and Post-transfer Editing

(2008) Xiao-Long Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human mitochondrial transfer RNAs: Role of pathogenic mutation in disease

(2007) Fernando Scaglia et al.   MUSCLE & NERVE