Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase

The Biochemical Basis of Vitamin A3 Production in Arthropod Vision

(2016) Darwin Babino et al.   ACS Chemical Biology

Strigolactones, a Novel Carotenoid-Derived Plant Hormone

(2015) Salim Al-Babili et al.   Annual Review of Plant Biology

Utilization of Dioxygen by Carotenoid Cleavage Oxygenases

(2015) Xuewu Sui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties

(2015) Nikolaos Eleftheriadis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic mechanism of a retinoid isomerase essential for vertebrate vision

(2015) Philip D Kiser et al.   Nature Chemical Biology

Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)

(2014) Xuewu Sui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis

(2014) S. Frusciante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of carotenoid cleavage: From bacteria to mammals

(2013) Xuewu Sui et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

(2013) Rosana Álvarez et al.   CHEMICAL REVIEWS

Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)

(2013) Carlo dela Seña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin A and retinoid signaling: genomic and nongenomic effects

(2013) Ziad Al Tanoury et al.   JOURNAL OF LIPID RESEARCH

PDBsum additions

(2013) Tjaart A. P. de Beer et al.   NUCLEIC ACIDS RESEARCH

Quantitative Measurement of the Solvent Accessibility of Histidine Imidazole Groups in Proteins

(2012) Vennela Mullangi et al.   BIOCHEMISTRY

Identification of the Key Residues Determining the Product Specificity of Isomerohydrolase

(2012) Yusuke Takahashi et al.   BIOCHEMISTRY

Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers

(2012) Daniela Buongiorno et al.   COORDINATION CHEMISTRY REVIEWS

Aromatic Residues in the Substrate Cleft of RPE65 Protein Govern Retinol Isomerization and Modulate Its Progression

(2012) Preethi Chander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dke1—structure, dynamics, and function: a theoretical and experimental study elucidating the role of the binding site shape and the hydrogen-bonding network in catalysis

(2012) Hrvoje Brkić et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A New Generation of Crystallographic Validation Tools for the Protein Data Bank

(2011) Randy J. Read et al.   STRUCTURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Three-His Triad in Dke1: Comparisons to the Classical Facial Triad

(2010) Adrienne R. Diebold et al.   BIOCHEMISTRY

Structural Insights into Maize Viviparous14, a Key Enzyme in the Biosynthesis of the Phytohormone Abscisic Acid

(2010) Simon A.J. Messing et al.   PLANT CELL

Source to sink: regulation of carotenoid biosynthesis in plants

(2010) Christopher I. Cazzonelli et al.   TRENDS IN PLANT SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Negative charge of the glutamic acid 417 residue is crucial for isomerohydrolase activity of RPE65

(2009) Olga Nikolaeva et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse β-carotene 15, 15'-monooxygenase

(2009) Eugenia Poliakov et al.   BMC BIOCHEMISTRY

RPE65, Visual Cycle Retinol Isomerase, Is Not Inherently 11-cis-specific

(2009) T. Michael Redmond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

(2009) P. D. Kiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Bacterial Carotenoid Cleavage Dioxygenase Homologues That Cleave the Interphenyl α,β Double Bond of Stilbene Derivatives via a Monooxygenase Reaction

(2008) Erinn K. Marasco et al.   CHEMBIOCHEM

Reaction Mechanism of Apocarotenoid Oxygenase (ACO): A DFT Study

(2008) Tomasz Borowski et al.   CHEMISTRY-A EUROPEAN JOURNAL

Focus on Molecules: RPE65, the visual cycle retinol isomerase

(2008) T. Michael Redmond   EXPERIMENTAL EYE RESEARCH

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions

(2008) Elena G Kovaleva et al.   Nature Chemical Biology