Article
Chemistry, Multidisciplinary
Praseetha R. Nair, S. Sreeja, G. S. Sailaja
Summary: This study developed a biodegradable scaffold using a Cissus quadrangularis hexane extract integrated with porous chitosan-collagen, demonstrating excellent microarchitecture, biomineralization ability, and mechanical stability, making it a promising candidate for regenerative bone tissue engineering.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Polymer Science
Junchao Huang, Yi Zhong, Xi Zhang, Huan Xu, Caizhen Zhu, Jie Cai
Summary: This research presents a pilot-scale wet-spinning method that overcomes the main obstacles in producing chitin multifilament, preparing a stable chitin spinning dope through dissolution and aging in a KOH/urea solution, and wet-spinning to obtain multifilament, ultimately resulting in chitosan multifilaments with excellent mechanical properties and cytocompatibilities.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Polymer Science
Irina Kuznik, Iris Kruppke, Chokri Cherif
Summary: Ionic liquids offer alternative methods for the processing of natural biopolymers like chitosan. In this study, 1-butyl-3-methylimidazolium acetate (BmimOAc) was used as a solvent to manufacture pure chitosan-based monofilaments through a wet spinning process. The study provides valuable knowledge for the development of wet spinning process and manufacturing of pure chitosan fibers.
Article
Polymer Science
Ghasem Mohammadkhani, Sunil Kumar Ramamoorthy, Karin H. Adolfsson, Amir Mahboubi, Minna Hakkarainen, Akram Zamani
Summary: Adipic acid was evaluated as a novel solvent for wet spinning of chitosan fibers, showing improved properties compared to conventional solvents. The use of adipic acid as a solvent resulted in higher mechanical strength of chitosan fibers.
Article
Materials Science, Paper & Wood
Qian Gao, Jiabao Wang, Jing Liu, Yuda Wang, Jinge Guo, Ziyi Zhong, Xinliang Liu
Summary: Cellulose nanocrystals with high crystallinity exhibit high mechanical stiffness and strength, but their dispersibility limits spinnability and orientation. By oxidizing nanocellulose to obtain regionally oxidized CNCs with carboxyl groups, and using chitosan as a sheath solution to induce orientation, oriented reinforced composite filaments can achieve a high mechanical strength of 104 MPa with an orientation index of 0.73. The tensile strength and elastic modulus of these filaments increased significantly compared to unmodified CNCs spun fibers.
Article
Engineering, Environmental
Cheng Chen, Xiaoyu Jia, Xiaorui Li, Mingyang Shi, Jiayi Hu, Mengyao Song, Shuwang Wu, Hongliang Dai, Xingang Wang, Hongya Geng
Summary: In this study, spectrally selective fabrics for all-day low-temperature cooling were developed using a simple wet-spinning technique. The fabrics exhibited high reflectivity in the solar window and high infrared emissivity within the atmospheric transparency window, making them suitable for effective radiative cooling. Additionally, the fabrics showed great cloth comfort due to their physical properties.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Guoxing Hu, Fan Luo, Jie Han, Jixiang Li, Changrui Zhou, Cheng Yang, Ziteng Wang, Wenge Yang, Yonghong Hu
Summary: In this study, EGCG/HP-8-CD inclusion complexes were prepared by ultrasound-mediated synthesis. EGCG/HP-8-CD and PCL/CSO nanofiber films were rapidly prepared for fruit preservation packaging. The prepared membranes showed enhanced water vapor permeability, decreased crystallinity, increased hydrophilicity, improved thermal stability, long lasting release of EGCG, and good antibacterial activity in vitro and vivo. These findings suggest that ELS is promising for the development of postharvest antifungal nanofiber membranes.
FOOD HYDROCOLLOIDS
(2023)
Article
Polymer Science
Javier Jimenez, Ericka Ford
Summary: The use of Hansen Solubility Parameters and radial energy distribution to quantitatively differentiate wet spinning from gel spinning by comparing the affinity between the coagulation bath and the polymer. This method has broad applicability to various polymeric materials in fiber, film, and membrane technologies.
Article
Engineering, Biomedical
Xiaolian Niu, Miao Qin, Mengjie Xu, Liqin Zhao, Yan Wei, Yinchun Hu, Xiaojie Lian, Song Chen, Weiyi Chen, Di Huang
Summary: The study involved the fabrication of electrospun PA6/CS scaffolds using electrospinning technology, followed by mineralization in 1.5x simulated body fluid to grow hydroxyapatite layer on the surface. The resulting scaffolds exhibited excellent biocompatibility, mechanical properties, and mimicry of natural ECM structure. The research findings highlight the potential of these mineralized PA6/CS composite scaffolds for bone tissue engineering applications.
BIOMEDICAL MATERIALS
(2021)
Article
Engineering, Environmental
Kezhong Wang, Yunfeng Chao, Zhiqi Chen, Sepidar Sayyar, Caiyun Wang, Gordon Wallace
Summary: A facile coaxial wet-spinning method was used to continuously produce hollow graphene fibers with high conductivity and flexibility. The resulting fibers exhibited outstanding electrochemical and mechanical properties, making them promising candidates for use in wearable supercapacitors and electronics.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Reza Khalili, Mehrorang Ghaedi, Mohammad Parvinnia, Mohammad Mehdi Sabzehmeidani
Summary: In this study, Mn-Fe LDH/CS composite was successfully prepared and used for the simultaneous removal of IC and SY dyes. The first order derivative spectrophotometric method was applied to measure IC and SY simultaneously, and the pseudo second order model was found to be the best fitting model under the optimum conditions. The adsorption isotherm of dyes followed the Langmuir isotherm model.
SURFACES AND INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Zhongcheng Li, Yuhao Zeng, Qian Ren, Longjiang Ding, Sili Han, Die Hu, Ziqian Lu, Luoyao Wang, Yinmo Zhang, Linglin Zhang
Summary: Biomimetic mineralization aims to reverse dental caries through bio-inspired strategies, focusing on both mineralization promotion and collagen protection. This study evaluated the effects of carboxymethyl chitosan (CMC) as a glycosaminoglycan analog for biomimetic modification of collagen. CMC successfully improved the hydrophilicity, calcium absorption capacity, and thermal degradation resistance of collagen. It also inhibited the activity of endogenous matrix metalloproteinases in demineralized dentin. CMC biomodification enhanced cross-linking and intrafibrillar mineralization of collagen, especially in the two-dimensional monolayer reconstituted collagen model. This study provided a comprehensive biomimetic mineralization strategy with collagen protection and expanded the application of chitosan-based materials in dentistry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Paper & Wood
Hao Shen, Tingyu Sun, Hao Wu, Lujie Wang, Haodong Zhang, Jinping Zhou
Summary: This study developed a new method to prepare high wet strength fibers and characterized their properties. The results showed that these fibers had excellent mechanical properties in the wet state and also exhibited dielectric behavior, suggesting potential applications in electronic components and textiles.
Article
Chemistry, Applied
Swarup Roy, Jong-Whan Rhim
Summary: Quercetin-loaded chitosan nanoparticles (QCNP) were prepared using a simple one-pot chemical reaction and incorporated into chitosan-based bioactive packaging films with excellent UV blocking properties. The addition of QCNP influenced the physical properties of the films and enhanced the release of quercetin under acidic and alcoholic conditions, showing potent antioxidant and antibacterial activity. The developed chitosan/QCNP-based films have promising applications in active food packaging.
FOOD HYDROCOLLOIDS
(2021)
Article
Polymer Science
Khoa Dang Nguyen
Summary: Chitin fibers were successfully prepared by phase inversion at different temperatures, leading to denser structures and improved mechanical properties as the concentration and temperature of the chitin solution increased. The green synthesis route showed high potential for the fabrication of chitin fibers with enhanced properties for biomedical applications.
Article
Materials Science, Multidisciplinary
Menekse Ermis
Summary: This study synthesized a soft photo-crosslinked gelatin methacrylate hydrogel with long in vitro lifetime, and formed stem cells and endothelial cells into spheroids to induce prevascular network formation. Spheroids showed higher cell viability and better gel mechanical properties compared to the same combination of cells.
JOURNAL OF MATERIALS RESEARCH
(2021)
Article
Materials Science, Multidisciplinary
Semih Calamak, Menekse Ermis
Summary: The in situ synthesis of AgNPs on 3D-printed PLA scaffolds using UV irradiation can significantly enhance the surface hydrophilicity of the scaffolds, making it useful for various biomedical applications such as cell culture, biosensors, and wound healing.
JOURNAL OF MATERIALS RESEARCH
(2021)
Review
Engineering, Biomedical
Dilara Goksu Tamay, Nesrin Hasirci
Summary: This review provides a brief overview of the chemical structures and properties of bioink materials, and their applications in producing 3D tissue constructs.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2021)
Correction
Materials Science, Multidisciplinary
Semih Calamak, Menekse Ermis
Summary: The article has been updated to change the graphical abstract.
JOURNAL OF MATERIALS RESEARCH
(2021)
Article
Metallurgy & Metallurgical Engineering
Ina Beate Jenssen, Seniz Ucar, Ole Morten Dotterud, Oluf Bockman, Jens-Petter Andreassen
Summary: The study found that increasing reaction temperature and residence time can improve the filtration performance in iron removal process in the nickel industry, reducing specific filter cake resistance and moisture content, and achieving particles with higher crystallinity and stability towards aggregation. These improvements were attributed to the significant decrease in supersaturation at steady state at higher temperatures.
Article
Engineering, Biomedical
Senem Buyuksungur, Vasif Hasirci, Nesrin Hasirci
Summary: The study fabricates 3D printed hybrid scaffolds using PCL and GelMA carrying DPSCs, combining osteoinductivity support from GelMA and mechanical strength from PCL for bone tissue engineering applications. The hybrid scaffolds showed high stability and compressive moduli similar to trabecular bone. DPSCs exhibited high viability and osteogenic differentiation within GelMA, indicating great potential for bone tissue engineering applications.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Nanoscience & Nanotechnology
Dilara Goksu Tamay, Seyda Gokyer, Jurgen Schmidt, Alina Vladescu, Pinar Yilgor Huri, Vasif Hasirci, Nesrin Hasirci
Summary: The study focused on modifying magnesium-calcium alloys with calcium phosphate or doped with zinc and gallium to enhance their biocompatibility and corrosion resistance. The modified alloys showed decreased corrosivity and increased cell affinity, making them novel candidates for biodegradable metallic implants in orthopedic applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Chemistry, Multidisciplinary
Yangzhi Zhu, Shaopei Li, Jinghang Li, Natashya Falcone, Qingyu Cui, Shilp Shah, Martin C. Hartel, Ning Yu, Patric Young, Natan Roberto Barros, Zhuohong Wu, Reihaneh Haghniaz, Menekse Ermis, Canran Wang, Heemin Kang, Junmin Lee, Solmaz Karamikamkar, Samad Ahadian, Vadim Jucaud, Mehmet R. Dokmeci, Han-Jun Kim, Ali Khademhosseini
Summary: Smart contact lenses (SCLs) are wearable intelligent ocular prosthetic devices capable of monitoring various physiological parameters and delivering drugs for the treatment of ocular diseases. This comprehensive review discusses the current status, potential, and future opportunities of SCL development, covering fabrication, applications, and commercialization.
ADVANCED MATERIALS
(2022)
Article
Multidisciplinary Sciences
Ozkan Cesur, Tugba Endogan Tanir, Pinar Celepli, Fatma Ozarslan, Sema Hucumenoglu, Adnan Karaibrahimoglu, Nesrin Hasirci
Summary: The study aimed to prepare a bioactive and biodegradable bilayer mesh using FGF-loaded gelatin and PCL films for esophageal anastomosis treatment. Results showed that the FGF-loaded mesh improved tissue healing and repair of the esophageal defects.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Menekse Ermis, Ezgi Antmen, Ozgur Kuren, Utkan Demirci, Vasif Hasirci
Summary: Microfabrication technologies have been widely used in cell biology and cancer research. In this study, a transparent cell culture chip was developed to monitor the behavior of breast cancer cells. The chip proved to be advantageous in analyzing live cells and studying breast cancer cell-substrate interactions.
Article
Crystallography
Ina Beate Jenssen, Oluf Bockman, Jens-Petter Andreassen, Seniz Ucar
Summary: This study investigated the effects of temperature, seeding, and magnesium presence on the formation of various solid phases in the crystallization of nickel sulfate from an industrial perspective. Results showed that magnesium promoted the formation of NiSO4 center dot 7H(2)O in solution and increased its stability, while inhibiting the phase transformation towards alpha-NiSO4 center dot 6H(2)O. Understanding the different solid phases and their stability can help in decision-making for the best suited solid product type.
Article
Engineering, Chemical
Andreas Bogen Kristiansen, Nathan Church, Seniz Ucar
Summary: Intense research has been conducted on magnetite nanoparticles and their synthesis methods due to their unique magnetic properties, which make them ideal candidates for various technological applications. By controlling particle characteristics such as size, shape, and crystallinity, the magnetic properties of magnetite can be strictly regulated for optimal use. Bioinspired pathways and the use of regulatory additives provide versatile synthesis platforms for tailored magnetite nanoparticles.
Article
Materials Science, Biomaterials
Ezgi Antmen, Menekse Ermis, Ozgur Kuren, Kemal Beksac, Cigdem Irkkan, Vasif Hasirci
Summary: In this study, the combination of conventional molecular-level evaluations and in vitro methods on micropatterned biomaterial surfaces was used to assess breast adenocarcinoma patients. The results showed that molecular markers and shape descriptors could distinguish cells from different locations and patients. Cells with the highest metastatic and invasive properties exhibited both the highest deformability and the highest level of metastatic markers. By combining molecular markers with nuclear deformation, the detection and separation of subpopulations in heterogeneous breast cancer specimens at the single-cell level can be improved.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Energy & Fuels
Silje Bordvik, Seniz Ucar, Titus S. van Erp, Erling Naess
Summary: This study presents a model for quantifying silica deposition from superheated depressurized steam. The results provide important insights into the mechanisms governing precipitation from deep geothermal wells. The predicted deposition rate and amount can be used to improve industrial designs and decrease energy costs.
Article
Engineering, Biomedical
Menekse Ermis, Natashya Falcone, Natan Roberto De Barros, Marvin Mecwan, Reihaneh Haghniaz, Auveen Choroomi, Mahsa Monirizad, Yeji Lee, Jihyeon Song, Hyun-Jong Cho, Yangzhi Zhu, Heemin Kang, Mehmet R. Dokmeci, Ali Khademhosseini, Junmin Lee, Han -Jun Kim
Summary: The tumor microenvironment, particularly the matrix component, plays a crucial role in the progression and therapeutic responsiveness of PDAC. By engineering hyaluronic acid and gelatin-based hydrogels to mimic desmoplastic matrices, a multicellular pancreatic tumor model is developed that allows for a better understanding and monitoring of PDAC progression, with potential applications in personalized medicine and drug testing.
BIOACTIVE MATERIALS
(2023)