Review
Acoustics
Cizar Chway, Sandra Florez, Maria Dolores Munoz, Stefano Guerriero, Juan Luis Alcazar
Summary: Transvaginal ultrasound (TVU) is a valuable tool for preoperative diagnosis of ureteral involvement in women with deep infiltrating endometriosis (DIE).
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Review
Acoustics
S. Guerriero, L. Martinez, I. Gomez, M. A. Pascual, S. Ajossa, M. Pagliuca, J. L. Alcazar
Summary: Transvaginal sonography has low sensitivity but high specificity for detecting parametrial deep endometriosis. Visualization of suspected lesions on TVS significantly increases the post-test probability of parametrial deep endometriosis.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Manoel Orlando Goncalves, Joao Siufi Neto, Marina Paula Andres, Daniela Siufi, Leandro Accardo de Mattos, Mauricio S. Abrao
Summary: DL was able to detect retrocervical, ovarian, and bladder endometriosis with similar sensitivity and specificity as TVUS-BP, whereas for vaginal and rectosigmoid endometriosis, DL had lower sensitivity and specificity than TVUS-BP. The study showed that TVUS-BP is an accurate tool for diagnosing ovarian and deep endometriosis, with higher sensitivity in detecting rectosigmoid endometriosis compared to DL.
HUMAN REPRODUCTION
(2021)
Review
Acoustics
J. L. Alcazar, P. M. Eguez, P. Forcada, E. Ternero, C. Martinez, M. A. Pascual, S. Guerriero
Summary: This systematic review and meta-analysis evaluated the diagnostic accuracy of the sliding sign on transvaginal ultrasound in detecting pouch of Douglas obliteration and bowel involvement in patients with suspected endometriosis, using laparoscopy as the reference standard. The results showed that the sliding sign had good diagnostic performance for predicting pouch of Douglas obliteration and bowel involvement.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Acoustics
Cristina Ros, Cristian de Guirior, Mariona Rius, Silvia Escura, Maria Angeles Martinez-Zamora, Meritxell Gracia, Lluis Peri, Agustin Franco, Francisco Carmona
Summary: Transvaginal ultrasound is accurate in identifying infiltration of bladder endometriosis nodules and predicting cystoscopic findings. Nodules that partially involve the muscular layer typically have normal cystoscopic results, eliminating the need for the procedure. Bladder endometriosis nodules are commonly associated with other forms of endometriosis and typically do not affect the ureteral meatus.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Review
Acoustics
E. Pascoal, J. M. Wessels, M. K. Aas-Eng, M. S. Abrao, G. Condous, D. Jurkovic, M. Espada, C. Exacoustos, S. Ferrero, S. Guerriero, G. Hudelist, M. Malzoni, S. Reid, S. Tang, C. Tomassetti, S. S. Singh, T. van den Bosch, M. Leonardi
Summary: Endometriosis is a chronic systemic disease that can greatly impact patients' quality of life. Diagnosing endometriosis is challenging, and various methods have their strengths and limitations. Currently, there is no single gold-standard diagnostic method, and different circumstances may require different diagnostic approaches.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Soo Youn Song, Ye Won Jung, WonKyo Shin, Mia Park, Geon Woo Lee, Soohwa Jeong, Sukjeong An, Kyoungmin Kim, Young Bok Ko, Ki Hwan Lee, Byung Hun Kang, Mina Lee, Heon Jong Yoo
Summary: Endometriosis, a common gynecologic disease, often leads to various pain symptoms such as dysmenorrhea, dyspareunia, and chronic pelvic pain. Inflammatory responses, nervous system sensitization, and altered distribution of nerve fibers may contribute to chronic pain in these patients. Understanding these mechanisms is crucial in guiding treatment decisions for endometriosis-related pain symptoms.
Article
Acoustics
Francesco G. Martire, Errico Zupi, Lucia Lazzeri, Giulia Morosetti, Francesca Conway, Gabriele Centini, Eugenio Solima, Adalgisa Pietropolli, Emilio Piccione, Caterina Exacoustos
Summary: This study evaluated TVUS findings in patients who underwent rectosigmoid resection for DIE, finding a high percentage of adhesions and recurrence of posterior DIE. Adenomyosis was observed in 80% of women, indicating its potential link to postoperative symptoms. This suggests that postoperative TVUS can be useful for detecting persistent disease or pelvic adhesions in symptomatic patients.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Article
Acoustics
C. Ros, M. Rius, M. S. Abrao, C. DeGuirior, M. A. Martinez-Zamora, M. Gracia, F. Carmona
Summary: This study aimed to analyze the impact of bowel preparation on the detection of bowel involvement and rectosigmoid nodules of deep infiltrating endometriosis (DIE) during transvaginal ultrasound (TVS) examination. Results showed that patients tolerated bowel preparation well, and it improved the detection of nodules, providing a more detailed description for patients with suspected endometriosis.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Review
Medicine, General & Internal
Stefano Guerriero, Silvia Ajossa, Mariachiara Pagliuca, Antonietta Borzacchelli, Fabio Deiala, Serena Springer, Monica Pilloni, Valeria Taccori, Maria Angela Pascual, Betlem Graupera, Luca Saba, Juan Luis Alcazar
Summary: With the development of standardized diagnostic protocols and improved technology, the use of imaging techniques for the diagnosis of pelvic endometriosis has become a reality. Transvaginal ultrasound and magnetic resonance imaging are now the two accurate imaging techniques that can identify the majority of endometriosis phenotypes.
Review
Medicine, General & Internal
Alexandra Bausic, Ciprian Coroleuca, Catalin Coroleuca, Diana Comandasu, Roxana Matasariu, Andrei Manu, Francesca Frincu, Claudia Mehedintu, Elvira Bratila
Summary: Endometriosis is a common gynecological condition that can cause various symptoms in women of reproductive age. Accurate diagnosis is essential for effective treatment, and different diagnostic methods should be chosen based on the type of endometriosis.
Article
Medicine, General & Internal
Bogdan Doroftei, Radu Maftei, Ovidiu-Dumitru Ilie, Gabriela Simionescu, Emil Anton, Theodora Armeanu, Ana-Maria Dabuleanu, Elena Mihalceanu, Constantin Condac, Ciprian Ilea
Summary: Endometriosis is a benign condition characterized by systemic inflammation that affects fertile women, and ultrasound has become the method of choice for effective diagnosis and preoperative planning in recent years. Accurate characterization and mapping of endometriotic lesions are crucial for optimal treatment, whether surgical or non-surgical, based on severity.
Article
Radiology, Nuclear Medicine & Medical Imaging
Basma Al-Arnawoot, Silvia Chang, Shauna Duigenan, Ania Z. Kielar, Mathew Leonardi
Summary: The Canadian Association of Radiologists (CAR) Endometriosis Working Group has provided a practice statement on the use of advanced pelvic ultrasound for the diagnosis and mapping of pelvic endometriosis. This statement aims to guide radiologists in implementing these techniques and starting an ultrasound endometriosis evaluation program.
CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES
(2023)
Article
Oncology
H. Verschuere, W. Froyman, T. Van den Bosch, M. Van Hoefs, J. Kaijser, D. Van Schoubroeck, A. S. Van Rompuy, I Vergote, D. Timmerman
Summary: This study retrospectively analyzed women who underwent transvaginal ultrasound-guided tru-cut biopsies at the Department of Obstetrics and Gynecology of the University Hospitals Leuven from June 2014 to October 2018. The results showed that the procedure is safe and accurate for diagnosing pelvic masses, with at least 2 core biopsies recommended for an adequate and accurate diagnosis.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Obstetrics & Gynecology
Alexis Roditis, Marie Florin, Pascal Rousset, Cyril Touboul, Sofiane Bendifallah, Marc Bazot, Isabelle Thomassin-Naggara
Summary: This study aimed to assess the diagnostic ability of physical examination (PE), transvaginal ultrasonography (TVUS), and magnetic resonance imaging (MRI) alone and combined for deep infiltrating endometriosis (DIE). The results showed that MRI was more sensitive than PE, TVUS, or any combination for detecting DIE. Furthermore, the combination of PE, TVUS, and MRI was more accurate than each technique separately for diagnosing DIE.
FERTILITY AND STERILITY
(2023)
Review
Acoustics
Juan Luis Alcazar, Patricia Carazo, Leyre Pegenaute, Elena Gurrea, Irene Campos, Manuela Neri, Maria Angela Pascual, Stefano Guerriero
ULTRASCHALL IN DER MEDIZIN
(2023)
Review
Acoustics
I. Garde, C. Paredes, L. Ventura, M. A. Pascual, S. Ajossa, S. Guerriero, J. Vara, M. Linares, J. L. Alcazar
Summary: This is a study evaluating the diagnostic accuracy of different ultrasound signs for diagnosing adnexal torsion using surgery as the reference standard. The presence of ovarian edema, adnexal mass, ovarian Doppler flow findings, the whirlpool sign, and pelvic fluid were analyzed as ultrasound signs. The results showed that ovarian edema, the whirlpool sign, and decreased or absent ovarian Doppler flow have good specificity but moderate sensitivity for detecting adnexal torsion, while the presence of an adnexal mass or pelvic fluid had poor diagnostic accuracy.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Review
Obstetrics & Gynecology
Juan Luis Alcazar, Julio Vara, Claudia Usandizaga, Silvia Ajossa, Maria A. Pascual, Stefano Guerriero
Summary: This study compared the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for adenomyosis. The results showed that both TVS and MRI had similar performances in diagnosing adenomyosis. Rating: 8/10.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Letter
Acoustics
R. Heremans, T. van den Bosch, P. Sladkevicius, M. A. Pascual, J. L. Alcazar, D. Timmerman, L. Valentin
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Medicine, General & Internal
Marcelo Pedrassani, Stefano Guerriero, Maria Angela Pascual, Silvia Ajossa, Betlem Graupera, Mariachiara Pagliuca, Sergio Podgaec, Esdras Camargos, Ygor Vieira de Oliveira, Juan Luis Alcazar
Summary: This study aimed to describe the appearance of superficial endometriosis lesions at ultrasound examination, and found that these lesions may exhibit different ultrasound features. Transvaginal ultrasound may be useful for diagnosing superficial endometriosis.
Review
Medicine, General & Internal
Aina Delgado-Morell, Mar Nieto-Tous, Cristina Andrada-Ripolles, Maria Angela Pascual, Silvia Ajossa, Stefano Guerriero, Juan Luis Alcazar
Summary: Hydrosalpinx is an important factor in reproduction and ultrasound is an effective non-invasive technique for diagnosing it. This study aimed to summarize and report the current evidence on the accuracy of transvaginal sonography (TVS) in diagnosing hydrosalpinx. Six studies were analyzed, involving 3974 women and 4144 adnexal masses, with 118 cases of hydrosalpinx. The overall sensitivity of TVS in diagnosing hydrosalpinx was 84%, with a specificity of 99%, positive likelihood ratio of 80.7, negative likelihood ratio of 0.16, and DOR of 496.
Article
Medicine, General & Internal
Julio Vara, Mariachiara Pagliuca, Serena Springer, Juan Gonzalez de Canales, Isabel Brotons, Javiera Yakcich, Silvia Ajossa, Maria Angela Pascual, Stefano Guerriero, Juan Luis Alcazar
Summary: The objective of this study was to assess the agreement and diagnostic performance of O-RADS using the IOTA lexicon or ADNEX model. The results showed moderate agreement between the two methods, with a 46% agreement rate. The sensitivity and specificity for O-RADS using the IOTA lexicon were 92.2% and 86.1%, and for using the ADNEX model were 85.9% and 87.4%, respectively. In conclusion, the diagnostic performance of O-RADS classification using the IOTA lexicon and ADNEX model is similar but the group assignment varies significantly.
Review
Medicine, General & Internal
Juan Luis Alcazar, Isabel Carriles, Maria Belen Cajas, Susana Costa, Sofia Fabra, Maria Cabrero, Elena Castro, Aida Tomaizeh, Maria Victoria Laza, Alba Monroy, Irene Martinez, Maria Isabel Aguilar, Elena Hernani, Cristina Castellet, Agustin Oliva, Maria angela Pascual, Stefano Guerriero
Summary: This meta-analysis examined the diagnostic performance of various ultrasound techniques for the septate uterus. The results showed that three-dimensional transvaginal ultrasound had the highest diagnostic accuracy.
Article
Medicine, General & Internal
Jean L. L. Browne, Maria Angela Pascual, Jorge Perez, Sulimar Salazar, Beatriz Valero, Ignacio Rodriguez, Dario Cassina, Juan Luis Alcazar, Stefano Guerriero, Betlem Graupera
Summary: This study compares the BI-RADS classification with pathology results and the results of processing images through the AI algorithm KOIOS DS(TM). The findings show that the KOIOS algorithm has a higher ratio of positive biopsies in the BI-RADS 4, 5, and 6 categories, and can help avoid unnecessary biopsies in the BI-RADS 3 category.
Review
Acoustics
Cizar Chway, Sandra Florez, Maria Dolores Munoz, Stefano Guerriero, Juan Luis Alcazar
Summary: Transvaginal ultrasound (TVU) is a valuable tool for preoperative diagnosis of ureteral involvement in women with deep infiltrating endometriosis (DIE).
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Medicine, General & Internal
Noemie Sachs-Guedj, Buenaventura Coroleu, Maria Angela Pascual, Ignacio Rodriguez, Nikolaos Polyzos
Summary: The presence of adenomyosis has a significant negative impact on the clinical outcomes of patients undergoing frozen embryo transfer (FET), leading to higher miscarriage rates, lower clinical pregnancy rates, and lower live birth rates. The use of GnRH agonist pre-treatment does not appear to improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Aurora Santin, Beatrice Spedicati, Anna Morgan, Stefania Lenarduzzi, Paola Tesolin, Giuseppe Giovanni Nardone, Daniela Mazza, Giovanni Di Lorenzo, Federico Romano, Francesca Buonomo, Alessandro Mangogna, Maria Pina Concas, Gabriella Zito, Giuseppe Ricci, Giorgia Girotto
Summary: This study used whole-exome sequencing to investigate genetic mechanisms underlying endometriosis. The results identified several rare and damaging variants in EM-associated genes, as well as novel candidate genes. The findings provide new insights into EM genetics and contribute to the development of personalized care for EM patients.
Article
Health Care Sciences & Services
Ashleigh Ledger, Jolien Ceusters, Lil Valentin, Antonia Testa, Caroline Van Holsbeke, Dorella Franchi, Tom Bourne, Wouter Froyman, Dirk Timmerman, Ben Van Calster
Summary: Assessing the malignancy risk of ovarian tumors is crucial for selecting appropriate management. In this study, six algorithms were compared to estimate the probabilities of different types of ovarian tumors. The models developed showed good performance, but individual probability estimates varied substantially.
BMC MEDICAL RESEARCH METHODOLOGY
(2023)