An overview of the current state of phage therapy for the treatment of biofilm-related infections

Bacteriophage therapy for infections in CF

(2021) Benjamin K. Chan et al.   PEDIATRIC PULMONOLOGY

Overcoming Challenges to Make Bacteriophage Therapy Standard Clinical Treatment Practice for Cystic Fibrosis

(2021) Renee N. Ng et al.   Frontiers in Microbiology

Phage–Bacteria Interactions in Potential Applications of Bacteriophage vB_EfaS-271 against Enterococcus faecalis

(2021) Gracja Topka-Bielecka et al.   Viruses-Basel

Comparison of Enterococcus faecalis Biofilm Removal Efficiency among Bacteriophage PBEF129, Its Endolysin, and Cefotaxime

(2021) Hyun Keun Oh et al.   Viruses-Basel

Clinical Experience of Personalized Phage Therapy Against Carbapenem-Resistant Acinetobacter baumannii Lung Infection in a Patient With Chronic Obstructive Pulmonary Disease

(2021) Xin Tan et al.   Frontiers in Cellular and Infection Microbiology

Aminoglycosides Antagonize Bacteriophage Proliferation, Attenuating Phage Suppression of Bacterial Growth, Biofilm Formation, and Antibiotic Resistance

(2021) Pengxiao Zuo et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Potent antibody-mediated neutralization limits bacteriophage treatment of a pulmonary Mycobacterium abscessus infection

(2021) Rebekah M. Dedrick et al.   NATURE MEDICINE

Coevolutionary phage training leads to greater bacterial suppression and delays the evolution of phage resistance

(2021) Joshua M. Borin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phage Therapy Experience at the Eliava Phage Therapy Center: Three Cases of Bacterial Persistence

(2021) Elisabed Zaldastanishvili et al.   Viruses-Basel

Understanding the Complex Phage-Host Interactions in Biofilm Communities

(2021) Diana P. Pires et al.   Annual Review of Virology

Isolation and application of bacteriophages alone or in combination with nisin against planktonic and biofilm cells of Staphylococcus aureus

(2020) Hoang Minh Duc et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Using Bacteriophages as a Trojan Horse to the Killing of Dual-Species Biofilm Formed by Pseudomonas aeruginosa and Methicillin Resistant Staphylococcus aureus

(2020) Tamta Tkhilaishvili et al.   Frontiers in Microbiology

Combining bacteriophages with cefiderocol and meropenem/vaborbactam to treat a pan‐drug resistant Achromobacter species infection in a pediatric cystic fibrosis patient

(2020) Andrew B. Gainey et al.   PEDIATRIC PULMONOLOGY

Phage-Antibiotic Synergy Is Driven by a Unique Combination of Antibacterial Mechanism of Action and Stoichiometry

(2020) Carmen Gu Liu et al.   mBio

The Potential Innovative Use of Bacteriophages Within the DAC® Hydrogel to Treat Patients With Knee Megaprosthesis Infection Requiring “Debridement Antibiotics and Implant Retention” and Soft Tissue Coverage as Salvage Therapy

(2020) Tristan Ferry et al.   Frontiers in Medicine

A Review of Topical Phage Therapy for Chronically Infected Wounds and Preparations for a Randomized Adaptive Clinical Trial Evaluating Topical Phage Therapy in Chronically Infected Diabetic Foot Ulcers

(2020) Christopher Anthony Duplessis et al.   Antibiotics-Basel

Salvage Bacteriophage Therapy for a Chronic MRSA Prosthetic Joint Infection

(2020) James B. Doub et al.   Antibiotics-Basel

Bacteriophage-antibiotic combinations against ciprofloxacin/ceftriaxone-resistant Escherichia coli in vitro and in an experimental Galleria mellonella model

(2020) Lei Wang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The Protective Effect of Staphylococcus epidermidis Biofilm Matrix against Phage Predation

(2020) Luís D. R. Melo et al.   Viruses-Basel

Biofilms in Diabetic Foot Ulcers: Significance and Clinical Relevance

(2020) Cassandra Pouget et al.   Microorganisms

Aminoglycoside Antibiotics Inhibit Mycobacteriophage Infection

(2020) Zheng Jiang et al.   Antibiotics-Basel

Phage Therapy as Adjuvant to Conservative Surgery and Antibiotics to Salvage Patients With Relapsing S. aureus Prosthetic Knee Infection

(2020) Tristan Ferry et al.   Frontiers in Medicine

Novel bacteriophage therapy for treatment of left ventricular assist device infection

(2019) Saima Aslam et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Adjunct phage treatment enhances the effectiveness of low antibiotic concentration against Staphylococcus aureus biofilms in vitro

(2019) James Dickey et al.   PLoS One

Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination

(2019) Ran Nir-Paz et al.   CLINICAL INFECTIOUS DISEASES

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

(2019) Kaitlyn E. Kortright et al.   Cell Host & Microbe

Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci

(2019) Anushila Chatterjee et al.   INFECTION AND IMMUNITY

Big Impact of the Tiny: Bacteriophage–Bacteria Interactions in Biofilms

(2019) Mads Frederik Hansen et al.   TRENDS IN MICROBIOLOGY

Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae

(2019) Ruopeng Cai et al.   Frontiers in Microbiology

Early clinical experience of bacteriophage therapy in 3 lung transplant recipients

(2019) Saima Aslam et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Efficacy and safety assessment of two enterococci phages in an in vitro biofilm wound model

(2019) Luís D. R. Melo et al.   Scientific Reports

The Removal of Endo- and Enterotoxins From Bacteriophage Preparations

(2019) Ville Hietala et al.   Frontiers in Microbiology

Bacteriophage Application for Difficult-to-treat Musculoskeletal Infections: Development of a Standardized Multidisciplinary Treatment Protocol

(2019) Onsea et al.   Viruses-Basel

Pseudomonas aeruginosa PA5oct Jumbo Phage Impacts Planktonic and Biofilm Population and Reduces Its Host Virulence

(2019) Tomasz Olszak et al.   Viruses-Basel

Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion

(2019) Eric T. Sumrall et al.   PLoS Pathogens

Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections

(2018) Nicholas M. Maurice et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Stability of bacteriophages in burn wound care products

(2017) Maia Merabishvili et al.   PLoS One

A Genotypic Analysis of Five P. aeruginosa Strains after Biofilm Infection by Phages Targeting Different Cell Surface Receptors

(2017) Diana P. Pires et al.   Frontiers in Microbiology

Critical review on biofilm methods

(2016) Joana Azeredo et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics

(2014) D. Lebeaux et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Method for Generation Phage Cocktail with Great Therapeutic Potential

(2012) Jingmin Gu et al.   PLoS One