STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)

A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection

(2021) Fiachra Humphries et al.   Science Immunology

Pharmacological activation of STING blocks SARS-CoV-2 infection

(2021) Minghua Li et al.   Science Immunology

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

(2020) Shelbi Christgen et al.   Frontiers in Cellular and Infection Microbiology

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

(2020) Parimal Samir et al.   Frontiers in Cellular and Infection Microbiology

Crosstalk between cGAS–STING signaling and cell death

(2020) Ambika M. V. Murthy et al.   CELL DEATH AND DIFFERENTIATION

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

(2020) Leila Motedayen Aval et al.   Journal of Clinical Medicine

Self-DNA Sensing in Lung Inflammatory Diseases

(2019) Sulayman Benmerzoug et al.   TRENDS IN IMMUNOLOGY

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

(2019) Melanie Fritsch et al.   NATURE

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

(2019) Yang Liu et al.   Nature Communications

Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice

(2019) Mégane Nascimento et al.   Scientific Reports

Design of amidobenzimidazole STING receptor agonists with systemic activity

(2018) Joshi M. Ramanjulu et al.   NATURE

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

(2018) Sulayman Benmerzoug et al.   Nature Communications

A noncanonical function of cGAMP in inflammasome priming and activation

(2017) Karen V. Swanson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signalling strength determines proapoptotic functions of STING

(2017) Muhammet F. Gulen et al.   Nature Communications

Accurate quantification of mouse mitochondrial DNA without co-amplification of nuclear mitochondrial insertion sequences

(2016) Afshan N. Malik et al.   MITOCHONDRION

Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants

(2015) Melissa C. Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA

(2014) Roberto Lande et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

(2014) Seng-Ryong Woo et al.   IMMUNITY

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

STING manifests self DNA-dependent inflammatory disease

(2012) J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

(2010) J. W. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA