An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo

SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

(2022) Wanwisa Dejnirattisai et al.   CELL

Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2

(2022) Pengcheng Han et al.   CELL

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

(2022) Zhen Cui et al.   CELL

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

(2022) Delphine Planas et al.   NATURE

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

(2022) Peter J. Halfmann et al.   NATURE

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

(2022) Yunlong Cao et al.   NATURE

Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants

(2022) Lianghui Zhang et al.   Nature Chemical Biology

An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

(2022) Laura A. VanBlargan et al.   NATURE MEDICINE

SARS-CoV-2 Omicron Variant Neutralization in Serum from Vaccinated and Convalescent Persons

(2022) Annika Rössler et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex

(2022) Dhiraj Mannar et al.   SCIENCE

The Tissue Distribution of SARS-CoV-2 in Transgenic Mice With Inducible Ubiquitous Expression of hACE2

(2022) Alexander A. Dolskiy et al.   Frontiers in Molecular Biosciences

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

(2021) Tyler N. Starr et al.   SCIENCE

No higher infectivity but immune escape of SARS-CoV-2 501Y.V2 variants

(2021) Qianqian Li et al.   CELL

Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

(2021) Gabriele Cerutti et al.   Cell Host & Microbe

Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape

(2021) Kevin R. McCarthy et al.   SCIENCE

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

(2021) Kui K. Chan et al.   Science Advances

Broad sarbecovirus neutralization by a human monoclonal antibody

(2021) M. Alejandra Tortorici et al.   NATURE

Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors

(2021) Chee-Wah Tan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

(2021) Kathryn M. Hastie et al.   SCIENCE

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

(2021) Allison J. Greaney et al.   Science Translational Medicine

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

(2021) Yusuke Higuchi et al.   Nature Communications

Highly susceptible SARS-CoV-2 model in CAG promoter-driven hACE2 transgenic mice

(2021) Masamitsu N. Asaka et al.   JCI Insight

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

(2021) Markus Hoffmann et al.   CELL

The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus

(2021) Wenjuan Dong et al.   JOURNAL OF VIROLOGY

Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum

(2021) Wanwisa Dejnirattisai et al.   LANCET

Effectiveness of BNT162b2 Vaccine against Omicron Variant in South Africa

(2021) Shirley Collie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralization of the SARS-CoV-2 Mu Variant by Convalescent and Vaccine Serum

(2021) Keiya Uriu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

(2020) Tyler N. Starr et al.   CELL

Super-rapid quantitation of the production of HIV-1 harboring a luminescent peptide tag

(2020) Seiya Ozono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

(2020) Alina Baum et al.   SCIENCE

Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2

(2020) Kui K. Chan et al.   SCIENCE

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

(2020) Anum Glasgow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Simplified Quantitative Real-Time PCR Assay for Monitoring SARS-CoV-2 Growth in Cell Culture

(2020) Christian Shema Mugisha et al.   mSphere

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

(2019) Atsushi Hoshino et al.   NATURE

Mapping mutational effects along the evolutionary landscape of HIV envelope

(2018) Hugh K Haddox et al.   eLife

Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

(2018) Juhye M. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION