The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling

Epidermal growth factor-induced hydrogen peroxide production is mediated by dual oxidase 1

(2016) Gábor Sirokmány et al.   FREE RADICAL BIOLOGY AND MEDICINE

Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses

(2016) Milena Hristova et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Profiling the reactivity of cyclic C-nucleophiles towards electrophilic sulfur in cysteine sulfenic acid

(2016) Vinayak Gupta et al.   Chemical Science

Redox-dependent regulation of epidermal growth factor receptor signaling

(2016) David E. Heppner et al.   Redox Biology

TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism

(2015) Hongqiao Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Reactions of 1,3-Diketones with a Dipeptide Isothiazolidin-3-one: Toward Agents That Covalently Capture Oxidized Protein Tyrosine Phosphatase 1B

(2015) Kasi Viswanatharaju Ruddraraju et al.   JOURNAL OF ORGANIC CHEMISTRY

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

(2015) Arden Perkins et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein Topology Determines Cysteine Oxidation Fate: The Case of Sulfenyl Amide Formation among Protein Families

(2015) Lucas A. Defelipe et al.   PLoS Computational Biology

Tuning of Peroxiredoxin Catalysis for Various Physiological Roles

(2014) Arden Perkins et al.   BIOCHEMISTRY

Strained Cycloalkynes as New Protein Sulfenic Acid Traps

(2014) Thomas H. Poole et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases

(2014) M. A. Lemmon et al.   Cold Spring Harbor Perspectives in Biology

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

(2014) D. A. E. Cross et al.   Cancer Discovery

Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells

(2014) Milena Hristova et al.   Redox Biology

Epithelial Wounds Induce Differential Phosphorylation Changes in Response to Purinergic and EGF Receptor Activation

(2013) Amanuel Kehasse et al.   AMERICAN JOURNAL OF PATHOLOGY

Sulfenic acid chemistry, detection and cellular lifetime

(2013) Vinayak Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Redox regulation of protein kinases

(2013) Thu H. Truong et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release

(2013) William Razzell et al.   CURRENT BIOLOGY

Redox regulation of protein kinases

(2013) Aoife Corcoran et al.   FEBS Journal

ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

(2013) Derek Sham et al.   PLoS One

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

(2013) P. A. Schwartz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Irreversible Inhibitors of c-Src Kinase That Target a Nonconserved Cysteine

(2012) Frank E. Kwarcinski et al.   ACS Chemical Biology

Dual Oxidase–1 Is Required for Airway Epithelial Cell Migration and Bronchiolar Reepithelialization after Injury

(2012) Stefan H. Gorissen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Redox Regulation of Epidermal Growth Factor Receptor Signaling through Cysteine Oxidation

(2012) Thu H. Truong et al.   BIOCHEMISTRY

Selective Targeting of Distinct Active Site Nucleophiles by Irreversible Src-Family Kinase Inhibitors

(2012) Nathan N. Gushwa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantification of Protein Sulfenic Acid Modifications Using Isotope-Coded Dimedone and Iododimedone

(2011) Young Ho Seo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nox enzymes in allergic airway inflammation

(2011) Albert van der Vliet   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration

(2011) Dammanahalli K. Jagadeesha et al.   CARDIOVASCULAR RESEARCH

To C or not to C: Direct and indirect redox regulation of Src protein tyrosine kinase

(2011) Gongqin Sun et al.   CELL CYCLE

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity

(2011) Candice E Paulsen et al.   Nature Chemical Biology

The resurgence of covalent drugs

(2011) Juswinder Singh et al.   NATURE REVIEWS DRUG DISCOVERY

Urothelial cells produce hydrogen peroxide through the activation of Duox1

(2010) Ágnes Donkó et al.   FREE RADICAL BIOLOGY AND MEDICINE

Src redox regulation: Again in the front line

(2010) Elisa Giannoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

EGF receptor activation by GPCRs: An universal pathway reveals different versions

(2010) Claus Liebmann   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

(2010) Anton Soucy-Faulkner et al.   PLoS Pathogens

Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction

(2009) Sachin A. Gupte et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases

(2009) Jamel El-Benna et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Activation of Dual Oxidases Duox1 and Duox2

(2009) Sabrina Rigutto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

(2009) Wenjun Zhou et al.   NATURE

Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation

(2009) D. J. Kemble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

Expanding the functional diversity of proteins through cysteine oxidation

(2008) Khalilah G Reddie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane

(2008) Jamel El-Benna et al.   Seminars in Immunopathology