Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells

Prostaglandin E2 Inhibits p53 in Human Breast Adipose Stromal Cells: A Novel Mechanism for the Regulation of Aromatase in Obesity and Breast Cancer

(2015) X. Wang et al.   CANCER RESEARCH

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosisy as a Target for Cancer Therapy?

(2015)   Oncotarget

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells

(2015) Weibo Luo et al.   Oncotarget

p53 Modulates Hsp90 ATPase Activity and Regulates Aryl Hydrocarbon Receptor Signaling

(2014) A. Kochhar et al.   Cancer Prevention Research

p53 Protein Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression

(2014) Sachiyo Okayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

(2013) William J. Israelsen et al.   CELL

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

(2013) Lei Lv et al.   MOLECULAR CELL

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism

(2013) H.-J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CREB-Regulated Transcription Co-Activator Family Stimulates Promoter II-Driven Aromatase Expression in Preadipocytes

(2013) Nirukshi U. Samarajeewa et al.   Hormones & Cancer

Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort

(2012) Serena Masciari et al.   BREAST CANCER RESEARCH AND TREATMENT

Pioglitazone, a PPAR  Agonist, Suppresses CYP19 Transcription: Evidence for Involvement of 15-Hydroxyprostaglandin Dehydrogenase and BRCA1

(2012) K. Subbaramaiah et al.   Cancer Prevention Research

Endocrine-related cancers and the role of AMPK

(2012) Kristy A. Brown et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Increased Levels of COX-2 and Prostaglandin E 2 Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women

(2012) Kotha Subbaramaiah et al.   Cancer Discovery

The Prostaglandin Transporter Regulates Adipogenesis and Aromatase Transcription

(2011) K. Subbaramaiah et al.   Cancer Prevention Research

Obesity Is Associated with Inflammation and Elevated Aromatase Expression in the Mouse Mammary Gland

(2011) K. Subbaramaiah et al.   Cancer Prevention Research

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase

(2010) Kristy A. Brown et al.   BREAST CANCER RESEARCH AND TREATMENT

Altered-Function p53 Missense Mutations Identified in Breast Cancers Can Have Subtle Effects on Transactivation

(2010) Jennifer J. Jordan et al.   MOLECULAR CANCER RESEARCH

The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression

(2010) S. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subcellular Localization of Cyclic AMP-Responsive Element Binding Protein-Regulated Transcription Coactivator 2 Provides a Link between Obesity and Breast Cancer in Postmenopausal Women

(2009) Kristy A. Brown et al.   CANCER RESEARCH

HDAC6 Modulates Hsp90 Chaperone Activity and Regulates Activation of Aryl Hydrocarbon Receptor Signaling

(2009) Vikram D. Kekatpure et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced expression of aromatase in p53-inactivated mammary epithelial cells

(2008) H. K. Choi et al.   ENDOCRINE-RELATED CANCER