Hepatic myeloid-derived suppressor cells in cancer

Tadalafil Augments Tumor Specific Immunity in Patients with Head and Neck Squamous Cell Carcinoma

(2015) J. A. Califano et al.   CLINICAL CANCER RESEARCH

Tumor-induced CD11b+ Gr-1+ myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner

(2015) Tamar Kapanadze et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism

(2015) Daisaku Yamada et al.   HEPATOLOGY

CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice

(2015) Yunching Chen et al.   HEPATOLOGY

Contact-Dependent Depletion of Hydrogen Peroxide by Catalase Is a Novel Mechanism of Myeloid-Derived Suppressor Cell Induction Operating in Human Hepatic Stellate Cells

(2015) Yazid J. Resheq et al.   JOURNAL OF IMMUNOLOGY

Systemic Agonistic Anti-CD40 Treatment of Tumor-Bearing Mice Modulates Hepatic Myeloid-Suppressive Cells and Causes Immune-Mediated Liver Damage

(2015) José Medina-Echeverz et al.   Cancer Immunology Research

IL-17A Produced by    T Cells Promotes Tumor Growth in Hepatocellular Carcinoma

(2014) S. Ma et al.   CANCER RESEARCH

Agonistic anti-CD137 antibody treatment leads to antitumor response in mice with liver cancer

(2014) Vanessa Gauttier et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Alternative Macrophage Activation by Galectin-3

(2014) A. C. MacKinnon et al.   JOURNAL OF IMMUNOLOGY

Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Liver metastases induce reversible hepatic B cell dysfunction mediated by Gr-1+CD11b+ myeloid cells

(2014) Mitchell Thorn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice

(2014) Hong Qin et al.   NATURE MEDICINE

Tumor Induced Hepatic Myeloid Derived Suppressor Cells Can Cause Moderate Liver Damage

(2014) Tobias Eggert et al.   PLoS One

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer

(2013) K. Schmidt et al.   BLOOD

Myeloid-Derived Suppressor Cells as a Vehicle for Tumor-Specific Oncolytic Viral Therapy

(2013) S. Eisenstein et al.   CANCER RESEARCH

Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality

(2013) S. Kalathil et al.   CANCER RESEARCH

Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial

(2013) Ann-Lii Cheng et al.   JOURNAL OF CLINICAL ONCOLOGY

Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion

(2013) Bastian Höchst et al.   JOURNAL OF HEPATOLOGY

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

(2013) Tamar Kapanadze et al.   JOURNAL OF HEPATOLOGY

Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3

(2013) B. Linju Yen et al.   Stem Cell Reports

Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis

(2013) Su Yin Lim et al.   OncoImmunology

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies

(2012) Austin Duffy et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Suppression, subversion and escape: the role of regulatory T cells in cancer progression

(2012) K. Oleinika et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Molecular Pathways: Tumor-Infiltrating Myeloid Cells and Reactive Oxygen Species in Regulation of Tumor Microenvironment

(2012) T. Lu et al.   CLINICAL CANCER RESEARCH

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer

(2012) Carlo Schneider et al.   GUT

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis*

(2012) Lei Zhao et al.   HEPATOLOGY

Anti-Gr-1 antibody depletion fails to eliminate hepatic myeloid-derived suppressor cells in tumor-bearing mice

(2012) Chi Ma et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

(2012) Avijit Majumdar et al.   Nature Reviews Gastroenterology & Hepatology

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

(2012) Zvi G. Fridlender et al.   PLoS One

Functional Role of Monocytes and Macrophages for the Inflammatory Response in Acute Liver Injury

(2012) Henning W. Zimmermann et al.   Frontiers in Physiology

In vivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory site

(2011) Jessica M. Haverkamp et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid derived suppressor cells in human diseases

(2011) Tim F. Greten et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

(2011) Je-In Youn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model

(2011) Mengde Cao et al.   LABORATORY INVESTIGATION

Interleukin-6 Induces Gr-1+CD11b+ Myeloid Cells to Suppress CD8+ T Cell-Mediated Liver Injury in Mice

(2011) Liang Cheng et al.   PLoS One

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice

(2010) M. Gonzalez-Aparicio et al.   GUT

CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice

(2010) Yue Si et al.   JOURNAL OF CLINICAL INVESTIGATION

Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model

(2010) T. Kitamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies

(2009) J. Ozao-Choy et al.   CANCER RESEARCH

The Liver Is a Site for Tumor-Induced Myeloid-Derived Suppressor Cell Accumulation and Immunosuppression

(2009) Dan Ilkovitch et al.   CANCER RESEARCH

Immature myeloid cells induced by a high-fat diet contribute to liver inflammation

(2009) Zhong-bin Deng et al.   HEPATOLOGY

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor

(2009) Bastian Hoechst et al.   HEPATOLOGY

CCR2 promotes hepatic fibrosis in mice

(2009) Ekihiro Seki et al.   HEPATOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor

(2009) Michael K. Connolly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

(2008) Y. Sawanobori et al.   BLOOD

A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells

(2008) Bastian Hoechst et al.   GASTROENTEROLOGY