Interferon-γ increases sensitivity to chemotherapy and provides immunotherapy targets in models of metastatic castration-resistant prostate cancer
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Title
Interferon-γ increases sensitivity to chemotherapy and provides immunotherapy targets in models of metastatic castration-resistant prostate cancer
Authors
Keywords
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Journal
Scientific Reports
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-04-22
DOI
10.1038/s41598-022-10724-9
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- (2018) A R Hansen et al. ANNALS OF ONCOLOGY
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