Review
Ophthalmology
Alan Yee, Karen Walsh, Marc Schulze, Lyndon Jones
Summary: Reusable soft contact lenses continue to be popular among wearers, but the additional steps required for cleaning and disinfecting may lead to non-compliant behavior and potentially impact wearers' health. Educating patients, regulating the use of contact lens care solutions, and reevaluating global standards are key strategies to better support contact lens wearers.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Marta Vianya-Estopa, Nery Garcia-Porta, David P. Pinero, Luisa Simo Mannion, Eldre W. Beukes, James S. Wolffsohn, Peter M. Allen
Summary: The study found that most contact lens wearers in Spain followed hand hygiene regulations during the COVID-19 pandemic, but there were still areas for improvement such as the 20-second handwashing rule and using shared towels. Factors needing attention included lens case cleaning and renewal, avoiding water exposure, and knowing when to cease lens wear. Continued education by eye care practitioners is essential to ensure safe contact lens wear during the pandemic.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Mechanics
I Sevostianov, M. Kachanov
Summary: This study examines the incremental normal compliance of an irregular contact between two elastic half spaces, modeling the contact as an external crack. By utilizing an approximate expression for stress intensity factor and Rice's theorem, the crack compliance is evaluated. The results are applicable to a wide range of contact shapes and include the formulation of bounds similar to Hill's comparison theorem. Additionally, the study explores the relationship between elasticity and conductivity in contact conductance.
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS
(2021)
Article
Ophthalmology
Marta Vianya-Estopa, James S. Wolffsohn, Eldre Beukes, Mike Trott, Lee Smith, Peter M. Allen
Summary: During the COVID-19 pandemic, majority of contact lens wearers followed hygiene recommendations, but some reduced the frequency of lens usage. High compliance was observed in handwashing practices, however, soft reusable lens wearers exhibited lower compliance in lens wear and care compared to daily disposable lens wearers.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Business
Hong Qiu, Samia Chreim, Mark Freel
Summary: This paper uses a tension lens to examine how academic and non-academic staff in university settings manage tensions associated with entrepreneurship-related activities. By drawing on three theoretical perspectives, the study analyzes the reward tension and the resource tension experienced by individuals in two Canadian universities. The findings suggest that strategies for managing these tensions influence the type and scale of entrepreneurship-related activities.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2023)
Article
Ophthalmology
Ananya Datta, Mark D. P. Willcox, Fiona Stapleton
Summary: This study examined the rate and level of microbial contamination of silver and non-silver barrel contact lens storage cases in vivo, finding that the use of silver cases does not reduce the overall rate and level of bacterial contamination, but can result in higher numbers of bacteria isolated from the cases when used in combination with hydrogel lenses.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
G. Lynn Mitchell, Kathryn Richdale, Dawn Lam, Heidi Wagner, Beth T. Kinoshita, Aaron B. Zimmerman, Luigina Sorbara, Bernard Rosner
Summary: The development and validation of the Contact Lens Risk Survey (CLRS) showed excellent psychometric properties in identifying patients at risk for soft contact lens-related complications. The tool demonstrated good repeatability, consistency, and discriminative ability in distinguishing between individuals with and without red eye events related to contact lens wear.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Chemistry, Multidisciplinary
Hayoung Song, Haein Shin, Hunkyu Seo, Wonjung Park, Byung Jun Joo, Jeongho Kim, Jeonghyun Kim, Hong Kyun Kim, Jayoung Kim, Jang-Ung Park
Summary: Researchers have developed a wireless and soft smart contact lens that can quantitatively record cholesterol levels in tear fluids in real-time for monitoring patients with hyperlipidemia. This lens incorporates an electrochemical biosensor, stretchable antenna, and integrated circuits for wireless communication, allowing it to be operated remotely using a smartphone without obstructing the wearer's vision. Animal models and human tests have demonstrated the feasibility of this smart contact lens for diagnosing cholesterol-related diseases, as well as its good biocompatibility, wearability, and reliability as a non-invasive healthcare device.
Article
Chemistry, Multidisciplinary
Yangzhi Zhu, Rohollah Nasiri, Elham Davoodi, Shiming Zhang, Sourav Saha, Matthew Linn, Lu Jiang, Reihaneh Haghniaz, Martin C. Hartel, Vadim Jucaud, Mehmet R. Dokmeci, Anna Herland, Ehsan Toyserkani, Ali Khademhosseini
Summary: The study investigates the use of contact lenses with microchannels to enhance tear flow from the pre-lens tear film to the post-lens ocular surface. The results demonstrate that the tear transport can be enhanced by an artificial eyelid motion in a pressure range similar to human eyelid pressure. This research shows the feasibility of developing microfluidic contact lenses to prevent or minimize contact lens-induced dry eye and discomfort.
Article
Medicine, General & Internal
Yu Xue, Jiaqi Zhou, Zhi Chen, Feng Xue, Li Zeng, Xiaomei Qu, Xingtao Zhou
Summary: This study aims to investigate the factors affecting long-term compliance with rigid gas-permeable contact lens wear in patients with keratoconus (KC). The results showed that subjective experiences, such as visual acuity, overall satisfaction, and quality of life, significantly influence long-term compliance with RGPCL wear, while ocular biometrics do not have a significant effect.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Emmanuel Kobia-Acquah, Prince Kwaku Akowuah, Ellen Konadu Antwi-Adjei, Philip Mensah Forkuo, Nana Yaa Koomson, Samuel Odoi Odotei, Emmanuel Alabi, Richard Donkor
Summary: In Ghana, the prevalence of contact lens complications is relatively high, with soft contact lens wearers being more susceptible. The most common complication reported is giant papillary conjunctivitis. Inappropriate lens cleaning and poor personal hygiene are the main causes of complications.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Genis Cardona, Silvia Alonso, Anna Busquets
Summary: During a 3-month COVID-19 lockdown in Spain, contact lens compliance was poor, particularly in terms of handwashing and storage case hygiene, highlighting the importance of enhancing patient-practitioner communication to reduce the risk of ocular transmission and virus tropism.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Anna A. Tichenor, Stacey S. Cofield, Drew Gann, Marian Elder, Alison Ng, Karen Walsh, Lyndon W. Jones, Jason J. Nichols
Summary: A retrospective study comparing the frequency of contact lens complications between hydrogen peroxide and multipurpose solution users found no significant differences, but showed that multipurpose solution users were more likely to report discomfort.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Article
Ophthalmology
Manbir Nagra, Neil Retallic, Shehzad A. Naroo
Summary: During the COVID-19 pandemic, most soft contact lens wearers either maintained or increased their wearing time. The main reasons for decreased lens wear were less frequent outings and concerns about hygiene. The majority of respondents expressed a desire to return to their pre-pandemic lens wear times once the pandemic is over.
CONTACT LENS & ANTERIOR EYE
(2022)
Article
Ophthalmology
Chandra V. Mickles, Beth T. Kinoshita, Dawn Lam, Heidi Wagner, Aaron B. Zimmerman, Luigina Sorbara, G. Lynn Mitchell, Bernard Rosner, Kathryn Richdale
Summary: The study tested the Contact Lens Assessment in Youth Contact Lens Risk Survey (CLRS) scoring algorithm in soft contact lens wearers and found significant differences between individuals presenting with soft contact lens-related adverse events and healthy controls, supporting the identification of high-risk patients and targeted interventions.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Diego Garcia-Ayuso, Johnny Di Pierdomenico, Esmeralda Moya-Rodriguez, Francisco J. Valiente-Soriano, Caridad Galindo-Romero, Paloma Sobrado-Calvo
Summary: The study found that female gender, online class attendance, longer hours spent in online classes, and contact lens wearers were more likely to experience dry eye symptoms. This suggests that the synchronous hybrid learning environment may increase students' exposure to video display terminals and the prevalence of dry eye symptoms.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2022)
Article
Biochemistry & Molecular Biology
Marina Martinez-Carmona, Fernando Lucas-Ruiz, Alejandro Gallego-Ortega, Caridad Galindo-Romero, Maria Norte-Munoz, Maria Jose Gonzalez-Riquelme, Francisco J. Valiente-Soriano, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Summary: Ly6c can serve as a specific marker of mouse vasculature, particularly of the retinal vascular plexuses. In injured retinas, Ly6c expression increases, correlating with vascular formation and classical monocyte/macrophage activation. This study provides a new tool for qualitative and quantitative assessment of vascular changes in health and disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Ophthalmology
Johnny Di Pierdomenico, Alejandro Gallego-Ortega, Ana Martinez-Vacas, David Garcia-Bernal, Manuel Vidal-Sanz, Maria P. Villegas-Perez, Diego Garcia-Ayuso
Summary: Syngeneic bone marrow mononuclear stem cell transplantation can reduce photoreceptor degeneration and have anti-gliotic effects on Muller cells, but does not improve retinal function.
ACTA OPHTHALMOLOGICA
(2022)
Article
Chemistry, Multidisciplinary
Raquel Boia, Paul A. N. Dias, Caridad Galindo-Romero, Hugo D. Ferreira, Ines D. Aires, Manuel Vidal-Sanz, Marta Agudo-Barriuso, Rui Bernardes, Paulo F. Santos, Herminio C. de Sousa, Antonio Francisco Ambrosio, Mara E. M. Braga, Ana Raquel Santiago
Summary: The use of PCL implants loaded with selective A3R agonists has shown to effectively protect RGCs and improve their function, although it does not prevent retinal thinning due to transient ischemia.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Ophthalmology
Emma Cabanes-Marti, Diego Garcia-Ayuso
Summary: During the COVID-19 pandemic, children wearing dual-focus soft contact lenses for myopia control showed smaller increases in spherical equivalent refraction and axial length compared to myopic children wearing spectacles. Both groups had restricted outdoor activities during the lockdown, with an increase in outdoor time after the lockdown only observed in the spectacle group.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Review
Anatomy & Morphology
Caridad Galindo-Romero, Maria Norte-Munoz, Alejandro Gallego-Ortega, Kristy T. Rodriguez-Ramirez, Fernando Lucas-Ruiz, Maria Josefa Gonzalez-Riquelme, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Summary: This article summarizes the main topographical and functional characteristics of the rat retina, focusing on retinal ganglion cells and photoreceptors. Understanding the normal state of these neurons is crucial for studying neuronal survival and protection.
FRONTIERS IN NEUROANATOMY
(2022)
Article
Biochemistry & Molecular Biology
Ana Martinez-Vacas, Johnny Di Pierdomenico, Alejandro Gallego-Ortega, Francisco J. Valiente-Soriano, Manuel Vidal-Sanz, Serge Picaud, Maria Paz Villegas-Perez, Diego Garcia-Ayuso
Summary: The aim of this study was to investigate the neuroprotective effects of taurine administration in dystrophic rats with retinal degeneration. The results showed that taurine treatment increased taurine plasma levels and photoreceptor survival, improved retinal function, reduced inflammation and oxidative stress, and enhanced retinal pigment epithelium function. These findings indicate that taurine has potential neuroprotective effects in retinal degeneration.
Editorial Material
Cell Biology
Johnny Di Pierdomenico, Ana Martinez-Vacas, Serge Picaud, Maria P. Villegas-Perez, Diego Garcia-Ayuso
NEURAL REGENERATION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Maria Jose Gonzalez-Riquelme, Fernando Lucas-Ruiz, Caridad Galindo-Romero, Raquel Boia, Antonio Francisco Ambrosio, Manuel Vidal-Sanz, Ana Raquel Santiago, Marta Agudo-Barriuso
Summary: This study compares retinal organotypic cultures (ROCs) with in vivo models to study retinal ganglion cell (RGC) death and glial activation. The results show that there are significant differences in glial activation between ROCs and in vivo models, with earlier and different morphological activation in ROCs. Additionally, microglial cell density in ROCs is consistently lower than in vivo. ROCs can be used for proof-of-concept studies on neuroprotection, but long-term experiments should be performed in vivo.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Ophthalmology
Johnny Di Pierdomenico, Raquel Gonzalez-Gonzalez, Francisco J. Valiente-Soriano, Caridad Galindo-Romero, Diego Garcia-Ayuso
Summary: This study investigated the knowledge, training, and clinical practice of Spanish optometrists regarding preventing and controlling myopia progression. A web-based questionnaire was distributed and the results showed that the majority of respondents had over 20 years of experience in the optometry field and were very concerned about the increasing frequency of pediatric myopia. The respondents believed that the efficacy of myopia management is related to the age of prescription and suggested a minimum necessary degree of progression for considering myopia management options. The most commonly prescribed method of myopia correction was single-vision spectacles, followed by orthokeratology and soft-defocus contact lenses.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Caridad Galindo-Romero, Celia L. Rodriguez-Zamora, Diego Garcia-Ayuso, Johnny Di Pierdomenico, Francisco J. Valiente-Soriano
Summary: This study investigated the prevalence of computer vision syndrome (CVS)-related symptoms in a presbyopic population using the computer as the main work tool, and examined the relationship between CVS and electronic device use habits and ergonomic factors. The results showed that the median total symptom score (MTSS) in the presbyopic population was 7 +/- 5 symptoms, with dry eyes, tired eyes, and difficulties in refocusing being the most common symptoms. MTSS was higher in women, laptop computer users, and teleworkers compared to office workers, and was also higher in participants who did not take breaks while working, had inadequate lighting in the workspace, and reported neck or back pain.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Zoology
Francisco M. Nadal-Nicolas, Caridad Galindo-Romero, Fernando Lucas-Ruiz, Nicholas Marsh-Amstrong, Wei Li, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Summary: Univocal identification of retinal ganglion cells (RGCs) is necessary for studying their degeneration and neuroprotection. Retrograde tracing of retinorecipient areas is an invasive technique used in the past, but not feasible in higher mammals. This review analyzed nine markers used to identify RGCs in rats, mice, and macaques, and found BRN3A and RBPMS to be the best markers in terms of specificity and labeling proportion.
ZOOLOGICAL RESEARCH
(2023)