Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

Galactose-amidine derivatives as selective antagonists of galectin-9

(2016) Santanu Mandal et al.   CANADIAN JOURNAL OF CHEMISTRY

Identification of a cytotoxic molecule in heat-modified citrus pectin

(2016) Lionel Leclere et al.   CARBOHYDRATE POLYMERS

Galectin-3 inhibition prevents adipose tissue remodelling in obesity

(2016) E Martínez-Martínez et al.   INTERNATIONAL JOURNAL OF OBESITY

Galectin-3 Inhibition Is Associated with Neuropathic Pain Attenuation after Peripheral Nerve Injury

(2016) Zhicong Ma et al.   PLoS One

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

(2015) Sonja Aits et al.   Autophagy

The effect of the size of fluorescent dextran on its endocytic pathway

(2015) Lei Li et al.   CELL BIOLOGY INTERNATIONAL

Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain

(2015) Michelle C Miller et al.   GLYCOBIOLOGY

Galectin-3 Participates in Cardiovascular Remodeling Associated With ObesityNovelty and Significance

(2015) Ernesto Martínez-Martínez et al.   HYPERTENSION

Heat-Modified Citrus Pectin Induces Apoptosis-Like Cell Death and Autophagy in HepG2 and A549 Cancer Cells

(2015) Lionel Leclere et al.   PLoS One

Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice

(2013) A. C. MacKinnon et al.   GLYCOBIOLOGY

The Inhibitory Effects of a Rhamnogalacturonan Ι (RG-I) Domain from Ginseng Pectin on Galectin-3 and Its Structure-Activity Relationship

(2013) Xiaoge Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterical Hindrance Promotes Selectivity of the Autophagy Cargo Receptor NDP52 for the Danger Receptor Galectin-8 in Antibacterial Autophagy

(2013) S. Li et al.   Science Signaling

Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8

(2013) Byeong-Won Kim et al.   Nature Communications

Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death

(2012) M. C. Clark et al.   BLOOD

Analysis of the neutral polysaccharide fraction of MCP and its inhibitory activity on galectin-3

(2012) Xiaoge Gao et al.   GLYCOCONJUGATE JOURNAL

Galectin-3 expression in response to LPS, immunomodulatory drugs and exogenously added galectin-3 in monocyte-like THP-1 cells

(2012) Sanja Dabelic et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Synergistic and Additive Effects of Modified Citrus Pectin With Two Polybotanical Compounds, in the Suppression of Invasive Behavior of Human Breast and Prostate Cancer Cells

(2012) Jiahua Jiang et al.   INTEGRATIVE CANCER THERAPIES

Ligand Induced Galectin-3 Protein Self-association

(2012) Adriana Lepur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding

(2012) Ruud P. M. Dings et al.   JOURNAL OF MEDICINAL CHEMISTRY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3

(2011) Alison C. MacKinnon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again

(2011) Santiago Di Lella et al.   BIOCHEMISTRY

Galectin-3 – A jack-of-all-trades in cancer

(2011) Anna U. Newlaczyl et al.   CANCER LETTERS

Glycosylation, galectins and cellular signaling

(2011) Cecile Boscher et al.   CURRENT OPINION IN CELL BIOLOGY

Structural features for α-galactomannan binding to galectin-1

(2011) Michelle C Miller et al.   GLYCOBIOLOGY

The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins

(2011) Emma Salomonsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modified Citrus Pectin Reduces Galectin-3 Expression and Disease Severity in Experimental Acute Kidney Injury

(2011) Maria Kolatsi-Joannou et al.   PLoS One

Structural Basis for Distinct Binding Properties of the Human Galectins to Thomsen-Friedenreich Antigen

(2011) Cheng-Feng Bian et al.   PLoS One

Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia

(2011) M. Yamamoto-Sugitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pectin – An emerging new bioactive food polysaccharide

(2011) Ellen G. Maxwell et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Monovalent Interactions of Galectin-1

(2010) Emma Salomonsson et al.   BIOCHEMISTRY

GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death

(2010) M. J. Streetly et al.   BLOOD

A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice

(2010) N. Demotte et al.   CANCER RESEARCH

Trafficking of galectin-3 through endosomal organelles of polarized and non-polarized cells

(2010) Dominik Schneider et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and- Independent Prostate Cancer Cells

(2010) Jun Yan et al.   INTEGRATIVE CANCER THERAPIES

Mutational Tuning of Galectin-3 Specificity and Biological Function

(2010) Emma Salomonsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhamnogalacturonan I domains from ginseng pectin

(2009) Li Yu et al.   CARBOHYDRATE POLYMERS

Using pulse field gradient NMR diffusion measurements to define molecular size distributions in glycan preparations

(2009) Michelle C. Miller et al.   CARBOHYDRATE RESEARCH

The structure, function, and biosynthesis of plant cell wall pectic polysaccharides

(2009) Kerry Hosmer Caffall et al.   CARBOHYDRATE RESEARCH

Galectin-3, a marker for vacuole lysis by invasive pathogens

(2009) Irit Paz et al.   CELLULAR MICROBIOLOGY

The  -galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

(2009) M. C Miller et al.   GLYCOBIOLOGY

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

(2008) Vladislav V. Glinsky et al.   CARBOHYDRATE RESEARCH

Recognition of galactan components of pectin by galectin-3

(2008) A. Patrick Gunning et al.   FASEB JOURNAL

Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1

(2008) Nozomu Nishi et al.   GLYCOBIOLOGY

Ligand Reduces Galectin-1 Sensitivity to Oxidative Inactivation by Enhancing Dimer Formation

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY