A sensitive and selective mutation detection strategy based on non-canonical DNA structure preference of endonuclease IV

Endonuclease IV-Regulated DNAzyme Motor for Universal Single-nucleotide Variation Discrimination

(2021) Zhen Zhang et al.   ANALYTICAL CHEMISTRY

Sensitive DNA Mutation Detection at Physiological Temperature with Endonuclease IV by Inhibiting Its Side Activity

(2021) Zhen Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

A cost-effective detection of low-abundance mutation with DNA three-way junction structure and lambda exonuclease

(2020) Zishan Feng et al.   CHINESE CHEMICAL LETTERS

Determination of low-abundance single-base point mutations based on endonuclease IV and branch migration system

(2020) Xiaofeng Tang et al.   ANALYTICA CHIMICA ACTA

Targeted Detection of Single-Nucleotide Variations: Progress and Promise

(2019) Alireza Abi et al.   ACS Sensors

Translating genomic medicine to the clinic: challenges and opportunities

(2019) Huan Zhang et al.   Genome Medicine

Liquid biopsy and minimal residual disease — latest advances and implications for cure

(2019) Klaus Pantel et al.   Nature Reviews Clinical Oncology

Noncanonical substrate preference of lambda exonuclease for 5′-nonphosphate-ended dsDNA and a mismatch-induced acceleration effect on the enzymatic reaction

(2018) Tongbo Wu et al.   NUCLEIC ACIDS RESEARCH

Extending Circulating Tumor DNA Analysis to Ultralow Abundance Mutations: Techniques and Challenges

(2018) Andrew E. Rodda et al.   ACS Sensors

Endonuclease IV recognizes single base mismatch on the eighth base 3′ to the abasic site in DNA strands for ultra-selective and sensitive mutant-type DNA detection

(2018) Jiaju Xu et al.   RSC Advances

Emergence of novel and dominant acquired EGFR solvent-front mutations at Gly796 (G796S/R) together with C797S/R and L792F/H mutations in one EGFR (L858R/T790M) NSCLC patient who progressed on osimertinib

(2017) Sai-Hong Ignatius Ou et al.   LUNG CANCER

Functional precision cancer medicine—moving beyond pure genomics

(2017) Anthony Letai   NATURE MEDICINE

DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA

(2017) Tongbo Wu et al.   NUCLEIC ACIDS RESEARCH

Direct detection of early-stage cancers using circulating tumor DNA

(2017) Jillian Phallen et al.   Science Translational Medicine

Discrimination Cascade Enabled Selective Detection of Single-Nucleotide Mutation

(2017) Lidan Li et al.   ACS Sensors

Detection ofK-rasgene mutation by liquid biopsy in patients with pancreatic cancer

(2015) Hideaki Kinugasa et al.   CANCER

Single-base mismatch discrimination by T7 exonuclease with target cyclic amplification detection

(2015) Zhen-Kun Wu et al.   CHEMICAL COMMUNICATIONS

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

(2015) Kenneth S Thress et al.   NATURE MEDICINE

Endonuclease IV discriminates mismatches next to the apurinic/apyrimidinic site in DNA strands: constructing DNA sensing platforms with extremely high selectivity

(2013) Xianjin Xiao et al.   CHEMICAL COMMUNICATIONS

Combination of a modified block PCR and endonuclease IV-based signal amplification system for ultra-sensitive detection of low-abundance point mutations

(2013) Xianjin Xiao et al.   METHODS

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinicopathological relevance of BRAF mutations in human cancer

(2013) Sahar Pakneshan et al.   PATHOLOGY

Highly sensitive and selective colorimetric genotyping of single-nucleotide polymorphisms based on enzyme-amplified ligation on magnetic beads

(2012) Xiaojun Chen et al.   BIOSENSORS & BIOELECTRONICS

The EGFR T790M Mutation in Acquired Resistance to an Irreversible Second-Generation EGFR Inhibitor

(2012) Y. Kim et al.   MOLECULAR CANCER THERAPEUTICS

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

(2012) R. J. Leary et al.   Science Translational Medicine

A universal mismatch-directed signal amplification platform for ultra-selective and sensitive DNA detection under mild isothermal conditions

(2012) Xianjin Xiao et al.   Chemical Science

Fluorescent hybridization probes for nucleic acid detection

(2011) Jia Guo et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ultra-selective and sensitive DNA detection by a universal apurinic/apyrimidinic probe-based endonuclease IV signal amplification system

(2011) Xianjin Xiao et al.   CHEMICAL COMMUNICATIONS

BRAFV600E detection in melanoma is highly improved by COLD-PCR

(2011) Pamela Pinzani et al.   CLINICA CHIMICA ACTA

The endonuclease IV family of apurinic/apyrimidinic endonucleases

(2010) James M. Daley et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Fluorescence Detection of Single-Nucleotide Polymorphisms with a Single, Self-Complementary, Triple-Stem DNA Probe

(2009) Yi Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION