Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree

Repression of rRNA transcription by PARIS contributes to Parkinson's disease

(2015) Hojin Kang et al.   NEUROBIOLOGY OF DISEASE

A Novel Ribosomopathy Caused by Dysfunction of RPL10 Disrupts Neurodevelopment and Causes X-Linked Microcephaly in Humans

(2014) S. S. Brooks et al.   GENETICS

l-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome

(2014) Baoshan Xu et al.   HUMAN MOLECULAR GENETICS

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

Altered translation of GATA1 in Diamond-Blackfan anemia

(2014) Leif S Ludwig et al.   NATURE MEDICINE

Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells

(2014) I. Kwon et al.   SCIENCE

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

A neuroprotective phase precedes striatal degeneration upon nucleolar stress

(2013) G Kreiner et al.   CELL DEATH AND DIFFERENTIATION

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

(2013) Yun Li et al.   Cell Stem Cell

Expression of Expanded CAG Transcripts Triggers Nucleolar Stress in Huntington's Disease

(2013) Ho Tsoi et al.   CEREBELLUM

Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

(2013) Eva Bentmann et al.   FEBS Journal

CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

(2013) Silvia De Rubeis et al.   NEURON

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

(2013) Adam Lesiak et al.   PLoS One

Conserved Regulators of Nucleolar Size Revealed by Global Phenotypic Analyses

(2013) R. A. Neumuller et al.   Science Signaling

Stimulation of mTORC1 with L-leucine Rescues Defects Associated with Roberts Syndrome

(2013) Baoshan Xu et al.   PLoS Genetics

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

(2012) Hosung Jung et al.   NATURE REVIEWS NEUROSCIENCE

Parkinson's Disease DJ-1 L166P Alters rRNA Biogenesis by Exclusion of TTRAP from the Nucleolus and Sequestration into Cytoplasmic Aggregates via TRAF6

(2012) Sandra Vilotti et al.   PLoS One

Ribosomes take control

(2012) M. Barna   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of mTORC2 by Association with the Ribosome

(2011) Vittoria Zinzalla et al.   CELL

Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease

(2011) J Lee et al.   CELL DEATH AND DIFFERENTIATION

Synapses on demand require dendrites at the ready: How defining stages of dendritic development in vitro could inform studies of behaviorally driven information storage in the brain

(2011) Ginger S. Withers et al.   DEVELOPMENTAL PSYCHOBIOLOGY

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

(2011) Karli K. McDonald et al.   HUMAN MOLECULAR GENETICS

Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide-induced DNA damage

(2011) Maciej Pietrzak et al.   JOURNAL OF NEUROCHEMISTRY

BDNF-Promoted Increases in Proximal Dendrites Occur via CREB-Dependent Transcriptional Regulation of Cypin

(2011) M. Kwon et al.   JOURNAL OF NEUROSCIENCE

Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling

(2011) C. Rieker et al.   JOURNAL OF NEUROSCIENCE

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

(2011) Malaika K. Singleton et al.   NEUROBIOLOGY OF DISEASE

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

RNA Polymerase 1-driven Transcription as a Mediator of BDNF-induced Neurite Outgrowth

(2010) Cynthia Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohesinopathies, gene expression, and chromatin organization

(2010) Tania Bose et al.   JOURNAL OF CELL BIOLOGY

RNG105 Deficiency Impairs the Dendritic Localization of mRNAs for Na+/K+ ATPase Subunit Isoforms and Leads to the Degeneration of Neuronal Networks

(2010) N. Shiina et al.   JOURNAL OF NEUROSCIENCE

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Analysis of proteome dynamics in the mouse brain

(2010) J. C. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

(2010) Thomas Wild et al.   PLOS BIOLOGY

Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome

(2009) Joy Armistead et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size

(2009) Karen N. Leung et al.   HUMAN MOLECULAR GENETICS

A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice

(2009) M. Meyer-Luehmann et al.   JOURNAL OF NEUROSCIENCE

Uncoupling Stress Granule Assembly and Translation Initiation Inhibition

(2009) Sophie Mokas et al.   MOLECULAR BIOLOGY OF THE CELL

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

(2009) Stefano Fumagalli et al.   NATURE CELL BIOLOGY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

The post-transcriptional steps of eukaryotic ribosome biogenesis

(2008) A. K. Henras et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of nucleolar transcription as a trigger for neuronal apoptosis

(2008) Katarzyna Kalita et al.   JOURNAL OF NEUROCHEMISTRY

Activation of an Endogenous Suicide Response after Perturbation of rRNA Synthesis Leads to Neurodegeneration in Mice

(2008) R. Parlato et al.   JOURNAL OF NEUROSCIENCE

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function

(2008) Natalie C Jones et al.   NATURE MEDICINE

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES