Multi-Strategy Assessment of Different Uses of QSAR under REACH Analysis of Alternatives to Advance Information Transparency

Toxicity prediction based on artificial intelligence: A multidisciplinary overview

(2021) Efrén Pérez Santín et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

Toward regulatory acceptance and improving the prediction confidence of in silico approaches: a case study of genotoxicity

(2021) Olga Tcheremenskaia et al.   Expert Opinion on Drug Metabolism & Toxicology

Determination of “fitness-for-purpose” of quantitative structure-activity relationship (QSAR) models to predict (eco-)toxicological endpoints for regulatory use

(2021) Samuel J. Belfield et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Consensus versus Individual QSARs in Classification: Comparison on a Large-Scale Case Study

(2020) Cecile Valsecchi et al.   Journal of Chemical Information and Modeling

QSAR Use in REACH Analyses of Alternatives to Predict Human Health and Environmental Toxicity of Alternative Chemical Substances

(2020) Kazue Chinen et al.   Integrated Environmental Assessment and Management

Machine learning of toxicological big data enables read-across structure activity relationships (RASAR) outperforming animal test reproducibility

(2018) Thomas Luechtefeld et al.   TOXICOLOGICAL SCIENCES

Weight of Evidence for Hazard Identification: A Critical Review of the Literature

(2018) Pierre Martin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A large comparison of integrated SAR/QSAR models of the Ames test for mutagenicity$

(2018) E. Benfenati et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Mode of Action (MOA) Assignment Classifications for Ecotoxicology: An Evaluation of Approaches

(2017) A. Kienzler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Computational approaches to chemical hazard assessment

(2017) Thomas Luechtefeld   ALTEX-Alternatives to Animal Experimentation

Advancing alternatives analysis: The role of predictive toxicology in selecting safer chemical products and processes

(2017) Timothy Malloy et al.   Integrated Environmental Assessment and Management

A weight of evidence framework for environmental assessments: Inferring qualities

(2017) Glenn Suter et al.   Integrated Environmental Assessment and Management

Weight of evidence evaluation and systematic review in EU chemical risk assessment: Foundation is laid but guidance is needed

(2016) Marlene Ågerstrand et al.   ENVIRONMENT INTERNATIONAL

Transparency of chemical risk assessment data under REACH

(2016) Ellen Ingre-Khans et al.   Environmental Science-Processes & Impacts

Comparison between bioconcentration factor (BCF) data provided by industry to the European Chemicals Agency (ECHA) and data derived from QSAR models

(2015) Maria I. Petoumenou et al.   ENVIRONMENTAL RESEARCH

Evaluation and comparison of benchmark QSAR models to predict a relevant REACH endpoint: The bioconcentration factor (BCF)

(2015) Andrea Gissi et al.   ENVIRONMENTAL RESEARCH

Integrated testing strategies (ITS) for safety assessment

(2015) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

How are reproductive toxicity and developmental toxicity addressed in REACH dossiers?

(2014) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

Integrated testing strategies for safety assessments

(2014) Thomas Hartung   ALTEX-Alternatives to Animal Experimentation

A survey of frameworks for best practices in weight-of-evidence analyses

(2013) Lorenz R. Rhomberg et al.   CRITICAL REVIEWS IN TOXICOLOGY

QSAR Modeling: Where Have You Been? Where Are You Going To?

(2013) Artem Cherkasov et al.   JOURNAL OF MEDICINAL CHEMISTRY

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

(2011) Gordon Guyatt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Weight-of-evidence evaluation in environmental assessment: Review of qualitative and quantitative approaches

(2009) Igor Linkov et al.   SCIENCE OF THE TOTAL ENVIRONMENT

QSAR models for reproductive toxicity and endocrine disruption in regulatory use – a preliminary investigation†

(2008) G.E. Jensen et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

The Use of (Q)SAR Methods in the Context of REACH

(2008) Uwe Lahl et al.   TOXICOLOGY MECHANISMS AND METHODS