4.4 Review

The state of freeze-for-all in human ARTs

Journal

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
Volume 33, Issue 12, Pages 1543-1550

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10815-016-0799-9

Keywords

Vitrification; Freeze-all; OHSS; PGS; Low responders; Perinatal outcome; Segmentation

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The recent development of vitrification technologies and the good outcomes obtained in assisted reproduction technologies have supported new indications for freezing and segmentation of treatment. Beyond OHSS prevention and avoidance of embryo transfers in the setting of an adverse endocrinological profile or endometrial cavity, we have witnessed a trend to shift fresh embryo transfers to frozen embryo transfers in many programs. We critically review the available evidence and suggest that freeze-all is not for all, but should be individualized.

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