The Atypical Inhibitor of NF-κB, IκBζ, Controls Macrophage Interleukin-10 Expression

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

(2015) Qian Zhang et al.   NATURE

IκBζ is a key driver in the development of psoriasis

(2015) Claus Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

(2014) Brian Ruffell et al.   CANCER CELL

Akirin2 is critical for inducing inflammatory genes by bridging I B-  and the SWI/SNF complex

(2014) S. Tartey et al.   EMBO JOURNAL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration

(2014) Naoyuki Makita et al.   INTERNATIONAL IMMUNOLOGY

Atypical IκB proteins – nuclear modulators of NF-κB signaling

(2013) Marc Schuster et al.   Cell Communication and Signaling

Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren’s Syndrome-like Autoimmune Disease

(2013) Atsushi Okuma et al.   IMMUNITY

I B  is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence

(2013) E. Alexander et al.   JOURNAL OF CELL SCIENCE

I B  Is a Transcriptional Key Regulator of CCL2/MCP-1

(2013) D. G. Hildebrand et al.   JOURNAL OF IMMUNOLOGY

It takes two to tango: IκBs, the multifunctional partners of NF-κB

(2012) Michael Hinz et al.   IMMUNOLOGICAL REVIEWS

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

I B  augments IL-12- and IL-18-mediated IFN-  production in human NK cells

(2011) Y. Kannan et al.   BLOOD

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level

(2011) V Graupner et al.   CELL DEATH AND DIFFERENTIATION

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

(2010) Kazuo Okamoto et al.   NATURE

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Class-specific Regulation of Pro-inflammatory Genes by MyD88 Pathways and IκBζ

(2008) Hisako Kayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nuclear IκB Protein IκBζ Specifically Binds NF-κB p50 Homodimers and Forms a Ternary Complex on κB DNA

(2008) Dan V. Trinh et al.   JOURNAL OF MOLECULAR BIOLOGY

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

(2008) Alejandro Villagra et al.   NATURE IMMUNOLOGY