βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug–tubulin interactions and microtubule stability

Title
βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug–tubulin interactions and microtubule stability
Authors
Keywords
Microtubule targeting agents, Peloruside, Laulimalide, Paclitaxel, Tubulin binding sites, Cancer cell resistance
Journal
CANCER LETTERS
Volume 365, Issue 2, Pages 251-260
Publisher
Elsevier BV
Online
2015-06-06
DOI
10.1016/j.canlet.2015.06.001

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