Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant

Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2

(2022) Hongjie Xia et al.   Cell Host & Microbe

Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission

(2022) Alba Escalera et al.   Cell Host & Microbe

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

(2022) Bo Meng et al.   NATURE

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

(2022) Peter J. Halfmann et al.   NATURE

Neutralization against Omicron SARS-CoV-2 from previous non-Omicron infection

(2022) Jing Zou et al.   Nature Communications

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

(2021) Bryan A. Johnson et al.   NATURE

Role of mutational reversions and fitness restoration in Zika virus spread to the Americas

(2021) Jianying Liu et al.   Nature Communications

SARS-CoV-2 spike D614G change enhances replication and transmission

(2021) Bin Zhou et al.   NATURE

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

(2021) Rita E. Chen et al.   NATURE MEDICINE

Engineering SARS-CoV-2 using a reverse genetic system

(2021) Xuping Xie et al.   Nature Protocols

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development

(2021) Nicholas Murgolo et al.   PLoS Pathogens

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

(2021) Thomas P. Peacock et al.   Nature Microbiology

Replicative Fitness of a SARS-CoV-2 20I/501Y.V1 Variant from Lineage B.1.1.7 in Human Reconstituted Bronchial Epithelium

(2021) Franck Touret et al.   mBio

Author Correction: Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape

(2021) Zhiqiang Ku et al.   Nature Communications

Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021

(2021) Catherine M. Brown et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

The N501Y spike substitution enhances SARS-CoV-2 infection and transmission

(2021) Yang Liu et al.   NATURE

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

(2021) Akatsuki Saito et al.   NATURE

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

“Submergence” of Western equine encephalitis virus: Evidence of positive selection argues against genetic drift and fitness reductions

(2020) Nicholas A. Bergren et al.   PLoS Pathogens

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

An Infectious cDNA Clone of SARS-CoV-2

(2020) Xuping Xie et al.   Cell Host & Microbe

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

(2020) Shutoku Matsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

(2020) Leonid Yurkovetskiy et al.   CELL

Spike mutation D614G alters SARS-CoV-2 fitness

(2020) Jessica A. Plante et al.   NATURE

Genetic Drift during Systemic Arbovirus Infection of Mosquito Vectors Leads to Decreased Relative Fitness during Host Switching

(2016) Nathan D. Grubaugh et al.   Cell Host & Microbe

A Comparison of Methods to Measure Fitness in Escherichia coli

(2015) Michael J. Wiser et al.   PLoS One