A Cyclic di-GMP-binding Adaptor Protein Interacts with Histidine Kinase to Regulate Two-component Signaling

The Xanthomonas oryzae pv. oryzae PilZ Domain Proteins Function Differentially in Cyclic di-GMP Binding and Regulation of Virulence and Motility

(2015) Fenghuan Yang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production inPseudomonas aeruginosa

(2015) John C. Whitney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication

(2015) C. Lori et al.   NATURE

BrlR fromPseudomonas aeruginosais a c-di-GMP-responsive transcription factor

(2014) Jacob R. Chambers et al.   MOLECULAR MICROBIOLOGY

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP

(2014) Jacob L W Morgan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Novel Cyclic di-GMP Effectors of the YajQ Protein Family Control Bacterial Virulence

(2014) Shi-qi An et al.   PLoS Pathogens

Cyclic Di-GMP Receptor PlzA Controls Virulence Gene Expression through RpoS in Borrelia burgdorferi

(2013) Ming He et al.   INFECTION AND IMMUNITY

Antimicrobial Tolerance of Pseudomonas aeruginosa Biofilms Is Activated during an Early Developmental Stage and Requires the Two-Component Hybrid SagS

(2013) K. Gupta et al.   JOURNAL OF BACTERIOLOGY

Visualizing the Perturbation of Cellular Cyclic di-GMP Levels in Bacterial Cells

(2013) Chun Loong Ho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybrid sensor kinase PA1611 inPseudomonas aeruginosaregulates transitions between acute and chronic infection through direct interaction with RetS

(2013) Weina Kong et al.   MOLECULAR MICROBIOLOGY

Integration of the Second Messenger c-di-GMP into the Chemotactic Signaling Pathway

(2013) M. H. Russell et al.   mBio

Second Messenger Regulation of Biofilm Formation: Breakthroughs in Understanding c-di-GMP Effector Systems

(2012) Chelsea D. Boyd et al.   Annual Review of Cell and Developmental Biology

Molecular analysis of methanogenic archaea in the forestomach of the alpaca (Vicugna pacos)

(2012) Benoit St-Pierre et al.   BMC MICROBIOLOGY

Sticky Situations: Key Components That Control Bacterial Surface Attachment

(2012) O. E. Petrova et al.   JOURNAL OF BACTERIOLOGY

Structural Insights into the Regulatory Mechanism of the Response Regulator RocR from Pseudomonas aeruginosa in Cyclic Di-GMP Signaling

(2012) Ming Wei Chen et al.   JOURNAL OF BACTERIOLOGY

The MerR-Like Transcriptional Regulator BrlR Contributes to Pseudomonas aeruginosa Biofilm Tolerance

(2012) Julie Liao et al.   JOURNAL OF BACTERIOLOGY

Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation inPseudomonas aeruginosaPAO1

(2012) Zhi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production inPseudomonas aeruginosa

(2012) John C. Whitney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The orphan histidine protein kinase SgmT is a c-di-GMP receptor and regulates composition of the extracellular matrix together with the orphan DNA binding response regulator DigR in Myxococcus xanthus

(2012) Tobias Petters et al.   MOLECULAR MICROBIOLOGY

Retracted: Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility inXanthomonas campestris

(2012) Robert P. Ryan et al.   MOLECULAR MICROBIOLOGY

The response threshold ofSalmonellaPilZ domain proteins is determined by their binding affinities for c-di-GMP

(2012) Ingrid Swanson Pultz et al.   MOLECULAR MICROBIOLOGY

Crystallographic snapshot of cellulose synthesis and membrane translocation

(2012) Jacob L. W. Morgan et al.   NATURE

The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP

(2012) C. Baraquet et al.   NUCLEIC ACIDS RESEARCH

Key two-component regulatory systems that control biofilm formation in Pseudomonas aeruginosa

(2011) Helga Mikkelsen et al.   ENVIRONMENTAL MICROBIOLOGY

Analysis of the Borrelia burgdorferi Cyclic-di-GMP-Binding Protein PlzA Reveals a Role in Motility and Virulence

(2011) Joshua E. Pitzer et al.   INFECTION AND IMMUNITY

2-Heptyl-4-Quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas aeruginosa

(2011) D.-G. Ha et al.   JOURNAL OF BACTERIOLOGY

SagS Contributes to the Motile-Sessile Switch and Acts in Concert with BfiSR To Enable Pseudomonas aeruginosa Biofilm Formation

(2011) O. E. Petrova et al.   JOURNAL OF BACTERIOLOGY

Histidine-containing Phosphotransfer Protein-B (HptB) Regulates Swarming Motility through Partner-switching System inPseudomonas aeruginosaPAO1 Strain

(2011) Manish Bhuwan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Structure of the PilZ Domain Protein PA4608 Complex with Cyclic di-GMP Identifies Charge Clustering as Molecular Readout

(2011) Judith Habazettl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression

(2011) Jonathan J. Wilksch et al.   PLoS Pathogens

Second Messenger-Mediated Adjustment of Bacterial Swimming Velocity

(2010) Alex Boehm et al.   CELL

The Novel Two-Component Regulatory System BfiSR Regulates Biofilm Development by Controlling the Small RNA rsmZ through CafA

(2010) O. E. Petrova et al.   JOURNAL OF BACTERIOLOGY

Binding of Cyclic Diguanylate in the Non-catalytic EAL Domain of FimX Induces a Long-range Conformational Change

(2010) Yaning Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sol–gel immobilization of a thermophilic diguanylate cyclase for enzymatic production of cyclic-di-GMP

(2010) Swathi Pasunooti et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

The c-di-GMP Binding Protein YcgR Controls Flagellar Motor Direction and Speed to Affect Chemotaxis by a “Backstop Brake” Mechanism

(2010) Koushik Paul et al.   MOLECULAR CELL

A post-translational, c-di-GMP-dependent mechanism regulating flagellar motility

(2010) Xin Fang et al.   MOLECULAR MICROBIOLOGY

Regulatory RNAs and the HptB/RetS signalling pathways fine-tune Pseudomonas aeruginosa pathogenesis

(2010) Christophe Bordi et al.   MOLECULAR MICROBIOLOGY

Enzymatic synthesis of c-di-GMP using a thermophilic diguanylate cyclase

(2009) Feng Rao et al.   ANALYTICAL BIOCHEMISTRY

Computer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors

(2009) L. Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Determinants for the Activation and Autoinhibition of the Diguanylate Cyclase Response Regulator WspR

(2009) Nabanita De et al.   JOURNAL OF MOLECULAR BIOLOGY

MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump

(2009) Zhe-Xian Tian et al.   MICROBIAL PATHOGENESIS

Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX

(2009) Marcos V.A.S. Navarro et al.   STRUCTURE

A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development

(2009) Olga E. Petrova et al.   PLoS Pathogens

Connecting Quorum Sensing, c-di-GMP, Pel Polysaccharide, and Biofilm Formation in Pseudomonas aeruginosa through Tyrosine Phosphatase TpbA (PA3885)

(2009) Akihiro Ueda et al.   PLoS Pathogens

Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures inPseudomonas aeruginosabiofilms

(2008) Kim B. Barken et al.   ENVIRONMENTAL MICROBIOLOGY

Characterization of the Histidine-containing Phosphotransfer Protein B-mediated Multistep Phosphorelay System inPseudomonas aeruginosaPAO1

(2008) Jye-Lin Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of FleQ fromPseudomonas aeruginosaas a c-di-GMP-responsive transcription factor

(2008) Jason W. Hickman et al.   MOLECULAR MICROBIOLOGY

The role of PilZ domain proteins in the virulence ofXanthomonas campestrispv.campestris

(2008) YVONNE MCCARTHY et al.   MOLECULAR PLANT PATHOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

(2008) Susanne Häussler et al.   PLoS Pathogens